{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T03:04:31Z","timestamp":1787022271988,"version":"build-2736575974"},"reference-count":105,"publisher":"The Korean Spinal Neurosurgery Society","issue":"1","license":[{"start":{"date-parts":[[2020,11,17]],"date-time":"2020-11-17T00:00:00Z","timestamp":1605571200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["e-neurospine.org"],"crossmark-restriction":true},"short-container-title":["Neurospine"],"published-print":{"date-parts":[[2021,3,31]]},"DOI":"10.14245\/ns.2040338.169","type":"journal-article","created":{"date-parts":[[2020,11,17]],"date-time":"2020-11-17T09:18:27Z","timestamp":1605604707000},"page":"23-33","update-policy":"https:\/\/doi.org\/10.14245\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Spontaneous Vertebral Aspergillosis, the State of Art: A Systematic Literature Review"],"prefix":"10.14245","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2475-1955","authenticated-orcid":true,"given":"Andrea","family":"Perna","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5110-8386","authenticated-orcid":true,"given":"Luca","family":"Ricciardi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6913-8460","authenticated-orcid":true,"given":"Massimo","family":"Fantoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0781-3157","authenticated-orcid":true,"given":"Francesco","family":"Taccari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7927-4343","authenticated-orcid":true,"given":"Riccardo","family":"Torelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0928-9213","authenticated-orcid":true,"given":"Domenico Alessandro","family":"Santagada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9841-6431","authenticated-orcid":true,"given":"Caterina","family":"Fumo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3140-5700","authenticated-orcid":true,"given":"Francesco Ciro","family":"Tamburrelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2919-0381","authenticated-orcid":true,"given":"Luca","family":"Proietti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5355","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1086\/588660"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcot.2019.07.002"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1007\/s005860050014"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/s0163-4453(96)92700-0"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2011.03599.x"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1259\/0007-1285-50-600-918"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1979.03630420076025"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1982.03330230050031"},{"key":"ref9","first-page":"295","volume-title":"Aspergillus osteomyelitis. Report of four cases and review of the literature","author":"Tack","year":"1982"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.59.687.43"},{"key":"ref11","first-page":"270","volume-title":"Aspergillus infections of the lumbar disc spaces. Report of three cases","author":"Mawk","year":"1983"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-198466090-00030"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-198511000-00013"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/s0732-8893(85)80008-0"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620x.67b5.3902849"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(85)90349-3"},{"key":"ref17","first-page":"84","volume-title":"Hematogenously acquired Aspergillus vertebral osteomyelitis in seemingly immunocompetent drug addicts","author":"Brown","year":"1987"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/90.3.312"},{"key":"ref19","first-page":"240","volume-title":"Aspergillus discitis. Report of two cases and review of the literature","author":"Holmes","year":"1988"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-199004000-00006"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1227\/00006123-198907000-00025"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-199012000-00027"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-199107000-00010"},{"key":"ref24","first-page":"754","volume-title":"Weekly clinicopathological exercises. Case 11-1991. A 65-year-old man with a vertebral and disk lesion after a pulmonary operation for Aspergillus infection","year":"1991"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/145.6.1483"},{"key":"ref26","first-page":"1512","volume-title":"Aspergillus-induced discitis. A role for itraconazole in therapy?","author":"McGregor","year":"1992"},{"key":"ref27","first-page":"599","volume-title":"Aspergillosis with Aspergillus osteomyelitis and diskitis after heart transplantation: surgical and medical management","author":"Hummel","year":"1993"},{"key":"ref28","first-page":"1287","volume-title":"Aspergillus spondylodiscitis: successful conservative treatment in 9 cases","author":"Cortet","year":"1994"},{"key":"ref29","first-page":"830","volume-title":"Successful medical therapy of Aspergillus osteomyelitis of the spine in an 11-year-old boy with chronic granulomatous disease","author":"Kline","year":"1994"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-199410000-00019"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-199412010-00022"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1177\/088506669501000106"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1007\/bf01781206"},{"key":"ref34","first-page":"678","volume-title":"Aspergillus infection of the neck with an extradural component: an unusual presentation","author":"Lin","year":"1995"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1097\/00019048-199505000-00024"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1016\/0300-2977(95)00048-8"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1186\/s12891-020-03211-7"},{"key":"ref38","first-page":"133","volume-title":"Aspergillus flavus mycetoma and epidural abscess successfully treated with itraconazole","author":"Witzig","year":"1996"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/12.10.2185"},{"key":"ref40","first-page":"381","volume-title":"Fungal spinal osteomyelitis in the immunocompromised patient: MR findings in three cases","author":"Williams","year":"1999"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1086\/514774"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.4065\/74.6.579"},{"key":"ref43","first-page":"123","volume-title":"Aspergillus osteomyelitis after liver transplantation: conservative or surgical treatment?","author":"Tang","year":"2000"},{"key":"ref44","first-page":"107","volume-title":"Spinal aspergillosis in nonimmunocompromised host mimicking Pott\u2019s paraplegia","author":"Ur-Rahman","year":"2000"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.1007\/s001340051299"},{"key":"ref46","doi-asserted-by":"publisher","DOI":"10.1053\/jinf.2000.0673"},{"key":"ref47","doi-asserted-by":"publisher","DOI":"10.1086\/317527"},{"key":"ref48","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2000.15.6.704"},{"key":"ref49","doi-asserted-by":"publisher","DOI":"10.1007\/s002640000205"},{"key":"ref50","first-page":"18","volume-title":"Aspergillus spinal epidural abscess","author":"Gupta","year":"2001"},{"key":"ref51","doi-asserted-by":"publisher","DOI":"10.1016\/s0953-6205(01)00206-0"},{"key":"ref52","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2402209"},{"key":"ref53","first-page":"145","volume-title":"Aspergillus flavus epidural abscess and osteomyelitis in a diabetic patient","author":"Chi","year":"2003"},{"key":"ref54","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-003-0909-3"},{"key":"ref55","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3062.2003.00030.x"},{"key":"ref56","first-page":"13","volume-title":"Para vertebral abscess and rib osteomyelitis due to Aspergillous Fumigatus in a patient with chronic granulomatous disease","author":"Farhoudi","year":"2003"},{"key":"ref57","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2004.08.049"},{"key":"ref58","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2003.05.006"},{"key":"ref59","first-page":"ECR10","volume-title":"Aspergillus fumigatus: a rare cause of vertebral osteomyelitis","author":"Santos","year":"2004"},{"key":"ref60","doi-asserted-by":"publisher","DOI":"10.1016\/j.surneu.2003.06.005"},{"key":"ref61","doi-asserted-by":"publisher","DOI":"10.4103\/0255-0857.16597"},{"key":"ref62","doi-asserted-by":"publisher","DOI":"10.3348\/kjr.2007.8.5.448"},{"key":"ref63","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2007.08.014"},{"key":"ref64","doi-asserted-by":"publisher","DOI":"10.1007\/s11046-016-0007-6"},{"key":"ref65","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2006.08.005"},{"key":"ref66","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-200x.2007.02412.x"},{"key":"ref67","first-page":"49","volume-title":"Multidrug-resistant, progressive, invasive diffuse spinal aspergillosis: case report and review of the literature","author":"Andaluz","year":"2008"},{"key":"ref68","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-008-0789-x"},{"key":"ref69","doi-asserted-by":"publisher","DOI":"10.1002\/dc.21212"},{"key":"ref70","first-page":"52","volume-title":"Aspergillus spondylodiscitis after multivisceral transplantation","author":"Gerlach","year":"2009"},{"key":"ref71","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.080569"},{"key":"ref72","first-page":"e151","volume-title":"Aspergillus vertebral osteomyelitis and epidural abscess","author":"Tew","year":"2009"},{"key":"ref73","doi-asserted-by":"publisher","DOI":"10.3855\/jidc.1001"},{"key":"ref74","doi-asserted-by":"publisher","DOI":"10.3109\/13693780903325290"},{"key":"ref75","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-010-1506-7"},{"key":"ref76","doi-asserted-by":"publisher","DOI":"10.1007\/s00256-010-0967-4"},{"key":"ref77","doi-asserted-by":"publisher","DOI":"10.4103\/0028-3886.72196"},{"key":"ref78","first-page":"1534","volume-title":"A rare, fatal case of invasive spinal aspergillosis in an antiretroviral-naive, HIV-infected man with pre-existing lung colonization","author":"Rossouw","year":"2011"},{"key":"ref79","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciq039"},{"key":"ref80","first-page":"265","volume-title":"Aspergillus fumigatus spondylodiskitis in renal transplant patient: voriconazole experience","author":"Ersoy","year":"2011"},{"key":"ref81","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3062.2011.00599.x"},{"key":"ref82","doi-asserted-by":"publisher","DOI":"10.1097\/inf.0b013e3182309ec0"},{"key":"ref83","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5413.93693"},{"key":"ref84","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2010.09.157"},{"key":"ref85","doi-asserted-by":"publisher","DOI":"10.1177\/0300060513476432"},{"key":"ref86","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-013-0463-6"},{"key":"ref87","doi-asserted-by":"publisher","DOI":"10.4103\/0974-8237.128538"},{"key":"ref88","doi-asserted-by":"publisher","DOI":"10.1111\/1469-0691.12588"},{"key":"ref89","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2014.04.030"},{"key":"ref90","doi-asserted-by":"publisher","DOI":"10.1097\/ipc.0000000000000337"},{"key":"ref91","doi-asserted-by":"publisher","DOI":"10.1097\/inf.0000000000002125"},{"key":"ref92","doi-asserted-by":"publisher","DOI":"10.1177\/0956462419865403"},{"key":"ref93","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofz449"},{"key":"ref94","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2018.08.001"},{"key":"ref95","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2013.12.008"},{"key":"ref96","doi-asserted-by":"publisher","DOI":"10.1111\/1469-0691.12389"},{"key":"ref97","first-page":"2","volume-title":"Epidemiological and clinical features of pyogenic spondylodiscitis","author":"Fantoni","year":"2012"},{"key":"ref98","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-018-5598-9"},{"key":"ref99","doi-asserted-by":"publisher","DOI":"10.14245\/ns.1834938.469"},{"key":"ref100","first-page":"345","volume-title":"Extensive spinal epidural abscesses resolved with minimally invasive surgery: two case reports and review of the recent literature","author":"Proietti","year":"2019"},{"key":"ref101","doi-asserted-by":"publisher","DOI":"10.5704\/moj.1911.007"},{"key":"ref102","doi-asserted-by":"publisher","DOI":"10.1016\/j.jor.2019.11.030"},{"key":"ref103","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciw326"},{"key":"ref104","doi-asserted-by":"publisher","DOI":"10.1080\/13693780802545600"},{"key":"ref105","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.42.3.1376-1378.2004"}],"container-title":["Neurospine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/e-neurospine.org\/upload\/pdf\/ns-2040338-169.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/e-neurospine.org\/journal\/view.php?doi=10.14245\/ns.2040338.169","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/e-neurospine.org\/upload\/pdf\/ns-2040338-169.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,30]],"date-time":"2021-03-30T20:02:33Z","timestamp":1617134553000},"score":1,"resource":{"primary":{"URL":"http:\/\/e-neurospine.org\/journal\/view.php?doi=10.14245\/ns.2040338.169"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,31]]},"references-count":105,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,3]]}},"URL":"https:\/\/doi.org\/10.14245\/ns.2040338.169","relation":{},"ISSN":["2586-6583","2586-6591"],"issn-type":[{"value":"2586-6583","type":"print"},{"value":"2586-6591","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,31]]},"assertion":[{"value":"2020-06-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-07-23","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-11-17","order":2,"name":"published","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-03-31","order":3,"name":"published","label":"Print publication","group":{"name":"publication_history","label":"Publication History"}}]}}