{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T00:58:43Z","timestamp":1776387523632,"version":"3.51.2"},"reference-count":6,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2012,7,1]],"date-time":"2012-07-01T00:00:00Z","timestamp":1341100800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2012,7,1]],"date-time":"2012-07-01T00:00:00Z","timestamp":1341100800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Hormones"],"published-print":{"date-parts":[[2012,7]]},"DOI":"10.14310\/horm.2002.1368","type":"journal-article","created":{"date-parts":[[2014,1,31]],"date-time":"2014-01-31T19:07:11Z","timestamp":1391195231000},"page":"377-379","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["A novel finding in MNGIE (Mitochondrial Neurogastrointestinal Encephalomyopathy): hypergonadotropic hypogonadism"],"prefix":"10.1007","volume":"11","author":[{"given":"\u0130smail Hakk\u03b9","family":"Kalkan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00d6yk\u00fc","family":"Tayfur","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erkin","family":"\u00d6zta\u015f","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yavuz","family":"Beyazit","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hakan","family":"Yildiz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bilge","family":"Tun\u00e7","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2012,7,30]]},"reference":[{"key":"11030377_CR1","doi-asserted-by":"publisher","first-page":"1375","DOI":"10.1007\/s00431-010-1237-0","volume":"169","author":"Z Bari\u015f","year":"2010","unstructured":"Bari\u015f Z, Emino\u011flu T, Dalgi\u00e7 B, T\u00fcmer L, Hasano\u011flu A, 2010 Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE): case report with a new mutation. Eur J Pediatr 169: 1375\u20131378.","journal-title":"Eur J Pediatr"},{"key":"11030377_CR2","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1111\/j.1468-1331.2007.01720.x","volume":"14","author":"FJ Carod-Artal","year":"2007","unstructured":"Carod-Artal FJ, Herrero MD, Lara MC, et al, 2007 Cognitive dysfunction and hypogonadotrophic hypogonadism in a Brazilian patient with mitochondrial neurogastrointestinal encephalomyopathy and a novel ECGF1 mutation. Eur J Neurol 14: 581\u2013585.","journal-title":"Eur J Neurol"},{"key":"11030377_CR3","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1126\/science.283.5402.689","volume":"283","author":"I Nishino","year":"1999","unstructured":"Nishino I, Spinazzola A, Hirano M, 1999 Thymidine phosphorylase gene mutations in MNGIE, a human mitochondrial disorder. Science 283: 689\u2013692.","journal-title":"Science"},{"key":"11030377_CR4","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1507\/endocrj.44.805","volume":"44","author":"T Joko","year":"1997","unstructured":"Joko T, Iwashige K, Hashimoto T, et al, 1997 A case of mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes associated with diabetes mellitus and hypothalamo-pituitary dysfunction. Endocr J 44: 805\u2013809.","journal-title":"Endocr J"},{"key":"11030377_CR5","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1002\/(SICI)1098-1004(1997)10:3<212::AID-HUMU6>3.0.CO;2-K","volume":"10","author":"A Barrientos","year":"1997","unstructured":"Barrientos A, Casademont J, Genis D, et al, 1997 Sporadic heteroplasmic single 5.5 kb mitochondrial DNA deletion associated with cerebellar ataxia, hypogonadotropic hypogonadism, choroidal dystrophy, and mitochondrial respiratory chain complex I deficiency. Hum Mutat 10: 212\u2013216.","journal-title":"Hum Mutat"},{"key":"11030377_CR6","first-page":"396","volume":"70","author":"A Quade","year":"1992","unstructured":"Quade A, Zierz S, Klingm\u00fcller D, 1992 Endocrine abnormalities in mitochondrial myopathy with external ophthalmoplegia. Clin Investig 70: 396\u2013402.","journal-title":"Clin Investig"}],"container-title":["Hormones"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.14310\/horm.2002.1368.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.14310\/horm.2002.1368\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.14310\/horm.2002.1368.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,9]],"date-time":"2025-02-09T15:36:10Z","timestamp":1739115370000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.14310\/horm.2002.1368"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7]]},"references-count":6,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,7]]}},"alternative-id":["11030377"],"URL":"https:\/\/doi.org\/10.14310\/horm.2002.1368","relation":{},"ISSN":["1109-3099","2520-8721"],"issn-type":[{"value":"1109-3099","type":"print"},{"value":"2520-8721","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,7]]},"assertion":[{"value":"13 March 2012","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 June 2012","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 July 2012","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 July 2012","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}