{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T21:31:53Z","timestamp":1740173513289,"version":"3.37.3"},"reference-count":16,"publisher":"Endocrinology Research Centre","issue":"5","license":[{"start":{"date-parts":[[2023,11,11]],"date-time":"2023-11-11T00:00:00Z","timestamp":1699660800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.probl-endojournals.ru\/jour\/about\/editorialPolicies#openAccessPolicy"}],"content-domain":{"domain":["www.probl-endojournals.ru"],"crossmark-restriction":true},"short-container-title":["Probl Endokrinol (Mosk)"],"abstract":"<jats:p>Reset osmostat syndrome (ROS) is characterized by a change of normal plasma osmolality threshold (decrease or increase), which leads to chronic dysnatremia (hypo- or hypernatremia). We have described a clinical case of ROS and chronic hyponatremia in a patient with chordoid glioma of the III ventricle. It is known that the patient had previously been diagnosed with hyponatremia (131\u2013134 mmol\/l). She has not hypothyroidism and hypocorticism. There is normal filtration function of the kidneys was (CKD-EPI 91.7 ml\/mi\/1,73m<jats:sup>2<\/jats:sup>). Urine osmolality and sodium level were studied to exclude of concentration kidney function disorder. During first three days after removal of the tumor of the third ventricle (chordoid glioma, WHO Grade II), the sodium level decreased to 119 mmol\/l. Repeated infusions of 200\u2013300 ml hypertonic 3% sodium chloride solution, gluco- and mineralocorticoid therapy was ineffective, increasing plasma sodium levels by 2\u20133 mmol\/l with the return to the initial level during 6\u20138 hours. Hypopituitary disorders did not develop after surgery. With further observation, the sodium level remained within 126\u2013129 mmol\/l for 6 months after surgery. The water load test make exclude the classic syndrome of inappropriate secretion of antidiuretic hormone, and confirmed the diagnosis of RSO. Because of absence of clinical symptoms associated with hyponatremia, no medical correction was required, patient was recommended to clinical follow-up.<\/jats:p>","DOI":"10.14341\/probl13235","type":"journal-article","created":{"date-parts":[[2023,11,14]],"date-time":"2023-11-14T09:56:36Z","timestamp":1699955796000},"page":"65-72","update-policy":"https:\/\/doi.org\/10.14341\/crossmarkpolicy2018","source":"Crossref","is-referenced-by-count":0,"title":["Reset osmostat syndrome \u2014 when hyponatremia become \u00aba normal\u00bb: diagnostics, case report"],"prefix":"10.14341","volume":"69","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4480-1902","authenticated-orcid":true,"given":"L. I.","family":"Astafyeva","sequence":"first","affiliation":[{"name":"Burdenko Neurosurgery Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2211-4298","authenticated-orcid":true,"given":"I. N.","family":"Badmaeva","sequence":"additional","affiliation":[{"name":"Burdenko Neurosurgery Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7440-4687","authenticated-orcid":true,"given":"I. S.","family":"Klochkova","sequence":"additional","affiliation":[{"name":"Burdenko Neurosurgery Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2733-5874","authenticated-orcid":true,"given":"Yu. G.","family":"Sidneva","sequence":"additional","affiliation":[{"name":"Burdenko Neurosurgery Center; Clinical and Research Institute of Emergency Pediatric Surgery and Trauma"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3777-5662","authenticated-orcid":true,"given":"O. I.","family":"Sharipov","sequence":"additional","affiliation":[{"name":"Burdenko Neurosurgery Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O. A.","family":"Gadjieva","sequence":"additional","affiliation":[{"name":"Burdenko Neurosurgery Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5559-2678","authenticated-orcid":true,"given":"B. A.","family":"Bashiryan","sequence":"additional","affiliation":[{"name":"Burdenko Neurosurgery Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9333-9473","authenticated-orcid":true,"given":"P. L.","family":"Kalinin","sequence":"additional","affiliation":[{"name":"Burdenko Neurosurgery Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2595-5877","authenticated-orcid":true,"given":"A. Yu.","family":"Lubnin","sequence":"additional","affiliation":[{"name":"Burdenko Neurosurgery Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. N.","family":"Konovalov","sequence":"additional","affiliation":[{"name":"Burdenko Neurosurgery Center"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5458","published-online":{"date-parts":[[2023,11,11]]},"reference":[{"key":"ref1","unstructured":"Peng Goh K. Water and sodium balance management of hyponatremia. Am Fam Physician. 2004;69(10):2387-2394."},{"key":"ref2","doi-asserted-by":"crossref","unstructured":"Milionis HJ, Liamis GL, Elisaf MS. The hyponatremic patient: A systematic approach to laboratory diagnosis. 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(In Russ.)."}],"container-title":["Problems of Endocrinology"],"original-title":[],"link":[{"URL":"https:\/\/www.probl-endojournals.ru\/jour\/article\/viewFile\/13235\/10537","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,11,14]],"date-time":"2023-11-14T09:57:07Z","timestamp":1699955827000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.probl-endojournals.ru\/jour\/article\/view\/13235"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,11]]},"references-count":16,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2023,11,12]]}},"URL":"https:\/\/doi.org\/10.14341\/probl13235","relation":{},"ISSN":["2308-1430","0375-9660"],"issn-type":[{"type":"electronic","value":"2308-1430"},{"type":"print","value":"0375-9660"}],"subject":[],"published":{"date-parts":[[2023,11,11]]}}}