{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T15:56:51Z","timestamp":1786550211372,"version":"build-2736575974"},"reference-count":16,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","license":[{"start":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T00:00:00Z","timestamp":1556668800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACG Case Rep J","ACG Case Reports Journal"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Occult Kaposi's sarcoma (KS) presenting as a protein-losing gastroenteropathy is a rare occurrence. We report the case of a 23-year-old male presenting with leg bilateral swelling and epigastric discomfort. A workup revealed human immunodeficiency virus seropositivity, hypoalbuminemia, and small bowel wall thickening on computed tomography scan. Initially there were no mucosal or cutaneous lesions visible. An upper endoscopy demonstrated subepithelial lesions with a reddish appearance involving the palate, cardia, duodenum, and jejunum, consistent with KS. Gastrointestinal involvement is the most common extracutaneous site of KS and is found in about half of the acquired immune deficiency syndrome (AIDS)-related cases. However, only one out of 5 patients are symptomatic in the absence of skin lesions. Antiretroviral therapy along with anthracycline chemotherapy must be promptly initiated to improve chances of survival.<\/jats:p>","DOI":"10.14309\/crj.0000000000000073","type":"journal-article","created":{"date-parts":[[2019,5,14]],"date-time":"2019-05-14T17:52:10Z","timestamp":1557856330000},"page":"e00073","source":"Crossref","is-referenced-by-count":2,"title":["Protein-Losing Enteropathy as the Initial Presentation of Gastrointestinal Kaposi's Sarcoma in Previously Undiagnosed HIV Disease"],"prefix":"10.14309","volume":"6","author":[{"given":"Diana","family":"Curras-Martin","sequence":"first","affiliation":[{"name":"Department of Medicine, Jersey Shore University Medical Center, Hackensack Meridian Health, Neptune, NJ"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natasha","family":"Campbell","sequence":"additional","affiliation":[{"name":"Department of Medicine, Jersey Shore University Medical Center, Hackensack Meridian Health, Neptune, NJ"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albino","family":"Copca-Alvarez","sequence":"additional","affiliation":[{"name":"Department of Medicine, Jersey Shore University Medical Center, Hackensack Meridian Health, Neptune, NJ"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen","family":"Casey","sequence":"additional","affiliation":[{"name":"Department of Medicine, Jersey Shore University Medical Center, Hackensack Meridian Health, Neptune, NJ"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William A.","family":"Lerner","sequence":"additional","affiliation":[{"name":"Department of Medicine, Jersey Shore University Medical Center, Hackensack Meridian Health, Neptune, NJ"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad A.","family":"Hossain","sequence":"additional","affiliation":[{"name":"Department of Medicine, Jersey Shore University Medical Center, Hackensack Meridian Health, Neptune, NJ"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2019,5,15]]},"reference":[{"issue":"4","key":"R1-20230717","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.clindermatol.2013.01.008","article-title":"Kaposi's sarcoma: Etiology and pathogenesis, inducing factors, causal associations, and treatments: Facts and controversies","volume":"31","author":"Ruocco","year":"2013","journal-title":"Clin Dermatol"},{"issue":"10","key":"R2-20230717","first-page":"838","article-title":"Protein-losing enteropathy syndrome caused by a localization of Kaposi's sarcoma in AIDS","volume":"13","author":"Bouhnik","year":"1989","journal-title":"Gastroenterol Clin Biol"},{"issue":"2","key":"R3-20230717","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1002\/path.4441","article-title":"The role of Kaposi sarcoma-associated herpesvirus in the pathogenesis of Kaposi 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