{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T13:06:36Z","timestamp":1775307996471,"version":"3.50.1"},"reference-count":0,"publisher":"Endocrinology Research Centre","issue":"2","license":[{"start":{"date-parts":[[2009,4,15]],"date-time":"2009-04-15T00:00:00Z","timestamp":1239753600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["probl-endojournals.ru"],"crossmark-restriction":false},"short-container-title":["Probl Endokrinol (Mosk)"],"abstract":"<jats:p>Thyrotoxicosis of newborns, observed in less than 1% of pregnant women with Graves disease, is due to transplacental transfer of stimulating antibodies to the thyroid stimulating hormone receptor (rTSH). The clinical picture manifests itself in the first days of a child\u2019s life, is transient in nature and, as a rule, ends with a full recovery as the maternal antibodies to rTSH disappear from the bloodstream of the newborn. However, in addition to the \"classic\" autoimmune thyrotoxicosis, cases of congenital and familial non-autoimmune thyrotoxicosis, which are caused by inherited activating mutations of the gene encoding rTSH - TSHR, have been described. This article presents its own observation.<\/jats:p>","DOI":"10.14341\/probl200955248-50","type":"journal-article","created":{"date-parts":[[2014,3,22]],"date-time":"2014-03-22T11:00:24Z","timestamp":1395486024000},"page":"48-50","update-policy":"https:\/\/doi.org\/10.14341\/crossmarkpolicy2018","source":"Crossref","is-referenced-by-count":1,"title":["Non-immune thyrotoxicosis caused by thyroid-stimulating hormone receptor activating gene mutation (the first description in Russia)"],"prefix":"10.14341","volume":"55","author":[{"given":"V A","family":"Peterkova","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O V","family":"Vasyukova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A N","family":"Tyul'pakov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5458","published-online":{"date-parts":[[2009,4,15]]},"container-title":["Problems of Endocrinology"],"original-title":[],"link":[{"URL":"https:\/\/probl-endojournals.ru\/probl\/article\/viewFile\/11106\/8020","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/probl-endojournals.ru\/probl\/article\/viewFile\/11106\/8020","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,30]],"date-time":"2019-09-30T11:45:22Z","timestamp":1569843922000},"score":1,"resource":{"primary":{"URL":"https:\/\/probl-endojournals.ru\/probl\/article\/view\/11106"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,4,15]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2009,4,15]]}},"URL":"https:\/\/doi.org\/10.14341\/probl200955248-50","relation":{},"ISSN":["2308-1430","0375-9660"],"issn-type":[{"value":"2308-1430","type":"electronic"},{"value":"0375-9660","type":"print"}],"subject":[],"published":{"date-parts":[[2009,4,15]]}}}