{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T05:54:29Z","timestamp":1779256469523,"version":"3.51.4"},"reference-count":15,"publisher":"Endocrinology Research Centre","issue":"4","license":[{"start":{"date-parts":[[2020,12,7]],"date-time":"2020-12-07T00:00:00Z","timestamp":1607299200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.probl-endojournals.ru\/jour\/about\/editorialPolicies#openAccessPolicy"}],"content-domain":{"domain":["www.probl-endojournals.ru"],"crossmark-restriction":true},"short-container-title":["Probl Endokrinol (Mosk)"],"abstract":"<jats:p><jats:bold>RATIONALE<\/jats:bold>: Continuous subcutaneous insulin infusion (CSII) is an effective method for optimizing glycemic control in children with type 1 diabetes mellitus (DM1). However, the use of CSII does not always result in adequate glycemic control. Telehealth can be applied as one of the methods to improve the effectiveness of treatment.<\/jats:p><jats:p><jats:bold>AIMS<\/jats:bold>: To evaluate the use of remote medical support of children and adolescents with DM1 and its influence on glycemic control, quality of life, and incidence of acute complications of DM1.<\/jats:p><jats:p><jats:bold>MATERIALS AND METHODS<\/jats:bold>: We conducted a 24-week multi-institutional prospective open-label controlled clinical trial. 180 children and adolescents were included in this study and divided into the following categories: 1) age 8\u201318 years; 2) DM1 at least 1 year; 3) pump insulin therapy Medtronic Paradigm (Medtronic MiniMed, USA) at least 6 months; 4) self-monitoring of glycemia at least 4 times a day and replacement of the insulin pump infusion system at least once every 3 days; 5) inadequate glycemic control of DM1: the level of glycated hemoglobin (HbA<jats:sub>1c<\/jats:sub>) 7.5% or higher. Patients were assigned to a remote consultation group (RC; n=100) or a traditional control group (TC; n=80). All patients were trained on the basic principles of DM1 and CSII, and we measured initial HbA<jats:sub>1c<\/jats:sub>, then after 12 and 24 weeks, also registered and analyzed glycemic indicators and daily doses of insulin, evaluated and corrected the treatment. Patients or their parents in the RC group sent pump data via the Internet to the pump insulin therapy center at least once every 2 weeks at home and received treatment recommendations in response.<\/jats:p><jats:p><jats:bold>RESULTS<\/jats:bold>: The total number of patients included in the study in all institutions was 180 children at 8\u201318 years. Patients in both groups did not differ in age, gender, duration of DM1 and CSII, and HbA<jats:sub>1c<\/jats:sub> level. The total amount of remote consultations for all institutions was 949. The decrease in the level of HbA<jats:sub>1c<\/jats:sub> by the end of the study against the initial one was statistically significantly greater in the RC group: 1.17% compared to 0.59% in the TC group (p&lt;0.05). The proportion of patients who reached the target level of HbA<jats:sub>1c<\/jats:sub> (&lt;7.5%) was significantly higher in the RC group (32%) compared to the TC group (12.5%, p&lt;0.05). During the study, the incidence of DKA and severe hypoglycemia in the RC group was statistically significantly lower.<\/jats:p><jats:p><jats:bold>CONCLUSIONS<\/jats:bold>: Remote monitoring in children with DM1 resulted in significant improvements in glycemic control (HbA<jats:sub>1c<\/jats:sub>, glycemic variability, and hypoglycemic frequency). The accumulation of evidence on the effectiveness and safety of telehealth in DM should contribute to implementing this approach in practical health care.<\/jats:p>","DOI":"10.14341\/probl12201","type":"journal-article","created":{"date-parts":[[2020,12,8]],"date-time":"2020-12-08T11:05:04Z","timestamp":1607425504000},"page":"50-60","update-policy":"https:\/\/doi.org\/10.14341\/crossmarkpolicy2018","source":"Crossref","is-referenced-by-count":8,"title":["Remote monitoring and treatment of children and adolescents with type 1 diabetes"],"prefix":"10.14341","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4316-8546","authenticated-orcid":true,"given":"Dmitry N.","family":"Laptev","sequence":"first","affiliation":[{"name":"Endocrinology Research Centre"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3742-0231","authenticated-orcid":true,"given":"Andrey O.","family":"Emelyanov","sequence":"additional","affiliation":[{"name":"Endocrinology Research Centre"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2667-4842","authenticated-orcid":true,"given":"Yulia G.","family":"Samoilova","sequence":"additional","affiliation":[{"name":"Siberian State Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8968-3925","authenticated-orcid":true,"given":"Elena B.","family":"Khramova","sequence":"additional","affiliation":[{"name":"Tyumenian State Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8520-2378","authenticated-orcid":true,"given":"Elena E.","family":"Petriaikina","sequence":"additional","affiliation":[{"name":"Morozov Children City Clinical Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irina G.","family":"Rybkina","sequence":"additional","affiliation":[{"name":"Morozov Children City Clinical Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alla Yu.","family":"Filimonova","sequence":"additional","affiliation":[{"name":"Regional Children Clinical Hospital named after N.V. Dmitrieva"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3742-0231","authenticated-orcid":true,"given":"Valentina A.","family":"Peterkova","sequence":"additional","affiliation":[{"name":"Endocrinology Research Centre"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5458","published-online":{"date-parts":[[2020,12,7]]},"reference":[{"key":"ref1","unstructured":"Dedov II, Peterkova VA, Kuraeva TL, et al. Pompovaya insulinoterapiya sakharnogo diabeta u detei i podrostkov. Rossiiskii konsensus detskikh endokrinologov. Problemy endokrinologii. 2012;58(2-2):2\u221218. (In Russ.)."},{"key":"ref2","unstructured":"Dedov II, Peterkova VA, Kuraeva TL, Laptev DN. Insulinovaya pompa (pomoshch\u2019 vrachu i patsientu dlya effektivnogo upravleniya diabetom). Moscow; 2014. 128 \u0440. (In Russ.)."},{"key":"ref3","doi-asserted-by":"crossref","unstructured":"Emel\u2019yanov AO, Kuraeva TL, Laptev DN, Peterkova VA. 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