{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T22:03:20Z","timestamp":1783721000928,"version":"3.55.0"},"reference-count":15,"publisher":"Korean Society of Clinical Oncology","issue":"2","content-domain":{"domain":["kjco.org"],"crossmark-restriction":true},"short-container-title":["Korean J Clin Oncol"],"abstract":"<jats:p>Extrauterine endometrial stromal sarcoma arising from malignant transformation of the vagina is an extremely rare condition. The diagnosis is often difficult as the symptomatology and pathological features overlap with that of pelvic endometriosis. A 38 years old female presented with complaints of dyspareunia, dysmenorrhea, and painful defecation along with blood-stained vaginal discharge for a year. Examination revealed the presence of multiple brownish irregular nodules in posterior vaginal fornix and fixed tender nodules which on biopsy revealed florid vaginal endometriosis. She improved symptomatically on medical therapy. After 18 months of diagnosis, she presented again with a necrotic growth in posterior fornix, which on repeat biopsy revealed a low-grade endometrial stromal sarcoma. Laparotomy revealed a 7\u00d75 cm mass in the pouch of Douglas, infiltrating the posterior vaginal wall and rectum. A complete cytoreductive surgery with retrograde hysterectomy, excision of posterior vaginal wall and rectosigmoid resection was done. The patient is disease-free at a follow-up of 65 months.<\/jats:p>","DOI":"10.14216\/kjco.23013","type":"journal-article","created":{"date-parts":[[2024,1,5]],"date-time":"2024-01-05T01:32:53Z","timestamp":1704418373000},"page":"73-79","update-policy":"https:\/\/doi.org\/10.14216\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Low-grade extrauterine endometrial stromal sarcoma arising from vaginal endometriosis: a case report and literature review"],"prefix":"10.14216","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8644-7684","authenticated-orcid":true,"given":"Seema","family":"Singhal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6913-6876","authenticated-orcid":true,"given":"Aarthi S","family":"Jayraj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8265-9674","authenticated-orcid":true,"given":"Ekta","family":"Dhamija","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6308-5481","authenticated-orcid":true,"given":"Sachin","family":"Khurana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5309","published-online":{"date-parts":[[2023,12,31]]},"reference":[{"key":"ref1","first-page":"1635","volume-title":"Endometrioid stromal sarcoma: a clinicopathologic study of 63 cases","author":"Masand","year":"2013"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1159\/000336522"},{"key":"ref3","first-page":"34s","volume-title":"Endometrial stromal sarcoma arising from vaginal endometriosis","author":"Berkowitz","year":"1978"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/76.4.371"},{"key":"ref5","first-page":"588","volume-title":"Stromal sarcoma arising on endometriosis: a clinicopathological and immunohistochemical study of 4 cases","author":"Kondi-Paphitis","year":"1998"},{"key":"ref6","first-page":"714","volume-title":"Endometrial stromal sarcoma of the vagina","author":"Chang","year":"2000"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.anndiagpath.2004.07.007"},{"key":"ref8","first-page":"2997","volume-title":"Endometrial stromal sarcoma arising in vagina","author":"Liu","year":"2013"},{"key":"ref9","first-page":"433","volume-title":"Low-grade endometrial stromal sarcoma primarily arising in the vagina: a case report","author":"Rivard","year":"2015"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111\/jog.12746"},{"key":"ref11","first-page":"717","volume-title":"Primary vaginal endometrial stromal sarcoma associated with endometriosis: a case report with a review of the literature","author":"Sanverdi","year":"2016"},{"key":"ref12","first-page":"rjx238","volume-title":"Primary low-grade endometrial stromal sarcoma arising in the vagina: report of an unusual case and literature review","author":"Abu Jamea","year":"2017"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1038\/s41379-020-0535-y"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1097\/pgp.0000000000000626"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1186\/s12957-021-02474-1"}],"container-title":["Korean Journal of Clinical Oncology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/kjco.org\/upload\/pdf\/kjco-19-2-73.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,15]],"date-time":"2024-01-15T01:13:24Z","timestamp":1705281204000},"score":1,"resource":{"primary":{"URL":"http:\/\/kjco.org\/journal\/view.php?doi=10.14216\/kjco.23013"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,31]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,12,1]]}},"URL":"https:\/\/doi.org\/10.14216\/kjco.23013","relation":{},"ISSN":["1738-8082","2288-4084"],"issn-type":[{"value":"1738-8082","type":"print"},{"value":"2288-4084","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,31]]},"assertion":[{"value":"2023-07-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-31","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}