{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T15:57:43Z","timestamp":1786550263102,"version":"build-2736575974"},"reference-count":14,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:title>\n                    <jats:bold>ABSTRACT<\/jats:bold>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title\/>\n                    <jats:p>Achalasia is a disorder of the esophagus characterized by decreased lower esophageal sphincter (LES) relaxation and absence of esophageal peristalsis. Botulinum toxin (BT) injection targeting the LES has been used in the treatment of achalasia and other esophageal motility disorders, and it is considered to be safe and effective for short-term symptomatic relief. Serious adverse events of this procedure are rare. We report the case of an 83-year-old woman treated with BT injection for achalasia who subsequently developed a subdiaphragmatic abscess.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.14309\/crj.2017.119","type":"journal-article","created":{"date-parts":[[2017,12,1]],"date-time":"2017-12-01T16:44:21Z","timestamp":1512146661000},"page":"e119","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["A Case of Sub-Diaphragmatic Abscess after Injection of Botulinum Toxin to Treat Achalasia"],"prefix":"10.14309","volume":"4","author":[{"given":"Constantine","family":"Fisher","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frances","family":"Puello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samson","family":"Ferm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moshe","family":"Rubin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan H.","family":"Schnall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-119-20260710","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1053\/j.gastro.2012.12.027","article-title":"Outcomes of treatment for achalasia depend on manometric subtype.","volume":"144","author":"Rohof","year":"2013","journal-title":"Gastroenterol"},{"key":"R2-119-20260710","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1159\/000452354","article-title":"Diagnosis and treatment strategy of achalasia subtypes and esophagogastric junction outflow obstruction based on high resolution manometry.","volume":"95","author":"Ihara","year":"2017","journal-title":"Digestion"},{"issue":"12","key":"R3-119-20260710","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1055\/s-2001-18935","article-title":"Treatment of achalasia: Botulinum toxin injection vs. pneumatic balloon dilation. A prospective study with long-term follow-up.","volume":"33","author":"Allescher","year":"2001","journal-title":"Endoscopy"},{"issue":"12","key":"R4-119-20260710","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1056\/NEJM199503233321203","article-title":"Intrasphincteric botulinum toxin for the treatment of achalasia.","volume":"332","author":"Pasricha","year":"1995","journal-title":"N Engl J Med"},{"issue":"6","key":"R5-119-20260710","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1111\/j.1365-2036.2006.03079.x","article-title":"Review article: The management of achalasia: A comparison of different treatment modalities.","volume":"24","author":"Lake","year":"2006","journal-title":"Aliment Pharmacol Ther"},{"issue":"10","key":"R6-119-20260710","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1038\/ncpgasthep0951","article-title":"A case of mediastinitis following botulinum toxin type a treatment for achalasia.","volume":"4","author":"MacIver","year":"2007","journal-title":"Nat Clin Pract Gastroenterol Hepatol"},{"issue":"5","key":"R7-119-20260710","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1111\/den.12392","article-title":"Esophageal perforation, inflammatory mediastinitis and pseudoaneurysm of the thoracic aorta as potential complications of botulinum toxin injection for achalasia.","volume":"27","author":"Chao","year":"2015","journal-title":"Dig Endosc"},{"issue":"1","key":"R8-119-20260710","first-page":"38","article-title":"Clinical quiz. Sinus tract between esophagus and fundus.","volume":"35","author":"Fitzgerald","year":"2002","journal-title":"J Pediatr Gastroenterol Nutr"},{"issue":"9","key":"R9-119-20260710","first-page":"1724","article-title":"Symptomatic improvement in achalasia after botulinum toxin injection of the lower esophageal sphincter.","volume":"91","author":"Fishman","year":"1996","journal-title":"Am J Gastroenterol"},{"issue":"4","key":"R10-119-20260710","first-page":"283","article-title":"Botulinum toxin and gastrointestinal tract disorders. Panacea, placebo or pathway to the future?.","volume":"4","author":"Lacy","year":"2008","journal-title":"Gastroenterol Hepatol (N Y)"},{"issue":"1","key":"R11-119-20260710","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/S0016-5107(97)70306-7","article-title":"Treatment of achalasia by injection of botulinum toxin under endoscopic ultrasound guidance.","volume":"45","author":"Hoffman","year":"1997","journal-title":"Gastrointest Endosc"},{"issue":"11","key":"R12-119-20260710","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1055\/s-2000-10294","article-title":"Manometrically-guided endoscopic injection of botulinum toxin for esophageal achalasia: A pilot trial.","volume":"38","author":"Wehrmann","year":"2000","journal-title":"Z Gastroenterol"},{"issue":"3","key":"R13-119-20260710","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1097\/00004836-199504000-00004","article-title":"Endoscopic intrasphincteric injection of botulinum toxin for the treatment of achalasia.","volume":"20","author":"Rollan","year":"1995","journal-title":"J Clin Gastroenterol"},{"issue":"3","key":"R14-119-20260710","first-page":"1","article-title":"Complications of botulinum toxin injections for treatment of esophageal motility disorders.","volume":"30","author":"van Hoeij","year":"2017","journal-title":"Dis Esophagus"}],"container-title":["ACG Case Reports Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/02075970-201704000-00119","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T15:20:44Z","timestamp":1786548044000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/02075970-201704000-00119"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017]]}},"URL":"https:\/\/doi.org\/10.14309\/crj.2017.119","relation":{},"ISSN":["2326-3253"],"issn-type":[{"value":"2326-3253","type":"print"}],"subject":[],"published":{"date-parts":[[2017,1]]}}}