{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T14:11:11Z","timestamp":1753884671724,"version":"3.41.2"},"reference-count":40,"publisher":"Open Access Pub","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAA"],"abstract":"<jats:p>The aim of the study was to evaluate the antioxidant potential of Biofield Energy Healing (the Trivedi Effect\u00ae) based test formulation using TNBS-induced colitis animal model. Each ingredient of the test formulation was divided into two parts. One part was denoted as the control without any Biofield Energy Treatment, while the other part was treated with Biofield Energy Treatment by Mr. Mahendra Kumar Trivedi and defined as the Biofield Energy Treated test formulation. The colon tissue was used for the estimation of anti-oxidation activity for catalase (CAT), glutathione (GSH), lipid peroxidation (LPO) product, myeloperoxidase (MPO), superoxide dismutase (SOD), and glutathione peroxidase (GPx) using standard procedure. The antioxidant results showed that the CAT level was significantly increased by 95.4% (p\u22640.001), 72.3%, 47.6%, and 13.9% in the Biofield Energy Treated test formulation (G5), Biofield treatment per se to animals (-15 days)(G6), Biofield Energy Treatment per se to animals plus Biofield Energy Treated test formulation (-15 day) (G8), and Biofield Energy Treatment per se to animals plus untreated test formulation (G9) groups, respectively as compared to the untreated test formulation group (G4). Further, colon GSH activity was found to be significantly increased by 23.2% (p\u22640.05) 15.4%, and 15.5%, in G5, G6, and G9 groups, respectively with respect to G2 group. In addition, colon LPO activity data suggested that it was decreased by 12%, 17%, 18%, and 19.1% in G5, G6, Biofield Energy Treated test formulation (-15 day) (G7), and G8 groups, respectively, as compared with the G2 group. The level of MPO showed a significant (p\u22640.001) reduced level by 27.9%, 22%, 14.5%, 16.6%, and 25.3% in G5, G6, G7, G8, and G9 groups, respectively as compared with the G2 group. The level of colon SOD was increased by 16.7% and 14.2% in the G5 and G9 groups, respectively as compared with the untreated test formulation, G4 group. Colon GPx level was increased by 177.6%, 71.4%, 71.4%, 161.2%, and 114.3% in G5, G6, G7, G8, and G9 groups, respectively as compared with the G2 group. Thus, it can be concluded that the Trivedi Effect\u00ae-Consciousness Energy Healing based test formulation and Biofield Energy per se has significant colon anti-oxidation profile, which can be used to improve many autoimmune and inflammatory diseases, stress management and prevention, and anti-aging by improving overall health.<\/jats:p>","DOI":"10.14302\/issn.2471-2140.jaa-21-3704","type":"journal-article","created":{"date-parts":[[2021,5,3]],"date-time":"2021-05-03T14:49:31Z","timestamp":1620053371000},"page":"29-40","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of Anti-oxidation and Therapeutic Effect of Biofield Energy Healing Based Novel Test Formulation Using TNBS (Tri Nitro Benzene Sulfonic Acid) - Induced Ulcerative Colitis in Sprague Dawley Rats"],"prefix":"10.14302","volume":"2","author":[{"given":"Mahendra Kumar","family":"Trivedi","sequence":"first","affiliation":[{"name":"Trivedi Global, Inc., Henderson, Nevada, USA"}]},{"given":"Snehasis","family":"Jana","sequence":"additional","affiliation":[{"name":"Trivedi Science Research Laboratory Pvt. Ltd., Thane-West, Maharashtra, India"}]}],"member":"5410","published-online":{"date-parts":[[2021,2,19]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"1.Dylag K, Hubalewska-Mazgaj M, Surmiak M, Szmyd J, Brzozowski T. (2014) Probiotics in the mechanism of protection against gut inflammation and therapy of gastrointestinal disorders. , Curr Pharm Des 20, 1149-1155.","DOI":"10.2174\/13816128113199990422"},{"key":"ref1","doi-asserted-by":"crossref","unstructured":"2.Wang Y, Wu Y, Wang Y, Xu H, Mei X et al. (2017) Antioxidant properties of probiotic bacteria. , Nutrients 9(5), 521.","DOI":"10.3390\/nu9050521"},{"key":"ref2","doi-asserted-by":"publisher","unstructured":"3.Poplawski T, Chojnacki C, Czubatka A, Klupinska G, Chojnacki J et al. (2013) pyloriinfection and antioxidants can modulate the genotoxic effects of heterocyclic amines in gastric mucosa cells. , Mol Biol Rep 40, 5205-5212.","DOI":"10.1007\/s11033-013-2622-3"},{"key":"ref3","doi-asserted-by":"publisher","unstructured":"4.Greenway F, Wang S, Heiman M. (2014) A novel cobiotic containing a prebiotic and an antioxidant augments the glucose control and gastrointestinal tolerability of metformin: A case report. , Benef Microbes 5, 29-32.","DOI":"10.3920\/bm2012.0063"},{"key":"ref4","doi-asserted-by":"publisher","unstructured":"5.Serban D E. (2015) Microbiota in inflammatory bowel disease pathogenesis and therapy: Is it all about diet?. , Nutr Clin Pract 30, 760-779.","DOI":"10.1177\/0884533615606898"},{"key":"ref5","doi-asserted-by":"publisher","unstructured":"6.Carding S, Verbeke K, Vipond D T, Corfe B M, Owen L J. (2015) Dysbiosis of the gut microbiota in disease. , Microb Ecol Health Dis 26, 26191.","DOI":"10.3402\/mehd.v26.26191"},{"key":"ref6","doi-asserted-by":"publisher","unstructured":"7.Thomas K J, Nicholl J P, Coleman P. (2001) Use and expenditure on complementary medicine in England: A population based survey. , Complement Ther Med 9, 2-11.","DOI":"10.1054\/ctim.2000.0407"},{"key":"ref7","doi-asserted-by":"publisher","unstructured":"8.Manya K, Champion B, Dunning T. (2012) The use of complementary and alternative medicine among people living with diabetes in Sydney. , BMC Complement Altern Med 12, 2-10.","DOI":"10.1186\/1472-6882-12-2"},{"key":"ref8","doi-asserted-by":"crossref","unstructured":"9.Astin J A, Pelletier K R, Marie A, Haskell W L. (2000) Complementary and alternative medicine use among elderly persons: One-year analysis of a blue shield medicare supplement. , J Gerontol A Biol Sci Med Sci 55, 4-9.","DOI":"10.1093\/gerona\/55.1.M4"},{"key":"ref9","doi-asserted-by":"publisher","unstructured":"10.Movaffaghi Z, Farsi M. (2009) Biofield therapies: Biophysical basis and biological regulations?. , Complement Ther Clin Pr 15, 35-37.","DOI":"10.1016\/j.ctcp.2008.07.001"},{"key":"ref10","doi-asserted-by":"publisher","unstructured":"11.Berman J D, Straus S E. (2004) Implementing a research agenda for complementary and alternative medicine. , Annu Rev Med 55, 239-254.","DOI":"10.1146\/annurev.med.55.091902.103657"},{"key":"ref11","unstructured":"12.Frass M, Strassl R P, Friehs H, Mullner M, Kundi M et al. (2012) Use and acceptance of complementary and alternative medicine among the general population and medical personnel: A systematic review. , Ochsner J 12, 45-56."},{"key":"ref12","doi-asserted-by":"publisher","unstructured":"13.Sancier K M, Holman D. (2004) Commentary: Multifaceted health benefits of medical qigong. , J Altern Comp Med10: 163-165.","DOI":"10.1089\/107555304322849084"},{"key":"ref13","doi-asserted-by":"publisher","unstructured":"14.Trivedi M K, TRR Mohan. (2016) Biofield energy signals, energy transmission and neutrinos. , American Journal of Modern Physics 5, 172-176.","DOI":"10.11648\/j.ajmp.20160506.12"},{"key":"ref14","doi-asserted-by":"publisher","unstructured":"15.Trivedi M K, Branton A, Trivedi D, Nayak G, Mondal S C et al. (2015) Antimicrobial sensitivity, biochemical characteristics and biotyping ofStaphylococcus saprophyticus: An impact of biofield energy treatment. , J Women\u2019s Health Care 4, 271.","DOI":"10.4172\/2167-0420.1000271"},{"key":"ref15","doi-asserted-by":"publisher","unstructured":"16.Trivedi M K, Patil S, Shettigar H, Mondal S C, Jana.S (2015)In vitroevaluation of biofield treatment onEnterobacter cloacae: Impact on antimicrobial susceptibility and biotype. , J Bacteriol Parasitol 6, 241.","DOI":"10.4172\/2155-9597.1000241"},{"key":"ref16","doi-asserted-by":"publisher","unstructured":"17.Trivedi M K, Patil S, Shettigar H, Mondal S C, Jana S. (2015) Evaluation of biofield modality on viral load of Hepatitis B and C Viruses. , J Antivir Antiretrovir 7, 83-88.","DOI":"10.4172\/jaa.1000123"},{"key":"ref17","doi-asserted-by":"publisher","unstructured":"18.Trivedi M K, Branton A, Trivedi D, Nayak G, Mondal S C et al. (2015) Evaluation of antibiogram, genotype and phylogenetic analysis of biofield treatedNocardiaotitidis. , Biol Syst Open Access 4, 143.","DOI":"10.4172\/2329-6577.1000143"},{"key":"ref18","doi-asserted-by":"publisher","unstructured":"19.Trivedi M K, Branton A, Trivedi D, Nayak G, Charan S et al. (2015) Phenotyping and 16S rDNA analysis after biofield treatment onCitrobacterbraakii: A urinary pathogen. , J Clin Med Genom 3, 129.","DOI":"10.4172\/2332-0672.1000129"},{"key":"ref19","unstructured":"20.Peoples J J, Trivedi M K, Branton A, Trivedi D, Nayak G et al. (2017) Skin rejuvenating effect of consciousness energy healing treatment based herbomineral formulation. , American Journal of Plant Biology 2, 77-87."},{"key":"ref20","doi-asserted-by":"publisher","unstructured":"21.Smith D M, Trivedi M K, Branton A, Trivedi D, Nayak G et al. (2017) Skin protective activity of consciousness energy healing treatment based herbomineral formulation. , Journal of Food and Nutrition Sciences 5, 86-95.","DOI":"10.11648\/j.jfns.20170503.15"},{"key":"ref21","doi-asserted-by":"crossref","unstructured":"22.Weekes B A, Trivedi M K, Branton A, Trivedi D, Nayak G et al. (2018) an alternative approach for the management of bone health: Role of biofield energy healing treated vitamin D3. , American Journal of Internal Medicine 6, 1-9.","DOI":"10.11648\/j.ajim.20180601.11"},{"key":"ref22","doi-asserted-by":"publisher","unstructured":"23.Piedad R B, Trivedi M K, Branton A, Trivedi D, Nayak G et al. (2018) Exploring the effects of biofield energy treated vitamin D3 on bone health parameters in MG-63 cell line. , International Journal of Food Science and Biotechnology 3, 15-22.","DOI":"10.14302\/issn.2379-7835.ijn-18-2301"},{"key":"ref23","doi-asserted-by":"publisher","unstructured":"24.Patric E, Trivedi M K, Branton A, Trivedi D, Nayak G et al. (2018) The influence of biofield energy treated vitamin D3 on bone health and its health consequences in MG-63 cell-line. , Advances in Bioscience and Bioengineering 6, 1-9.","DOI":"10.11648\/j.abb.20180601.11"},{"key":"ref24","doi-asserted-by":"publisher","unstructured":"25.Trivedi M K, Branton A, Trivedi D, Nayak G, Gangwar M et al. (2015) Analysis of genetic diversity using simple sequence repeat (SSR) markers and growth regulator response in biofield treated cotton (GossypiumhirsutumL.). , American Journal of Agriculture and Forestry 3, 216-221.","DOI":"10.11648\/j.ajaf.20150305.17"},{"key":"ref25","doi-asserted-by":"publisher","unstructured":"26.Trivedi M K, Branton A, Trivedi D, Nayak G, Gangwar M et al. (2015) Evaluation of vegetative growth parameters in biofield treated bottle gourd (Lagenaria siceraria) and okra (Abelmoschus esculentus). , International Journal of Nutrition and Food Sciences 4, 688-694.","DOI":"10.11648\/j.ijnfs.20150406.24"},{"key":"ref26","doi-asserted-by":"publisher","unstructured":"27.Trivedi M K, Branton A, Trivedi D, Nayak G, Balmer A J et al. (2016) Evaluation of pro-inflammatory cytokines expression in mouse splenocytes after incubation with biofield treated herbomineral formulation: Effect of biofield energy healing treatment - The Trivedi Effect\u00ae. , American Journal of Biomedical and Life Sciences 4, 87-97.","DOI":"10.11648\/j.ajbls.20160406.12"},{"key":"ref27","doi-asserted-by":"publisher","unstructured":"28.Trivedi M K, Branton A, Trivedi D, Nayak G, Ellis M P et al. (2016) Evaluation of pro-inflammatory cytokines expression in mouse splenocytes after co-incubation with the biofield energy treated formulation: Impact of the Trivedi Effect\u00ae. , International Journal of Biomedical Science and Engineering 4, 40-49.","DOI":"10.11648\/j.ijbse.20160405.11"},{"key":"ref28","doi-asserted-by":"publisher","unstructured":"29.Trivedi M K, Patil S, Shettigar H, Bairwa K, Jana S. (2015) Spectroscopic characterization of biofield treated metronidazole and tinidazole. , Med Chem 5, 340-344.","DOI":"10.4172\/2161-0444.1000283"},{"key":"ref29","doi-asserted-by":"publisher","unstructured":"30.Trivedi M K, Patil S, Shettigar H, Bairwa K, Jana S. (2015) Effect of biofield treatment on spectral properties of paracetamol and piroxicam. , Chem Sci J 6, 98.","DOI":"10.4172\/2150-3494.100098"},{"key":"ref30","doi-asserted-by":"publisher","unstructured":"31.Trivedi M K, Tallapragada R M, Branton A, Trivedi D, Nayak G et al. (2015) Evaluation of atomic, physical, and thermal properties of bismuth oxide powder: An impact of biofield energy treatment. , American Journal of Nano Research and Applications 3, 94-98.","DOI":"10.4172\/2169-0316.1000177"},{"key":"ref31","doi-asserted-by":"publisher","unstructured":"32.Trivedi M K, Patil S, Nayak G, Jana S, Latiyal O. (2015) Influence of biofield treatment on physical, structural and spectral properties of boron nitride. , J Material Sci Eng 4, 181.","DOI":"10.4172\/2169-0022.1000181"},{"key":"ref32","doi-asserted-by":"crossref","unstructured":"33.Djordjevi\u0107 V B. (2004) Free radicals in cell biology. , Int Rev Cytol 237, 57-89.","DOI":"10.1016\/S0074-7696(04)37002-6"},{"key":"ref33","unstructured":"34.Loguercio C, M Di Pierro. (1999) The role of glutathione in the gastrointestinal tract: A review. , Ital J Gastroenterol Hepatol 31, 401-407."},{"key":"ref34","doi-asserted-by":"publisher","unstructured":"35.Podrez E A, Abu-Soud H M, Hazen S L. (2008) Myeloperoxidase-generated oxidants and atherosclerosis. , Free Radic Biol Med 28, 1717-1725.","DOI":"10.1016\/s0891-5849(00)00229-x"},{"key":"ref35","doi-asserted-by":"crossref","unstructured":"36.Banniste J, Bannister W, Rotilio G. (1987) Aspects of the structure, function, and applications of superoxide dismutase. , CRC Crit Rev Biochem22: 111-180.","DOI":"10.3109\/10409238709083738"},{"key":"ref36","doi-asserted-by":"publisher","unstructured":"37.Balmus I M, Ciobica A, Trifan A, Stanciu C. (2016) The implications of oxidative stress and antioxidant therapies in Inflammatory Bowel Disease: Clinical aspects and animal models. , Saudi J Gastroenterol 22, 3-17.","DOI":"10.4103\/1319-3767.173753"},{"key":"ref37","doi-asserted-by":"crossref","unstructured":"38.Vasilaki A T, McMillan D C. (2011) Lipid Peroxidation. In: Schwab M. (eds) Encyclopedia of Cancer. , Berlin, Heidelberg","DOI":"10.1007\/978-3-642-16483-5_3373"},{"key":"ref38","doi-asserted-by":"publisher","unstructured":"39.M\u00f8ller P, Loft S. (2010) Oxidative Damage to DNA and lipids as biomarkers of exposure to air pollution. , Environ Health Perspect 118, 1126-1136.","DOI":"10.1289\/ehp.0901725"},{"key":"ref39","doi-asserted-by":"publisher","unstructured":"40.Negre-Salvayre A, Coatrieux C, Ingueneau C, Salvayre R. (2008) Advanced lipid peroxidation end products in oxidative damage to proteins. Potential role in diseases and therapeutic prospects for the inhibitors. , Br J Pharmacol 153, 6-20.","DOI":"10.1038\/sj.bjp.0707395"}],"container-title":["Journal of Antioxidant Activity"],"original-title":[],"link":[{"URL":"https:\/\/openaccesspub.org\/jaa\/article\/1577","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,3]],"date-time":"2021-05-03T14:57:44Z","timestamp":1620053864000},"score":1,"resource":{"primary":{"URL":"https:\/\/openaccesspub.org\/jaa\/article\/1577"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,19]]},"references-count":40,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2020,3,11]]}},"URL":"https:\/\/doi.org\/10.14302\/issn.2471-2140.jaa-21-3704","relation":{},"ISSN":["2471-2140"],"issn-type":[{"type":"electronic","value":"2471-2140"}],"subject":[],"published":{"date-parts":[[2021,2,19]]},"article-number":"1577"}}