{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T13:21:10Z","timestamp":1790774470126,"version":"4.1.0"},"reference-count":19,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:title>\n                    <jats:bold>ABSTRACT<\/jats:bold>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title\/>\n                    <jats:p>Histoplasmosis is the most common endemic mycosis in the United States. Symptomatic gastrointestinal histoplasmosis is a rare entity. We report a case of isolated intestinal histoplasmosis that manifested as severe lower gastrointestinal bleeding in a renal transplant patient. The patient developed hematochezia, and colonoscopy showed diffuse, extensive areas of cratered, ulcerated mucosa in the entire colon. Biopsy showed prominent mucosal and submucosal infiltrate of plump histiocytes containing intracytoplasmic yeast forms morphologically compatible with florid histoplasmosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.14309\/crj.2017.93","type":"journal-article","created":{"date-parts":[[2017,8,3]],"date-time":"2017-08-03T15:50:43Z","timestamp":1501775443000},"page":"e93","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":8,"title":["Lower Gastrointestinal Bleeding Secondary to Intestinal Histoplasmosis in a Renal Transplant Patient"],"prefix":"10.14309","volume":"4","author":[{"given":"Taseen A.","family":"Syed","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Salem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald J.","family":"Kastens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"issue":"6","key":"R1-93-20260710","doi-asserted-by":"crossref","first-page":"e59","DOI":"10.1016\/j.mayocp.2014.10.022","article-title":"44-Year-old man with abdominal pain, fever, and bloody diarrhea.","volume":"90","author":"Bates","year":"2015","journal-title":"Mayo Clinic Proceedings"},{"issue":"2","key":"R2-93-20260710","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.ajg.2015.01.002","article-title":"Disseminated histoplasmosis mimicking metastatic disease of the colon and omentum: Report of a case and literature review.","volume":"16","author":"Romano","year":"2015","journal-title":"Arab J Gastroenterol"},{"issue":"5","key":"R3-93-20260710","first-page":"521","article-title":"Intestinal histoplasmosis in an HIV positive patient.","volume":"67","author":"Trombetta","year":"2007","journal-title":"Medicina (B Aires)"},{"issue":"6","key":"R4-93-20260710","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1016\/j.gie.2011.07.058","article-title":"Lower GI bleeding from ileocolonic histoplasmosis.","volume":"74","author":"Patel","year":"2011","journal-title":"Gastrointest Endosc"},{"issue":"1","key":"R5-93-20260710","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1053\/adpa.2003.50002","article-title":"Colonic histoplasmosis in acquired immunodeficiency syndrome mimicking carcinoma.","volume":"7","author":"Garcia","year":"2003","journal-title":"Ann Diagn Pathol"},{"issue":"6","key":"R6-93-20260710","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1016\/0002-9343(86)90390-6","article-title":"Histoplasmosis in patients with the acquired immune deficiency syndrome.","volume":"81","author":"Mandell","year":"1986","journal-title":"Am J Med"},{"issue":"4","key":"R7-93-20260710","first-page":"276","article-title":"Disseminated histoplasmosis presenting with ileal perforation in a renal transplant recipient.","volume":"95","author":"Zainudin","year":"1992","journal-title":"J Trop Med Hyg"},{"issue":"4","key":"R8-93-20260710","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1001\/archsurg.1993.01420160106018","article-title":"Intestinal perforation from gastrointestinal histoplasmosis in acquired immunodeficiency syndrome: Case report and review of the literature.","volume":"128","author":"Heneghan","year":"1993","journal-title":"Arch Surg"},{"issue":"1","key":"R9-93-20260710","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1001\/jama.1966.03100010100033","article-title":"Gastric histoplasmosis. A case report.","volume":"195","author":"Nudelman","year":"1966","journal-title":"JAMA"},{"issue":"3","key":"R10-93-20260710","first-page":"221","article-title":"Gastric histoplasmosis simulating a malignant gastric ulcer.","volume":"23","author":"Soto Tarazona","year":"2003","journal-title":"Rev Gastroenterol Peru"},{"issue":"1","key":"R11-93-20260710","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/S1473-3099(05)70328-5","article-title":"Gastric histoplasmosis.","volume":"6","author":"Hindupur","year":"2006","journal-title":"Lancet Infect Dis"},{"issue":"3","key":"R12-93-20260710","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1002\/ajh.2830470315","article-title":"Gastrointestinal histoplasmosis presenting as hematochezia in human immunodeficiency virus-infected hemophilic patients.","volume":"47","author":"Becherer","year":"1994","journal-title":"Am J Hematol"},{"issue":"1","key":"R13-93-20260710","first-page":"31","article-title":"Gastrointestinal histoplasmosis: An atypical presentation.","volume":"43","author":"Barros","year":"2013","journal-title":"Acta Gastroenterol Latinoam"},{"issue":"9","key":"R14-93-20260710","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1136\/jcp.41.9.992","article-title":"Caecal perforation in a renal transplant patient with disseminated histoplasmosis.","volume":"41","author":"Brett","year":"1988","journal-title":"J Clin Pathol"},{"issue":"3","key":"R15-93-20260710","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1086\/318485","article-title":"Gastrointestinal histoplasmosis in patients with AIDS: Case report and review.","volume":"32","author":"Suh","year":"2001","journal-title":"Clin Infect Dis"},{"issue":"1","key":"R16-93-20260710","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1111\/j.1572-0241.2005.40823.x","article-title":"Gastrointestinal histoplasmosis.","volume":"100","author":"Kahi","year":"2005","journal-title":"Am J Gastroenterol"},{"issue":"3","key":"R17-93-20260710","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1007\/BF01535762","article-title":"Gastrointestinal histoplasmosis.","volume":"33","author":"Cappell","year":"1988","journal-title":"Dig Dis Sci"},{"issue":"1","key":"R18-93-20260710","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1309\/X0Y2-P3GY-TWE8-DM02","article-title":"The pathologic spectrum of gastrointestinal and hepatic histoplasmosis.","volume":"113","author":"Lamps","year":"2000","journal-title":"Am J Clin Pathol"},{"issue":"5-6","key":"R19-93-20260710","first-page":"5336","article-title":"Cecal perforation in a kidney transplant patient: Disseminated histoplasmosis.","volume":"70","author":"Kourda","year":"2010","journal-title":"Med Trop (Mars)"}],"container-title":["ACG Case Reports Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/02075970-201704000-00093","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T15:18:51Z","timestamp":1786547931000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/02075970-201704000-00093"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1]]},"references-count":19,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017]]}},"URL":"https:\/\/doi.org\/10.14309\/crj.2017.93","relation":{},"ISSN":["2326-3253"],"issn-type":[{"value":"2326-3253","type":"print"}],"subject":[],"published":{"date-parts":[[2017,1]]}}}