{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T12:08:35Z","timestamp":1790683715659,"version":"4.1.0"},"reference-count":25,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2008,5,1]],"date-time":"2008-05-01T00:00:00Z","timestamp":1209600000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of the American Dental Association"],"published-print":{"date-parts":[[2008,5]]},"DOI":"10.14219\/jada.archive.2008.0222","type":"journal-article","created":{"date-parts":[[2014,1,9]],"date-time":"2014-01-09T00:56:14Z","timestamp":1389228974000},"page":"606-611","source":"Crossref","is-referenced-by-count":71,"title":["Antimicrobial Effectiveness of an Herbal Mouthrinse Compared With an Essential Oil and a Chlorhexidine Mouthrinse"],"prefix":"10.1016","volume":"139","author":[{"given":"Anne D.","family":"Haffajee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tina","family":"Yaskell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sigmund S.","family":"Socransky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"suppl 6","key":"10.14219\/jada.archive.2008.0222_bib1","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1111\/j.1600-051X.2005.00821.x","article-title":"Generation of inflammatory stimuli: how bacteria set up inflammatory responses in the gingiva","volume":"32","author":"Madianos","year":"2005","journal-title":"J Clin Periodontol"},{"issue":"11 suppl","key":"10.14219\/jada.archive.2008.0222_bib2","first-page":"5S","article-title":"Antimicrobial mouthrinses and the management of periodontal diseases: introduction to the supplement","volume":"137","author":"Lamster","year":"2006","journal-title":"JADA"},{"issue":"6","key":"10.14219\/jada.archive.2008.0222_bib3","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1056\/NEJM199002083220606","article-title":"Periodontal disease","volume":"322","author":"Williams","year":"1990","journal-title":"N Engl J Med"},{"issue":"3","key":"10.14219\/jada.archive.2008.0222_bib4","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1111\/j.1600-051X.1998.tb02433.x","article-title":"Gingival inflammation and subgingival calculus as determinants of disease progression in early-onset periodontitis","volume":"25","author":"Albandar","year":"1998","journal-title":"J Clin Periodontol"},{"issue":"6","key":"10.14219\/jada.archive.2008.0222_bib5","first-page":"699","article-title":"The role of therapeutic antimicrobial mouthrinses in clinical practice: control of supragingival plaque and gingivitis","volume":"134","author":"Barnett","year":"2003","journal-title":"JADA"},{"issue":"4","key":"10.14219\/jada.archive.2008.0222_bib6","first-page":"496","article-title":"Adjunctive benefit of an essential oil-containing mouthrinse in reducing plaque and gingivitis in patients who brush and floss regularly: a six-month study","volume":"135","author":"Sharma","year":"2004","journal-title":"JADA"},{"issue":"6","key":"10.14219\/jada.archive.2008.0222_bib7","first-page":"351","article-title":"Comparative effectiveness of an essential oil mouthrinse and dental floss in controlling interproximal gingivitis and plaque","volume":"15","author":"Sharma","year":"2002","journal-title":"Am J Dent"},{"issue":"4","key":"10.14219\/jada.archive.2008.0222_bib8","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1111\/j.1600-051x.2005.00674.x","article-title":"In vivo antimicrobial effectiveness of an essential oil-containing mouth rinse 12 h after a single use and 14 days' use","volume":"32","author":"Fine","year":"2005","journal-title":"J Clin Periodontol"},{"issue":"suppl 5","key":"10.14219\/jada.archive.2008.0222_bib9","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1034\/j.1600-051X.30.s5.5.x","article-title":"Evidence-based control of plaque and gingivitis","volume":"30","author":"Santos","year":"2003","journal-title":"J Clin Periodontol"},{"issue":"8","key":"10.14219\/jada.archive.2008.0222_bib10","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1111\/j.1600-051X.1990.tb01108.x","article-title":"Comparative effects of 2 chemotherapeutic mouthrinses on the development of supragingival dental plaque and gingivitis","volume":"17","author":"Overholser","year":"1990","journal-title":"J Clin Periodontol"},{"issue":"10","key":"10.14219\/jada.archive.2008.0222_bib11","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1111\/j.1600-051X.2004.00578.x","article-title":"Comparative antiplaque and antigingivitis effectiveness of a chlorhexidine and an essential oil mouthrinse: 6-month clinical trial","volume":"31","author":"Charles","year":"2004","journal-title":"J Clin Periodontol"},{"issue":"3","key":"10.14219\/jada.archive.2008.0222_bib12","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1089\/10755530260128014","article-title":"The effectiveness of processed grapefruit-seed extract as an antibacterial agent, I: an in vitro agar assay","volume":"8","author":"Reagor","year":"2002","journal-title":"J Altern Complement Med"},{"issue":"41","key":"10.14219\/jada.archive.2008.0222_bib13","doi-asserted-by":"crossref","first-page":"6450","DOI":"10.3748\/wjg.v11.i41.6450","article-title":"Grapefruit-seed extract attenuates ethanol- and stress-induced gastric lesions via activation of prostaglandin, nitric oxide and sensory nerve pathways","volume":"11","author":"Brzozowski","year":"2005","journal-title":"World J Gastroenterol"},{"issue":"3","key":"10.14219\/jada.archive.2008.0222_bib14","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1089\/10755530260128023","article-title":"The effectiveness of processed grapefruit-seed extract as an antibacterial agent, II: mechanism of action and in vitro toxicity","volume":"8","author":"Heggers","year":"2002","journal-title":"J Altern Complement Med"},{"issue":"2","key":"10.14219\/jada.archive.2008.0222_bib15","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.fitote.2003.12.010","article-title":"Antioxidant activity of Citrus paradisi seeds glyceric extract","volume":"75","author":"Giamperi","year":"2004","journal-title":"Fitoterapia"},{"issue":"4","key":"10.14219\/jada.archive.2008.0222_bib16","first-page":"97","article-title":"The ability of an herbal mouthrinse to reduce gingival bleeding","volume":"9","author":"Scherer","year":"1998","journal-title":"J Clin Dent"},{"issue":"2","key":"10.14219\/jada.archive.2008.0222_bib17","first-page":"43","article-title":"An in vivo comparison of the antimicrobial activities of three mouthrinses","volume":"9","author":"Gultz","year":"1998","journal-title":"J Clin Dent"},{"issue":"2","key":"10.14219\/jada.archive.2008.0222_bib18","first-page":"46","article-title":"An in vitro investigation of the antimicrobial activity of an herbal mouthrinse","volume":"9","author":"Kaim","year":"1998","journal-title":"J Clin Dent"},{"issue":"7","key":"10.14219\/jada.archive.2008.0222_bib19","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1055\/s-2003-41115","article-title":"Antimicrobial constituents from goldenseal (the rhizomes of Hydrastis canadensis) against selected oral pathogens)","volume":"69","author":"Hwang","year":"2003","journal-title":"Planta Med"},{"issue":"3","key":"10.14219\/jada.archive.2008.0222_bib20","first-page":"243","article-title":"Antimicrobial activity of grapefruit seed and pulp ethanolic extract","volume":"54","author":"Cvetni\u0107","year":"2004","journal-title":"Acta Pharm"},{"issue":"6","key":"10.14219\/jada.archive.2008.0222_bib21","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1016\/S0031-9422(96)00343-3","article-title":"Triterpene alcohols from the flowers of compositae and their anti-inflammatory effects","volume":"43","author":"Akihisa","year":"1996","journal-title":"Phytochemistry"},{"issue":"3\u20134","key":"10.14219\/jada.archive.2008.0222_bib22","first-page":"217","article-title":"Antioxidant properties of some hydroalcoholic plant extracts with antiinflammatory activity","volume":"62","author":"Herold","year":"2003","journal-title":"Roum Arch Microbiol Immunol"},{"issue":"7","key":"10.14219\/jada.archive.2008.0222_bib23","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1111\/j.1365-2036.2004.01902.x","article-title":"Randomized, double-blind, placebo-controlled trial of oral aloe vera gel for active ulcerative colitis","volume":"19","author":"Langmead","year":"2004","journal-title":"Aliment Pharmacol Ther"},{"issue":"5","key":"10.14219\/jada.archive.2008.0222_bib24","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1111\/j.1365-2036.2004.01874.x","article-title":"Anti-inflammatory effects of aloe vera gel in human colorectal mucosa in vitro","volume":"19","author":"Langmead","year":"2004","journal-title":"Aliment Pharmacol Ther"},{"issue":"10","key":"10.14219\/jada.archive.2008.0222_bib25","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1211\/002235702760345464","article-title":"In-vivo and in-vitro anti-inflammatory effect of Echinacea purpurea and Hypericum perforatum","volume":"54","author":"Raso","year":"2002","journal-title":"J Pharm Pharmacol"}],"container-title":["The Journal of the American Dental Association"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002817714640265?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002817714640265?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,7]],"date-time":"2018-10-07T12:58:29Z","timestamp":1538917109000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002817714640265"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,5]]},"references-count":25,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2008,5]]}},"alternative-id":["S0002817714640265"],"URL":"https:\/\/doi.org\/10.14219\/jada.archive.2008.0222","relation":{},"ISSN":["0002-8177"],"issn-type":[{"value":"0002-8177","type":"print"}],"subject":[],"published":{"date-parts":[[2008,5]]}}}