{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T11:32:07Z","timestamp":1781004727456,"version":"3.54.1"},"reference-count":30,"publisher":"The Korean Spinal Neurosurgery Society","issue":"1","license":[{"start":{"date-parts":[[2024,1,31]],"date-time":"2024-01-31T00:00:00Z","timestamp":1706659200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["e-neurospine.org"],"crossmark-restriction":true},"short-container-title":["Neurospine"],"published-print":{"date-parts":[[2024,3,31]]},"abstract":"<jats:p>Objective: To evaluate preoperative disability\u2019s influence on patient-reported outcomes (PROs) following surgery for degenerative spondylolisthesis (DS).Methods: DS patients who underwent surgical intervention were retrospectively identified from a single-surgeon spine registry. Cohorts based on Oswestry Disability Index (ODI) &lt; 41 (milder disability) and \u2265 41 (severe disability) were created. Demographic differences were accounted for with 1:1 propensity score matching. For the matched sample, perioperative and PRO data were additionally collected. PROs assessed included mental health, physical function, pain, and disability. Pre- and up to 2-year postoperative PROs were utilized. Average time to final follow-up was 15.7 \u00b1 8.8 months. Improvements in PROs and minimal clinically important difference (MCID) rates were calculated. Continuous variables were compared through Student t-test and categorical variables were compared through chi-square tests.Results: Altogether, 214 patients were included with 77 in the milder disability group. The severe disability group had worse postoperative day (POD) 1 pain scores and longer hospital stays (p \u2264 0.038, both). The severe disability group reported worse outcomes pre- and postoperatively (p &lt; 0.011, all), but had greater average improvement in 12-item Short Form health survey mental composite score (SF-12 MCS), 9-Item Patient Health Questionnaire (PHQ-9), visual analogue scale (VAS)-back, and ODI by 6 weeks (p \u2264 0.037, all) and PHQ-9, VAS-back and ODI by final follow-up (p \u2264 0.015, all). The severe disability cohort was more likely to achieve MCID for SF-12 MCS, PHQ-9, and ODI (p \u2264 0.003, all).Conclusion: Patients with greater baseline disability report higher POD 1 pain and discharge later than patients with milder disability. While these patients report inferior physical\/mental health before and after surgery, they report greater improvements in mental health and disability postoperatively.<\/jats:p>","DOI":"10.14245\/ns.2347080.540","type":"journal-article","created":{"date-parts":[[2024,1,31]],"date-time":"2024-01-31T14:24:45Z","timestamp":1706711085000},"page":"253-260","update-policy":"https:\/\/doi.org\/10.14245\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Severe Preoperative Disability Is Associated With Greater Mental Health Improvements Following Surgery for Degenerative Spondylolisthesis: A Cohort Matched Analysis"],"prefix":"10.14245","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-1441-8102","authenticated-orcid":true,"given":"Ishan","family":"Khosla","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5953-6094","authenticated-orcid":true,"given":"Fatima  N.","family":"Anwar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7262-8038","authenticated-orcid":true,"given":"Andrea M.","family":"Roca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-0756-2670","authenticated-orcid":true,"given":"Srinath S.","family":"Medakkar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-6883-4593","authenticated-orcid":true,"given":"Alexandra  C.","family":"Loya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-2195-0285","authenticated-orcid":true,"given":"Aayush","family":"Kaul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-6979-0851","authenticated-orcid":true,"given":"Jacob C.","family":"Wolf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3749-9282","authenticated-orcid":true,"given":"Vincent P.","family":"Federico","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6450-2438","authenticated-orcid":true,"given":"Arash J.","family":"Sayari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-8506-0968","authenticated-orcid":true,"given":"Gregory  D.","family":"Lopez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6118-7273","authenticated-orcid":true,"given":"Kern","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5355","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1007\/s00381-012-1942-2"},{"key":"ref2","volume-title":"Lumbar spondylolysis and spondylolisthesis. 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