{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T16:08:15Z","timestamp":1789056495744,"version":"build-2803163510"},"reference-count":22,"publisher":"Endocrinology Research Centre","issue":"4","license":[{"start":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T00:00:00Z","timestamp":1788825600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.probl-endojournals.ru\/jour\/about\/editorialPolicies#openAccessPolicy"}],"content-domain":{"domain":["www.probl-endojournals.ru"],"crossmark-restriction":true},"short-container-title":["Probl Endokrinol (Mosk)"],"abstract":"<jats:p>Thyrotoxic crisis (TC) is a rare but potentially life-threatening complication of decompensated thyrotoxicosis that requires immediate medical intervention. The diagnosis of TC is based on a clinical picture of severe hyperthyroidism in combination with precipitating factors. Treatment should be initiated at the first suspicion of crisis development, without waiting for the results of hormonal analysis, which may take considerable time to obtain. This article presents a clinical case of a female patient with coexisting Graves\u2019 disease and type 1 diabetes mellitus, in whom TC was promptly recognized and effectively managed. The precipitating factor was diabetic ketoacidosis. This case highlights the importance of early diagnosis and intensive therapy to improve the prognosis of patients with TC.<\/jats:p>","DOI":"10.14341\/probl13688","type":"journal-article","created":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T15:36:30Z","timestamp":1789054590000},"page":"46-52","update-policy":"https:\/\/doi.org\/10.14341\/crossmarkpolicy2018","source":"Crossref","is-referenced-by-count":0,"title":["Thyrotoxic crisis in a patient with coexisting Graves\u2019 disease and type 1 diabetes mellitus"],"prefix":"10.14341","volume":"72","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0560-8843","authenticated-orcid":true,"given":"L. I.","family":"Danilova","sequence":"first","affiliation":[{"name":"Belarusian State Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7679-0032","authenticated-orcid":true,"given":"G. G.","family":"Korolenko","sequence":"additional","affiliation":[{"name":"Belarusian State Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5258-9182","authenticated-orcid":true,"given":"M. L.","family":"Lushchyk","sequence":"additional","affiliation":[{"name":"Belarusian State Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-4538-5780","authenticated-orcid":true,"given":"O. V.","family":"Chaplinskaya","sequence":"additional","affiliation":[{"name":"Gomel City Clinical Hospital \u21163"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-5063-3786","authenticated-orcid":true,"given":"I. I.","family":"Bourko","sequence":"additional","affiliation":[{"name":"Belarusian State Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5458","published-online":{"date-parts":[[2026,9,8]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","unstructured":"Ross DS, Burch HB, Cooper DS, et al. American Thyroid Association Guidelines for Diagnosis and Management of Hyperthyroidism and Other Causes of Thyrotoxicosis. Thyroid. 2016;26(10):1343\u20131421. doi: https:\/\/doi.org\/10.1089\/thy.2016.0229","DOI":"10.1089\/thy.2016.0229"},{"key":"ref2","doi-asserted-by":"crossref","unstructured":"Galindo RJ, Hurtado CR, Pasquel FJ, et al. National Trends in Incidence, Mortality, and Clinical Outcomes of Patients Hospitalized for Thyrotoxicosis With and Without Thyroid Storm in the United States, 2004\u20132013. 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