{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T08:10:42Z","timestamp":1778141442621,"version":"3.51.4"},"reference-count":14,"publisher":"Korean Society of Clinical Oncology","issue":"1","funder":[{"DOI":"10.13039\/501100002543","name":"Pusan National University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002543","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["kjco.org"],"crossmark-restriction":true},"short-container-title":["Korean J Clin Oncol"],"abstract":"<jats:p>Immunoglobulin G4 (IgG4)-related disease is a fibroinflammatory condition that can involve multiple organs. Isolated involvement of the gallbladder is exceptionally uncommon and often radiologically indistinguishable from gallbladder carcinoma, resulting in diagnostic uncertainty before surgery. A 77-year-old man presented with right upper abdominal discomfort lasting 1 month. Cross-sectional imaging revealed irregular gallbladder wall thickening with contrast enhancement, raising suspicion for resectable gallbladder cancer. The patient underwent a radical cholecystectomy with partial hepatectomy. Histopathological analysis demonstrated dense lymphoplasmacytic infiltration, storiform fibrosis, and marked infiltration of IgG4-positive plasma cells exceeding established diagnostic thresholds, consistent with IgG4-related cholecystitis. The postoperative course was uneventful, and no additional treatment was required. IgG4-related cholecystitis should be considered in the differential diagnosis of gallbladder malignancy, particularly in atypical or indeterminate cases. However, when imaging findings strongly suggest carcinoma, radical surgical resection remains an appropriate oncologic approach.<\/jats:p>","DOI":"10.14216\/kjco.26385","type":"journal-article","created":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:57:27Z","timestamp":1777510647000},"page":"28-32","update-policy":"https:\/\/doi.org\/10.14216\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Isolated IgG4-related cholecystitis mimicking locally advanced gallbladder cancer: a case report"],"prefix":"10.14216","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7764-9516","authenticated-orcid":true,"given":"Byeong Gwan","family":"Noh","sequence":"first","affiliation":[{"name":"Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4132-7662","authenticated-orcid":true,"given":"Hyung Il","family":"Seo","sequence":"additional","affiliation":[{"name":"Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4165-3054","authenticated-orcid":true,"given":"Young Mok","family":"Park","sequence":"additional","affiliation":[{"name":"Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-7303-0835","authenticated-orcid":true,"given":"Myeong Hun","family":"Oh","sequence":"additional","affiliation":[{"name":"Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5309","published-online":{"date-parts":[[2026,4,30]]},"reference":[{"key":"ref1","first-page":"1181","volume-title":"Consensus statement on the pathology of IgG4-related disease","author":"Deshpande","year":"2012"},{"key":"ref2","first-page":"21","volume-title":"Comprehensive diagnostic criteria for IgG4-related disease (IgG4-RD), 2011","author":"Umehara","year":"2012"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2025.102108"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1186\/s12876-022-02179-z"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.hpb.2024.07.411"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinimag.2013.01.015"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-014-2568-3"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1186\/s40792-015-0123-4"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1002\/jgh3.12154"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s12328-020-01168-7"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1055\/a-2177-3793"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.m1067"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1002\/art.41120"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1080\/14397595.2020.1859710"}],"container-title":["Korean Journal of Clinical Oncology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.kjco.org\/upload\/pdf\/kjco-26385.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T07:14:52Z","timestamp":1778138092000},"score":1,"resource":{"primary":{"URL":"http:\/\/kjco.org\/journal\/view.php?doi=10.14216\/kjco.26385"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,30]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,4,1]]}},"URL":"https:\/\/doi.org\/10.14216\/kjco.26385","relation":{},"ISSN":["1738-8082","2288-4084"],"issn-type":[{"value":"1738-8082","type":"print"},{"value":"2288-4084","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,30]]},"assertion":[{"value":"2026-01-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-03","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-30","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}