{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T00:03:03Z","timestamp":1791417783864,"version":"4.3.3"},"reference-count":69,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,9,30]],"date-time":"2024-09-30T00:00:00Z","timestamp":1727654400000},"content-version":"vor","delay-in-days":273,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Prevention of Alzheimer's Disease"],"published-print":{"date-parts":[[2024,1]]},"DOI":"10.14283\/jpad.2023.78","type":"journal-article","created":{"date-parts":[[2023,6,7]],"date-time":"2023-06-07T09:26:29Z","timestamp":1686129989000},"page":"117-129","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"title":["Relationships of Hypnotics with Incident Dementia and Alzheimer's Disease: A Longitudinal Study and Meta-Analysis"],"prefix":"10.1016","volume":"11","author":[{"given":"J.-H.","family":"Hou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.-L.","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.-C.","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.-M.","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.14283\/jpad.2023.78_bib1","unstructured":"Patterson C. World alzheimer report 2018. 2018."},{"key":"10.14283\/jpad.2023.78_bib2","unstructured":"Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019. (2468-2667 (Electronic))."},{"issue":"3","key":"10.14283\/jpad.2023.78_bib3","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1136\/jnnp-2019-321896","article-title":"Sleep problems and risk of all-cause cognitive decline or dementia: an updated systematic review and meta-analysis","volume":"91","author":"Xu","year":"2020","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"8","key":"10.14283\/jpad.2023.78_bib4","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1002\/alz.12117","article-title":"Sleep characteristics and cerebrospinal fluid biomarkers of Alzheimer's disease pathology in cognitively intact older adults: The CABLE study","volume":"16","author":"Xu","year":"2020","journal-title":"Alzheimers Dement"},{"issue":"3","key":"10.14283\/jpad.2023.78_bib5","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1590\/1516-4446-2019-0773","article-title":"The rise and fall and rise of benzodiazepines: a return of the stigmatized and repressed","volume":"42","author":"Balon","year":"2020","journal-title":"Braz J Psychiatry"},{"issue":"19","key":"10.14283\/jpad.2023.78_bib6","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1056\/NEJM197411072911906","article-title":"Drug therapy. Benzodiazepines (first of two parts)","volume":"291","author":"Greenblatt","year":"1974","journal-title":"N Engl J Med"},{"issue":"2","key":"10.14283\/jpad.2023.78_bib7","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1001\/jamapsychiatry.2014.1763","article-title":"Benzodiazepine use in the United States","volume":"72","author":"Olfson","year":"2015","journal-title":"JAMA Psychiatry"},{"issue":"3","key":"10.14283\/jpad.2023.78_bib8","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1017\/S0033291704003897","article-title":"Is benzodiazepine use a risk factor for cognitive decline and dementia? A literature review of epidemiological studies","volume":"35","author":"Verdoux","year":"2005","journal-title":"Psychol Med"},{"issue":"2","key":"10.14283\/jpad.2023.78_bib9","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.jamda.2019.08.006","article-title":"Cognitive Outcomes of Long-term Benzodiazepine and Related Drug (BDZR) Use in People Living With Mild to Moderate Alzheimer's Disease: Results From NILVAD","volume":"21","author":"Dyer","year":"2020","journal-title":"J Am Med Dir Assoc"},{"issue":"1","key":"10.14283\/jpad.2023.78_bib10","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1007\/s13311-019-00801-9","article-title":"Benzodiazepines, z-Hypnotics, and Risk of Dementia: Special Considerations of Half-Lives and Concomitant Use","volume":"17","author":"Tseng","year":"2020","journal-title":"Neurotherapeutics"},{"key":"10.14283\/jpad.2023.78_bib11","doi-asserted-by":"crossref","first-page":"i90","DOI":"10.1136\/bmj.i90","article-title":"Benzodiazepine use and risk of incident dementia or cognitive decline: prospective population based study","volume":"352","author":"Gray","year":"2016","journal-title":"BMJ"},{"issue":"6","key":"10.14283\/jpad.2023.78_bib12","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1176\/appi.ajp.2019.19030315","article-title":"Associations of Benzodiazepines, Z-Drugs, and Other Anxiolytics With Subsequent Dementia in Patients With Affective Disorders: A Nationwide Cohort and Nested Case-Control Study","volume":"177","author":"Osler","year":"2020","journal-title":"Am J Psychiatry"},{"issue":"10357","key":"10.14283\/jpad.2023.78_bib13","volume":"400","year":"2022","journal-title":"The Lancet"},{"issue":"1","key":"10.14283\/jpad.2023.78_bib14","doi-asserted-by":"crossref","first-page":"e12226","DOI":"10.1002\/trc2.12226","article-title":"The Worldwide Alzheimer's Disease Neuroimaging Initiative: ADNI-3 updates and global perspectives","volume":"7","author":"Weber","year":"2021","journal-title":"Alzheimers Dement (N Y)"},{"issue":"7","key":"10.14283\/jpad.2023.78_bib15","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1212\/WNL.34.7.939","article-title":"Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease","volume":"34","author":"McKhann","year":"1984","journal-title":"Neurology"},{"issue":"1","key":"10.14283\/jpad.2023.78_bib16","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1212\/WNL.0b013e318204a397","article-title":"Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort","volume":"76","author":"Kim","year":"2011","journal-title":"Neurology"},{"key":"10.14283\/jpad.2023.78_bib17","doi-asserted-by":"crossref","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"key":"10.14283\/jpad.2023.78_bib18","series-title":"The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses","author":"Wells","year":"2000"},{"issue":"3","key":"10.14283\/jpad.2023.78_bib19","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/0197-2456(86)90046-2","article-title":"Meta-analysis in clinical trials","volume":"7","author":"DerSimonian","year":"1986","journal-title":"Control Clin Trials"},{"issue":"1","key":"10.14283\/jpad.2023.78_bib20","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0047-6374(01)00369-4","article-title":"Uses of DHEA in aging and other disease states","volume":"1","author":"Johnson","year":"2002","journal-title":"Ageing Research Reviews"},{"key":"10.14283\/jpad.2023.78_bib21","doi-asserted-by":"crossref","first-page":"f7450","DOI":"10.1136\/bmj.f7450","article-title":"Converting an odds ratio to a range of plausible relative risks for better communication of research findings","volume":"348","author":"Grant","year":"2014","journal-title":"Bmj"},{"key":"10.14283\/jpad.2023.78_bib22","doi-asserted-by":"crossref","first-page":"d549","DOI":"10.1136\/bmj.d549","article-title":"Interpretation of random effects meta-analyses","volume":"342","author":"Riley","year":"2011","journal-title":"Bmj"},{"issue":"1","key":"10.14283\/jpad.2023.78_bib23","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1002\/jrsm.5","article-title":"Robust variance estimation in metaregression with dependent effect size estimates","volume":"1","author":"Hedges","year":"2010","journal-title":"Res Synth Methods"},{"issue":"3","key":"10.14283\/jpad.2023.78_bib24","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1097\/XEB.0000000000000132","article-title":"The robust error meta-regression method for dose-response meta-analysis","volume":"16","author":"Xu","year":"2018","journal-title":"Int J Evid Based Healthc"},{"issue":"6","key":"10.14283\/jpad.2023.78_bib25","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1007\/s40263-018-0535-3","article-title":"A Systematic Review and Meta-Analysis of the Risk of Dementia Associated with Benzodiazepine Use, After Controlling for Protopathic Bias","volume":"32","author":"Penninkilampi","year":"2018","journal-title":"CNS Drugs"},{"issue":"3","key":"10.14283\/jpad.2023.78_bib26","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.medcle.2020.02.011","article-title":"Association between benzodiazepine use and development of dementia","volume":"156","author":"Aldaz","year":"2021","journal-title":"Medicina Cl\u00ednica (English Edition)"},{"issue":"4","key":"10.14283\/jpad.2023.78_bib27","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1093\/ijnp\/pyab073","article-title":"Benzodiazepine and Z-Drug Use and the Risk of Developing Dementia","volume":"25","author":"Torres-Bondia","year":"2022","journal-title":"Int J Neuropsychopharmacol"},{"issue":"5","key":"10.14283\/jpad.2023.78_bib28","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1093\/gerona\/glab241","article-title":"Use of Benzodiazepines and Risk of Incident Dementia: A Retrospective Cohort Study","volume":"77","author":"Gerlach","year":"2022","journal-title":"J Gerontol A Biol Sci Med Sci"},{"issue":"3","key":"10.14283\/jpad.2023.78_bib29","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1177\/1060028019882037","article-title":"Is Benzodiazepine Use Associated With the Risk of Dementia and Cognitive Impairment-Not Dementia in Older Persons? The Canadian Study of Health and Aging","volume":"54","author":"Nafti","year":"2020","journal-title":"Ann Pharmacother"},{"issue":"2","key":"10.14283\/jpad.2023.78_bib30","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.jamda.2019.05.010","article-title":"Association of Benzodiazepine and Anticholinergic Drug Usage With Incident Dementia: A Prospective Cohort Study of Community-Dwelling Older Adults","volume":"21","author":"Hafdi","year":"2020","journal-title":"J Am Med Dir Assoc"},{"issue":"2","key":"10.14283\/jpad.2023.78_bib31","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.jamda.2019.08.017","article-title":"Uncertain Association Between Benzodiazepine Use and the Risk of Dementia: A Cohort Study","volume":"21","author":"Baek","year":"2020","journal-title":"J Am Med Dir Assoc"},{"issue":"7","key":"10.14283\/jpad.2023.78_bib32","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1093\/aje\/kwz073","article-title":"History of Benzodiazepine Prescriptions and Risk of Dementia: Possible Bias Due to Prevalent Users and Covariate Measurement Timing in a Nested Case-Control Study","volume":"188","author":"Richardson","year":"2019","journal-title":"Am J Epidemiol"},{"issue":"1","key":"10.14283\/jpad.2023.78_bib33","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1186\/s12877-019-1280-2","article-title":"Anticholinergic and benzodiazepine medication use and risk of incident dementia: a UK cohort study","volume":"19","author":"Grossi","year":"2019","journal-title":"BMC Geriatr"},{"issue":"2","key":"10.14283\/jpad.2023.78_bib34","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1111\/acps.12909","article-title":"The risk of Alzheimer's disease associated with benzodiazepines and related drugs: a nested case-control study","volume":"138","author":"Tapiainen","year":"2018","journal-title":"Acta Psychiatr Scand"},{"issue":"9","key":"10.14283\/jpad.2023.78_bib35","doi-asserted-by":"crossref","first-page":"e0204413","DOI":"10.1371\/journal.pone.0204413","article-title":"Use of sedative-hypnotics and the risk of Alzheimer's dementia: A retrospective cohort study","volume":"13","author":"Lee","year":"2018","journal-title":"PLoS One"},{"issue":"5","key":"10.14283\/jpad.2023.78_bib36","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1111\/jgs.14756","article-title":"PTSD, Psychotropic Medication Use, and the Risk of Dementia Among US Veterans: A Retrospective Cohort Study","volume":"65","author":"Mawanda","year":"2017","journal-title":"J Am Geriatr Soc"},{"issue":"5","key":"10.14283\/jpad.2023.78_bib37","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1111\/psyg.12239","article-title":"Association between high cumulative dose of benzodiazepine in Chinese patients and risk of dementia: a preliminary retrospective case-control study","volume":"17","author":"Chan","year":"2017","journal-title":"Psychogeriatrics"},{"issue":"5","key":"10.14283\/jpad.2023.78_bib38","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1016\/j.jalz.2015.10.006","article-title":"Benzodiazepine, psychotropic medication, and dementia: A population-based cohort study","volume":"12","author":"Shash","year":"2016","journal-title":"Alzheimers Dement"},{"key":"10.14283\/jpad.2023.78_bib39","doi-asserted-by":"crossref","first-page":"g5205","DOI":"10.1136\/bmj.g5205","article-title":"Benzodiazepine use and risk of Alzheimer's disease: case-control study","volume":"349","author":"Billioti de Gage","year":"2014","journal-title":"BMJ"},{"issue":"10","key":"10.14283\/jpad.2023.78_bib40","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1136\/jech-2011-200314","article-title":"Benzodiazepine use and risk of dementia: evidence from the Caerphilly Prospective Study (CaPS)","volume":"66","author":"Gallacher","year":"2012","journal-title":"J Epidemiol Community Health"},{"issue":"7","key":"10.14283\/jpad.2023.78_bib41","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1097\/JGP.0b013e3181a65210","article-title":"The association between dementia and long-term use of benzodiazepine in the elderly: nested case-control study using claims data","volume":"17","author":"Wu","year":"2009","journal-title":"Am J Geriatr Psychiatry"},{"issue":"3","key":"10.14283\/jpad.2023.78_bib42","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/S0895-4356(01)00453-X","article-title":"Benzodiazepine use and risk of dementia: a nested case-control study","volume":"55","author":"Lagnaoui","year":"2002","journal-title":"J Clin Epidemiol"},{"issue":"11","key":"10.14283\/jpad.2023.78_bib43","doi-asserted-by":"crossref","first-page":"2488","DOI":"10.1111\/jgs.15018","article-title":"The Association Between the Use of Zolpidem and the Risk of Alzheimer's Disease Among Older People","volume":"65","author":"Cheng","year":"2017","journal-title":"J Am Geriatr Soc"},{"key":"10.14283\/jpad.2023.78_bib44","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.jad.2020.08.025","article-title":"Association between concurrent antidepressant and hypnotic treatment and the risk of dementia: A nationwide cohort study","volume":"277","author":"Lin","year":"2020","journal-title":"J Affect Disord"},{"issue":"12","key":"10.14283\/jpad.2023.78_bib45","doi-asserted-by":"crossref","first-page":"2271","DOI":"10.1016\/j.euroneuro.2015.09.011","article-title":"Hypnotics use but not insomnia increased the risk of dementia in traumatic brain injury patients","volume":"25","author":"Chiu","year":"2015","journal-title":"European Neuropsychopharmacology"},{"key":"10.14283\/jpad.2023.78_bib46","article-title":"Sleep medication use and incident dementia in a nationally representative sample of older adults in the US","author":"Robbins","year":"2020","journal-title":"Sleep Med"},{"issue":"2","key":"10.14283\/jpad.2023.78_bib47","doi-asserted-by":"crossref","first-page":"801","DOI":"10.3233\/JAD-151006","article-title":"Regular Benzodiazepine and Z-Substance Use and Risk of Dementia: An Analysis of German Claims Data","volume":"54","author":"Gomm","year":"2016","journal-title":"J Alzheimers Dis"},{"issue":"1","key":"10.14283\/jpad.2023.78_bib48","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/s13195-021-00952-y","article-title":"Complaints of daytime sleepiness, insomnia, hypnotic use, and risk of dementia: a prospective cohort study in the elderly","volume":"14","author":"Cavailles","year":"2022","journal-title":"Alzheimers Res Ther"},{"issue":"2","key":"10.14283\/jpad.2023.78_bib49","doi-asserted-by":"crossref","first-page":"125","DOI":"10.7326\/M15-2175","article-title":"Management of Chronic Insomnia Disorder in Adults: A Clinical Practice Guideline From the American College of Physicians","volume":"165","author":"Qaseem","year":"2016","journal-title":"Ann Intern Med"},{"issue":"2","key":"10.14283\/jpad.2023.78_bib50","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1002\/wps.20881","article-title":"Efficacy and acceptability of pharmacological, psychosocial, and brain stimulation interventions in children and adolescents with mental disorders: an umbrella review","volume":"20","author":"Correll","year":"2021","journal-title":"World Psychiatry"},{"issue":"3","key":"10.14283\/jpad.2023.78_bib51","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1002\/wps.20674","article-title":"The assessment and management of insomnia: an update","volume":"18","author":"Krystal","year":"2019","journal-title":"World Psychiatry"},{"key":"10.14283\/jpad.2023.78_bib52","doi-asserted-by":"crossref","first-page":"101404","DOI":"10.1016\/j.smrv.2020.101404","article-title":"The effect of cognitive behavioural therapy for insomnia on sedative-hypnotic use: A narrative review","volume":"56","author":"Sweetman","year":"2021","journal-title":"Sleep Med Rev"},{"issue":"21","key":"10.14283\/jpad.2023.78_bib53","first-page":"7526","article-title":"Effects of melatonin on expressions of \u03b2-amyloid protein and S100\u03b2 in rats with senile dementia","volume":"22","author":"Fang","year":"2018","journal-title":"Eur Rev Med Pharmacol Sci"},{"issue":"4","key":"10.14283\/jpad.2023.78_bib54","doi-asserted-by":"crossref","first-page":"e12774","DOI":"10.1111\/jpi.12774","article-title":"Melatonin ameliorates cognitive deficits through improving mitophagy in a mouse model of Alzheimer's disease","volume":"71","author":"Chen","year":"2021","journal-title":"J Pineal Res"},{"issue":"5","key":"10.14283\/jpad.2023.78_bib55","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1159\/000524400","article-title":"Benzodiazepines Remain Important Therapeutic Options in Psychiatric Practice","volume":"91","author":"Dubovsky","year":"2022","journal-title":"Psychother Psychosom"},{"key":"10.14283\/jpad.2023.78_bib56","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jad.2019.05.059","article-title":"The effect of short-term use of benzodiazepines on cognitive function of major depressive disorder patients being treated with antidepressants","volume":"256","author":"Duan","year":"2019","journal-title":"J Affect Disord"},{"issue":"7","key":"10.14283\/jpad.2023.78_bib57","doi-asserted-by":"crossref","first-page":"611","DOI":"10.2174\/138920011796504473","article-title":"Age-related changes in pharmacodynamics: focus on drugs acting on central nervous and cardiovascular systems","volume":"12","author":"Trifir\u00f2","year":"2011","journal-title":"Curr Drug Metab"},{"issue":"5","key":"10.14283\/jpad.2023.78_bib58","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1176\/ajp.149.5.587","article-title":"Gender differences in pharmacokinetics and pharmacodynamics of psychotropic medication","volume":"149","author":"Yonkers","year":"1992","journal-title":"Am J Psychiatry"},{"key":"10.14283\/jpad.2023.78_bib59","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.pbb.2018.07.005","article-title":"Chronic benzodiazepine suppresses translocator protein and elevates amyloid beta in mice","volume":"172","author":"Tan","year":"2018","journal-title":"Pharmacol Biochem Behav"},{"issue":"1","key":"10.14283\/jpad.2023.78_bib60","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1073\/pnas.012467899","article-title":"Functional MRI detection of pharmacologically induced memory impairment","volume":"99","author":"Sperling","year":"2002","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"11","key":"10.14283\/jpad.2023.78_bib61","doi-asserted-by":"crossref","first-page":"2315","DOI":"10.1038\/npp.2013.137","article-title":"Allosteric modulation of GABA(A) receptor subtypes:effects on visual recognition and visuospatial working memory in rhesus monkeys [corrected]","volume":"38","author":"Soto","year":"2013","journal-title":"Neuropsychopharmacology"},{"issue":"45","key":"10.14283\/jpad.2023.78_bib62","doi-asserted-by":"crossref","first-page":"18595","DOI":"10.1073\/pnas.1204994109","article-title":"Benzodiazepine treatment induces subtype-specific changes in GABA(A) receptor trafficking and decreases synaptic inhibition","volume":"109","author":"Jacob","year":"2012","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"10","key":"10.14283\/jpad.2023.78_bib63","doi-asserted-by":"crossref","first-page":"3662","DOI":"10.1073\/pnas.0307231101","article-title":"Tonic inhibition in mouse hippocampal CA1 pyramidal neurons is mediated by alpha5 subunit-containing gamma-aminobutyric acid type A receptors","volume":"101","author":"Caraiscos","year":"2004","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"6920","key":"10.14283\/jpad.2023.78_bib64","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1038\/nature01280","article-title":"Coupling of agonist binding to channel gating in the GABA(A) receptor","volume":"421","author":"Kash","year":"2003","journal-title":"Nature"},{"issue":"2","key":"10.14283\/jpad.2023.78_bib65","first-page":"214","article-title":"Benzodiazepine pharmacology and central nervous system-mediated effects","volume":"13","author":"Griffin","year":"2013","journal-title":"Ochsner J"},{"issue":"1","key":"10.14283\/jpad.2023.78_bib66","doi-asserted-by":"crossref","first-page":"9","DOI":"10.3988\/jcn.2019.15.1.9","article-title":"Risk of Dementia in Long-Term Benzodiazepine Users: Evidence from a Meta-Analysis of Observational Studies","volume":"15","author":"He","year":"2019","journal-title":"J Clin Neurol"},{"issue":"12","key":"10.14283\/jpad.2023.78_bib67","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1001\/jama.288.12.1475","article-title":"Prevalence of neuropsychiatric symptoms in dementia and mild cognitive impairment: results from the cardiovascular health study","volume":"288","author":"Lyketsos","year":"2002","journal-title":"Jama"},{"issue":"4","key":"10.14283\/jpad.2023.78_bib68","doi-asserted-by":"crossref","first-page":"584","DOI":"10.4088\/JCP.08m04181","article-title":"Mild behavioral impairment and risk of dementia: a prospective cohort study of 358 patients","volume":"70","author":"Taragano","year":"2009","journal-title":"J Clin Psychiatry"},{"issue":"11","key":"10.14283\/jpad.2023.78_bib69","doi-asserted-by":"crossref","first-page":"e49113","DOI":"10.1371\/journal.pone.0049113","article-title":"Risk of dementia in patients with insomnia and long-term use of hypnotics: a population-based retrospective cohort study","volume":"7","author":"Chen","year":"2012","journal-title":"PLoS One"}],"container-title":["The Journal of Prevention of Alzheimer's Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2274580724001158?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2274580724001158?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,9]],"date-time":"2025-01-09T23:38:14Z","timestamp":1736465894000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2274580724001158"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":69,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["S2274580724001158"],"URL":"https:\/\/doi.org\/10.14283\/jpad.2023.78","relation":{},"ISSN":["2274-5807"],"issn-type":[{"value":"2274-5807","type":"print"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Relationships of Hypnotics with Incident Dementia and Alzheimer's Disease: A Longitudinal Study and Meta-Analysis","name":"articletitle","label":"Article Title"},{"value":"The Journal of Prevention of Alzheimer's Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.14283\/jpad.2023.78","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2023 THE AUTHORS. Published by Elsevier Masson SAS on behalf of SERDI Publisher. Published by Elsevier Masson SAS","name":"copyright","label":"Copyright"}]}}