{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T15:56:49Z","timestamp":1786550209405,"version":"build-2736575974"},"reference-count":19,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","license":[{"start":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T00:00:00Z","timestamp":1556668800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACG Case Rep J","ACG Case Reports Journal"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Eosinophilic esophagitis (EoE) and type 2B von Willebrand disease (vWD) are both rare diseases, and the co-occurrence is unlikely. Patients with EoE often need recurrent endoscopic dilations and esophageal biopsies, and the safety of these procedures in the setting of bleeding disorders is not well described in the literature. We describe successful management strategies in a patient with co-existing EoE and type 2B vWD who required multiple dilations and biopsies. This approach might be used for patients with other esophageal disorders and type 2B vWD as well.<\/jats:p>","DOI":"10.14309\/crj.0000000000000069","type":"journal-article","created":{"date-parts":[[2019,5,14]],"date-time":"2019-05-14T17:52:10Z","timestamp":1557856330000},"page":"e00069","source":"Crossref","is-referenced-by-count":1,"title":["Rare Co-occurrence of Eosinophilic Esophagitis and Type 2B von Willebrand Disease: Implications for Endoscopic Surveillance and Esophageal Dilation"],"prefix":"10.14309","volume":"6","author":[{"given":"S. Ryanne","family":"Corder","sequence":"first","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Department of Medicine, Center for Esophageal Diseases and Swallowing, and Center for Gastrointestinal Biology and Disease, Chapel Hill, NC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brent W.","family":"Weston","sequence":"additional","affiliation":[{"name":"Division of Hematology and Oncology, Department of Pediatrics, University of North Carolina School of Medicine, Chapel Hill, NC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evan S.","family":"Dellon","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Department of Medicine, Center for Esophageal Diseases and Swallowing, and Center for Gastrointestinal Biology and Disease, Chapel Hill, NC"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2019,5,14]]},"reference":[{"key":"R1-20230717","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1053\/j.gastro.2017.06.067","article-title":"Epidemiology and natural history of eosinophilic esophagitis","volume":"154","author":"Dellon","year":"2018","journal-title":"Gastroenterology"},{"key":"R2-20230717","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1038\/ajg.2013.71","article-title":"ACG clinical guideline: Evidenced based approach to the diagnosis and management of esophageal eosinophilia and eosinophilic esophagitis (EoE)","volume":"108","author":"Dellon","year":"2013","journal-title":"Am J Gastroenterol"},{"key":"R3-20230717","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1053\/j.gastro.2018.07.009","article-title":"Updated international consensus diagnostic criteria for eosinophilic esophagitis: Proceedings of the AGREE 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new variant of von Willebrand's disease (type I Padua): Doublet-organized plasma von Willebrand factor oligomers in the presence of all size multimers","volume":"26","author":"Casonato","year":"1994","journal-title":"Haematologia (Budap)"},{"key":"R11-20230717","doi-asserted-by":"crossref","first-page":"1859","DOI":"10.1182\/blood.V74.5.1859.1859","article-title":"DDAVP for type IIB von Willebrand disease","volume":"74","author":"Fowler","year":"1989","journal-title":"Blood"},{"key":"R12-20230717","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1111\/hae.13165","article-title":"Laboratory monitoring of replacement therapy for major surgery in von Willebrand disease","volume":"23","author":"Mannucci","year":"2017","journal-title":"Haemophilia"},{"key":"R13-20230717","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1182\/blood-2014-08-551960","article-title":"How I treat type 2 variant forms of von Willebrand 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