{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T18:59:36Z","timestamp":1781031576432,"version":"3.54.1"},"reference-count":0,"publisher":"Aging and Disease","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["aging dis"],"abstract":"<jats:p>Neurological disorders affect more than three billion individuals worldwide. Conventional neurorehabilitation is constrained by therapist dependency, limited treatment intensity, poor patient adherence, and restricted accessibility. VR\/AR technologies offer immersive, high-dose, and remotely-deliverable alternatives to address these challenges. To synthesize current evidence on VR\/AR applications in major neurological disorders; to evaluate alignment with patient-centered care principals, to assess relevant technological aspects and clinical outcomes, and to identify economic considerations, research gaps, and future directions. A narrative review was conducted using searches from large databanks, encompassing clinical trials, systematic reviews, and meta-analyses of VR\/AR interventions in stroke, traumatic brain injury (TBI), spinal cord injury (SCI), Parkinson\u2019s diseases (PD), and multiple sclerosis (MS). Evidence was synthesized against a neurobiological and patient-centered care framework. VR and AR demonstrated clinically relevant potential across the neurological conditions examined. In stroke, VR added to conventional therapy produced moderate-certainty improvements in upper-limb motor recovery and balance. AR cueing significantly reduced freezing-of-gait duration and incidence in PD. VR interventions improved balance results in MS beyond those achieved with conventional therapy. In incomplete SCI, a large effect size on balance was reported, although with high heterogeneity. Some evidences support VR-based cognitive rehabilitation in TBI. Economic analysis indicated acceptable incremental cost-effectiveness and reimbursement pathways are emerging in several healthcare systems. VR\/AR technologies are promising patient-centered tools in neurorehabilitation. Key gaps including absence of standardized reporting protocols, insufficient large multicentre trials, long-term data lacking from low-resource-settings. Addressing these gaps is essential for equitable, evidence-based global implementation.<\/jats:p>","DOI":"10.14336\/ad.2026.0360","type":"journal-article","created":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T18:38:58Z","timestamp":1781030338000},"source":"Crossref","is-referenced-by-count":0,"title":["Immersive Technologies of Virtual and Augmented Reality (VR\/AR) in Patient-Centered Neurorehabilitation"],"prefix":"10.14336","member":"5462","published-online":{"date-parts":[[2026]]},"container-title":["aging and disease"],"original-title":[],"deposited":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T18:38:59Z","timestamp":1781030339000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.aginganddisease.org\/EN\/10.14336\/AD.2026.0360"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":0,"URL":"https:\/\/doi.org\/10.14336\/ad.2026.0360","relation":{},"ISSN":["2152-5250"],"issn-type":[{"value":"2152-5250","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}