{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T09:37:00Z","timestamp":1762421820396,"version":"build-2065373602"},"reference-count":21,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,12,30]],"date-time":"2023-12-30T00:00:00Z","timestamp":1703894400000},"content-version":"vor","delay-in-days":304,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Particle Therapy"],"published-print":{"date-parts":[[2023,3]]},"DOI":"10.14338\/ijpt-22-00032","type":"journal-article","created":{"date-parts":[[2023,2,16]],"date-time":"2023-02-16T10:26:05Z","timestamp":1676543165000},"page":"253-260","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Dosimetric Comparison of Intensity-Modulated Radiation Therapy (IMRT) and Intensity-Modulated Proton Therapy (IMPT) for a Novel Oral Tongue Avoidance Concept in Low-Risk Squamous Cell Carcinoma of the Oral Tongue"],"prefix":"10.1016","volume":"9","author":[{"given":"Robert H","family":"Press","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheng","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaakir","family":"Hasan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. Isabelle","family":"Choi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"II","given":"Charles B.","family":"Simone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arpit M.","family":"Chhabra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daphna Y.","family":"Gelblum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafi","family":"Kabarriti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard L.","family":"Bakst","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jen R.","family":"Cracchiolo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sean M.","family":"McBride","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nancy Y.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"journal-title":"Cancer Stat Facts: Tongue Cancer","year":"2021","author":"National Cancer Institute Surveillance Epidemiology and End Results Program (SEER).","key":"10.14338\/IJPT-22-00032_bib1"},{"key":"10.14338\/IJPT-22-00032_bib2","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1056\/NEJMoa1506007","article-title":"Elective versus therapeutic neck dissection in node-negative oral cancer","volume":"373","author":"D'Cruz","year":"2015","journal-title":"N Engl J Med"},{"key":"10.14338\/IJPT-22-00032_bib3","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1002\/cncr.27872","article-title":"Long-term regional control and survival in patients with \u201clow-risk,\u201d early stage oral tongue cancer managed by partial glossectomy and neck dissection without postoperative radiation: the importance of tumor thickness","volume":"119","author":"Ganly","year":"2013","journal-title":"Cancer"},{"key":"10.14338\/IJPT-22-00032_bib4","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1002\/hed.20423","article-title":"Management of contralateral N0 neck in oral cavity squamous cell carcinoma","volume":"28","author":"Koo","year":"2006","journal-title":"Head Neck"},{"key":"10.14338\/IJPT-22-00032_bib5","doi-asserted-by":"crossref","first-page":"2024","DOI":"10.1002\/hed.26671","article-title":"Contralateral neck failure in oral tongue cancer: outcomes from two centers using predefined treatment criteria","volume":"43","author":"Udovicich","year":"2021","journal-title":"Head Neck"},{"key":"10.14338\/IJPT-22-00032_bib6","first-page":"272","article-title":"Development of late toxicities in patients with oral tongue cancer treated with surgical resection and adjuvant radiation therapy","volume":"6","author":"Sayan","year":"2016","journal-title":"Front Oncol"},{"key":"10.14338\/IJPT-22-00032_bib7","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1002\/hed.23729","article-title":"Influence of surgical margins on local recurrence in T1\/T2 oral squamous cell carcinoma","volume":"37","author":"Barry","year":"2015","journal-title":"Head Neck"},{"key":"10.14338\/IJPT-22-00032_bib8","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1016\/j.ijrobp.2018.12.009","article-title":"Perineural invasion and perineural tumor spread in head and neck cancer","volume":"103","author":"Bakst","year":"2019","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.14338\/IJPT-22-00032_bib9","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1002\/hed.25110","article-title":"Patterns of recurrence in oral tongue cancer with perineural invasion","volume":"40","author":"Cracchiolo","year":"2018","journal-title":"Head Neck"},{"key":"10.14338\/IJPT-22-00032_bib10","doi-asserted-by":"crossref","first-page":"2329","DOI":"10.1002\/hed.25163","article-title":"Role of adverse pathological features in surgically treated early oral cavity carcinomas with adequate margins and the development of a scoring system to predict local control","volume":"40","author":"Subramaniam","year":"2018","journal-title":"Head Neck"},{"key":"10.14338\/IJPT-22-00032_bib11","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1001\/jamaoto.2016.3795","article-title":"Association of lymphovascular space invasion with locoregional failure and survival in patients with node-negative oral tongue cancers","volume":"143","author":"Cassidy","year":"2017","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"key":"10.14338\/IJPT-22-00032_bib12","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1002\/hed.20091","article-title":"Postoperative irradiation for squamous cell carcinoma of the oral cavity: 35-year experience","volume":"26","author":"Hinerman","year":"2004","journal-title":"Head Neck"},{"key":"10.14338\/IJPT-22-00032_bib13","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/j.ijrobp.2019.11.021","article-title":"A phase 2 trial of alternative volumes of oropharyngeal irradiation for de-intensification (AVOID): omission of the resected primary tumor bed after transoral robotic surgery for human papilloma virus-related squamous cell carcinoma of the oropharynx","volume":"106","author":"Swisher-McClure","year":"2020","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.14338\/IJPT-22-00032_bib14","doi-asserted-by":"crossref","first-page":"e13","DOI":"10.1016\/j.ijrobp.2021.12.034","article-title":"A prospective study of mucosal sparing proton beam therapy in resected oropharyngeal cancer patients","volume":"112","author":"Patel","year":"2022","journal-title":"Int J Radiat Oncol"},{"key":"10.14338\/IJPT-22-00032_bib15","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.radonc.2013.10.010","article-title":"Delineation of the neck node levels for head and neck tumors: a 2013 update. DAHANCA, EORTC, HKNPCSG, NCIC CTG, NCRI, RTOG, TROG consensus guidelines","volume":"110","author":"Gr\u00e9goire","year":"2014","journal-title":"Radiother Oncol J Eur Soc Ther Radiol Oncol"},{"key":"10.14338\/IJPT-22-00032_bib16","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.radonc.2015.07.041","article-title":"CT-based delineation of organs at risk in the head and neck region: DAHANCA, EORTC, GORTEC, HKNPCSG, NCIC CTG, NCRI, NRG Oncology and TROG consensus guidelines","volume":"117","author":"Brouwer","year":"2015","journal-title":"Radiother Oncol J Eur Soc Ther Radiol Oncol"},{"key":"10.14338\/IJPT-22-00032_bib17","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1016\/j.ijrobp.2020.09.037","article-title":"Node out, about it? Consideration of adjuvant treatment of oral tongue cancer","volume":"112","author":"Hara","year":"2022","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.14338\/IJPT-22-00032_bib18","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.radonc.2011.12.027","article-title":"Dose-response analysis of acute oral mucositis and pharyngeal dysphagia in patients receiving induction chemotherapy followed by concomitant chemo-IMRT for head and neck cancer","volume":"103","author":"Bhide","year":"2012","journal-title":"Radiother Oncol J Eur Soc Ther Radiol Oncol"},{"key":"10.14338\/IJPT-22-00032_bib19","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.radonc.2020.03.010","article-title":"Comparative analysis of acute toxicities and patient reported outcomes between intensity-modulated proton therapy (IMPT) and volumetric modulated arc therapy (VMAT) for the treatment of oropharyngeal cancer","volume":"147","author":"Manzar","year":"2020","journal-title":"Radiother Oncol J Eur Soc Ther Radiol Oncol"},{"key":"10.14338\/IJPT-22-00032_bib20","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1016\/j.ijrobp.2016.02.044","article-title":"Intensity modulated proton therapy versus intensity modulated photon radiation therapy for oropharyngeal cancer: first comparative results of patient-reported outcomes","volume":"95","author":"Sio","year":"2016","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.14338\/IJPT-22-00032_bib21","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1001\/jamaoto.2017.0001","article-title":"Estimating survival after salvage surgery for recurrent oral cavity cancer","volume":"143","author":"Tam","year":"2017","journal-title":"JAMA Otolaryngol Head Neck Surg"}],"container-title":["International Journal of Particle Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2331518023002421?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2331518023002421?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/meridian.allenpress.com\/theijpt\/article-pdf\/9\/4\/253\/3216181\/i2331-5180-9-4-253.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/meridian.allenpress.com\/theijpt\/article-pdf\/9\/4\/253\/3216181\/i2331-5180-9-4-253.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T09:33:32Z","timestamp":1762421612000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2331518023002421"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3]]},"references-count":21,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,3]]}},"alternative-id":["S2331518023002421"],"URL":"https:\/\/doi.org\/10.14338\/ijpt-22-00032","relation":{},"ISSN":["2331-5180"],"issn-type":[{"type":"print","value":"2331-5180"}],"subject":[],"published":{"date-parts":[[2023,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dosimetric Comparison of Intensity-Modulated Radiation Therapy (IMRT) and Intensity-Modulated Proton Therapy (IMPT) for a Novel Oral Tongue Avoidance Concept in Low-Risk Squamous Cell Carcinoma of the Oral Tongue","name":"articletitle","label":"Article Title"},{"value":"International Journal of Particle Therapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.14338\/IJPT-22-00032","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2023 \u00a9 2023 THE AUTHORS. Published by Elsevier BV on behalf of the Particle Therapy Co-operative Group. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}