{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T22:56:04Z","timestamp":1761519364038,"version":"3.37.3"},"reference-count":18,"publisher":"Endocrinology Research Centre","issue":"4","license":[{"start":{"date-parts":[[2022,6,6]],"date-time":"2022-06-06T00:00:00Z","timestamp":1654473600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.probl-endojournals.ru\/jour\/about\/editorialPolicies#openAccessPolicy"}],"content-domain":{"domain":["www.probl-endojournals.ru"],"crossmark-restriction":true},"short-container-title":["Probl Endokrinol (Mosk)"],"abstract":"<jats:p>Presented case demonstrates a rare diencephalic pathology \u2014 adipsic diabetes insipidus (ADI) with severe hypernatremia in a 58-year-old woman after ttranssphenoidal removal of stalk intraventricular craniopharyngioma. ADI was diagnosed because of hypernatremia (150\u2013155 mmol\/L), polyuria (up to 4 liters per day) and absence of thirst. Normalization of water-electrolyte balance occurred on the background of desmopressin therapy and sufficient hydration in postoperative period. After release from the hospital, the patient independently stopped desmopressin therapy and did not consume an adequate amount of fluid of the background of polyuria. This led to severe hypernatremia (155\u2013160 mmol\/L) and rough mental disorders.<\/jats:p><jats:p>Patients with ADI need closely monitoring of medical condition and water-electrolyte parameters, appointment of fixed doses of desmopressin and adequate hydration.<\/jats:p>","DOI":"10.14341\/probl13126","type":"journal-article","created":{"date-parts":[[2022,9,15]],"date-time":"2022-09-15T05:34:44Z","timestamp":1663220084000},"page":"40-45","update-policy":"https:\/\/doi.org\/10.14341\/crossmarkpolicy2018","source":"Crossref","is-referenced-by-count":2,"title":["Adipsic diabetes insipidus after transsphenoidal surgery for suprasellar intraventricular"],"prefix":"10.14341","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4480-1902","authenticated-orcid":true,"given":"L.\u200a I.","family":"Astafyeva","sequence":"first","affiliation":[{"name":"Burdenko Neurosurgery Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2211-4298","authenticated-orcid":true,"given":"I. N.","family":"Badmaeva","sequence":"additional","affiliation":[{"name":"Burdenko Neurosurgery Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2733-5874","authenticated-orcid":true,"given":"Yu. G.","family":"Sidneva","sequence":"additional","affiliation":[{"name":"Burdenko Neurosurgery Center; Clinical and Research Institute of Emergency Pediatric Surgery and Trauma (CRIEPST)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7440-4687","authenticated-orcid":true,"given":"I. S.","family":"Klochkova","sequence":"additional","affiliation":[{"name":"Burdenko Neurosurgery Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5323-1000","authenticated-orcid":true,"given":"D. V.","family":"Fomichev","sequence":"additional","affiliation":[{"name":"Burdenko Neurosurgery Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9789-3452","authenticated-orcid":true,"given":"I. V.","family":"Chernov","sequence":"additional","affiliation":[{"name":"Burdenko Neurosurgery Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9333-9473","authenticated-orcid":true,"given":"P. L.","family":"Kalinin","sequence":"additional","affiliation":[{"name":"Burdenko Neurosurgery Center"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5458","published-online":{"date-parts":[[2022,6,6]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","unstructured":"Erfurth EM. Diagnosis, Background, and Treatment of Hypothalamic Damage in Craniopharyngioma. 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Clinical Endocrinology. 2004;61(2):273-279. doi: https:\/\/doi.org\/10.1111\/j.1365-2265.2004.02086.x","DOI":"10.1111\/j.1365-2265.2004.02086.x"},{"key":"ref5","doi-asserted-by":"crossref","unstructured":"Olsson DS, Andersson E, Bryngelsson I-L, et al. Excess Mortality and Morbidity in Patients with Craniopharyngioma, Especially in Patients with Childhood Onset: A Population-Based Study in Sweden. J Clin Endocrinol Metab. 2015;100(2):467-474. doi: https:\/\/doi.org\/10.1210\/jc.2014-3525","DOI":"10.1210\/jc.2014-3525"},{"key":"ref6","doi-asserted-by":"crossref","unstructured":"Hensen J, Henig A, Fahlbusch R, Meyer M, Boehnert M, Buchfelder M. Prevalence, predictors and patterns of postoperative polyuria and hyponatraemia in the immediate course after transsphenoidal surgery for pituitary adenomas. Clin Endocrinol (Oxf). 1999;50(4):431-439. doi: https:\/\/doi.org\/10.1046\/j.1365-2265.1999.00666.x","DOI":"10.1046\/j.1365-2265.1999.00666.x"},{"key":"ref7","doi-asserted-by":"crossref","unstructured":"Adams JR, Blevins LS, Allen GS, et al. Disorders of water metabolism following transsphenoidal pituitary surgery: A single institution\u2019s experience. Pituitary. 2006;9(2):93-99. doi: https:\/\/doi.org\/10.1007\/s11102-006-9276-2","DOI":"10.1007\/s11102-006-9276-2"},{"key":"ref8","doi-asserted-by":"crossref","unstructured":"Nemergut EC, Zuo Z, Jane JA, Laws ER. Predictors of diabetes insipidus after transsphenoidal surgery: a review of 881 patients. J Neurosurg. 2005;103(3):448-454. doi: https:\/\/doi.org\/10.3171\/jns.2005.103.3.0448","DOI":"10.3171\/jns.2005.103.3.0448"},{"key":"ref9","doi-asserted-by":"crossref","unstructured":"Schreckinger M, Walker B, Knepper J, et al. Postoperative diabetes insipidus after endoscopic transsphenoidal surgery. Pituitary. 2013;16(4):445-451. doi: https:\/\/doi.org\/10.1007\/s11102-012-0453-1","DOI":"10.1007\/s11102-012-0453-1"},{"key":"ref10","doi-asserted-by":"crossref","unstructured":"Eisenberg Y, Frohman LA. Adipsic diabetes insipidus: A review. Endocrine Practice. 2016;22(1):76-83. doi: https:\/\/doi.org\/10.4158\/EP15940.RA","DOI":"10.4158\/EP15940.RA"},{"key":"ref11","doi-asserted-by":"crossref","unstructured":"Robertson GL. Abnormalities of thirst regulation. Kidney Int. 1984;25(2):460-469. doi: https:\/\/doi.org\/10.1038\/ki.1984.39","DOI":"10.1038\/ki.1984.39"},{"key":"ref12","doi-asserted-by":"crossref","unstructured":"Arima H, Wakabayashi T, Nagatani T, et al. Adipsia increases risk of death in patients with central diabetes insipidus. Endocr J. 2014;61(2):143-148. doi: https:\/\/doi.org\/10.1507\/endocrj.EJ13-0368","DOI":"10.1507\/endocrj.EJ13-0368"},{"key":"ref13","doi-asserted-by":"crossref","unstructured":"Crowley RK, Sherlock M, Agha A, et al. Clinical insights into adipsic diabetes insipidus: a large case series. Clin Endocrinol (Oxf). 2007;47(4):475-482. doi: https:\/\/doi.org\/10.1111\/j.1365-2265.2007.02754.x","DOI":"10.1111\/j.1365-2265.2007.02754.x"},{"key":"ref14","doi-asserted-by":"crossref","unstructured":"Cuesta M, Hannon MJ, Thompson CJ. Adipsic diabetes insipidus in adult patients. Pituitary. 2017;20(3):372-380. doi: https:\/\/doi.org\/10.1007\/s11102-016-0784-4","DOI":"10.1007\/s11102-016-0784-4"},{"key":"ref15","doi-asserted-by":"crossref","unstructured":"Ball SG, Vaidja B, Baylis PH. Hypothalamic adipsic syndrome: diagnosis and management. Clin Endocrinol (Oxf). 1997;47(4):405-409. doi: https:\/\/doi.org\/10.1046\/j.1365-2265.1997.2591079.x","DOI":"10.1046\/j.1365-2265.1997.2591079.x"},{"key":"ref16","doi-asserted-by":"crossref","unstructured":"Pigarova EA, Dzeranova LK. Diagnosis and treatment of central diabetes insipidus. Obesity and metabolism. 2014;11(4):48-55. 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