{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,3]],"date-time":"2022-04-03T15:43:00Z","timestamp":1649000580441},"reference-count":0,"publisher":"Endocrinology Research Centre","issue":"5","license":[{"start":{"date-parts":[[2009,10,15]],"date-time":"2009-10-15T00:00:00Z","timestamp":1255564800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["probl-endojournals.ru"],"crossmark-restriction":false},"short-container-title":["Probl Endokrinol (Mosk)"],"abstract":"<jats:p>The objective of this study was to study dynamics of prevalence of functional thyroid dysfunctions among pregnant women. The levels of TSH, free T4, and antithyroid peroxidase antibodies (ATP-AB) were measured in randomly selected women of different gestational age who applied to be registered in a maternity welfare centre in 1999-2003 (n = 215) and 2006-2008 (n = 325). The available data indicate that iodine consumption by the study populations increased during the above periods even if still remains subnormal. No statistically significant decrease in the occurrence of ATP-AB and hypothyroidism was recorded. Women carrying ATP-AB in the first and seconds trimesters of pregnancy had significantly higher TSH levels compared to those without ATP-AB. A change of diagnostic criteria for hypothyroidism (lowering the reference TSH threshold from 4.0 to 2.5 mU\/l accounts for a several-fold rise (by a factor of 2-7) in the prevalence of hypothyroidism among pregnant women.<\/jats:p>","DOI":"10.14341\/probl200955514-19","type":"journal-article","created":{"date-parts":[[2014,3,22]],"date-time":"2014-03-22T06:58:59Z","timestamp":1395471539000},"page":"14-19","update-policy":"http:\/\/dx.doi.org\/10.14341\/crossmarkpolicy2018","source":"Crossref","is-referenced-by-count":0,"title":["Dynamics of prevalence of functional thyroid dysfunctions among pregnant women in Moscow from 1999 to 2008"],"prefix":"10.14341","volume":"55","author":[{"given":"V V","family":"Fadeyev","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S P","family":"Topalyan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S V","family":"Lesnikova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G A","family":"Mel'nichenko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5458","published-online":{"date-parts":[[2009,10,15]]},"container-title":["Problems of Endocrinology"],"original-title":[],"link":[{"URL":"https:\/\/probl-endojournals.ru\/probl\/article\/viewFile\/11138\/8052","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/probl-endojournals.ru\/probl\/article\/viewFile\/11138\/8052","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,30]],"date-time":"2019-09-30T07:24:06Z","timestamp":1569828246000},"score":1,"resource":{"primary":{"URL":"https:\/\/probl-endojournals.ru\/probl\/article\/view\/11138"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,10,15]]},"references-count":0,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2009,10,15]]}},"URL":"https:\/\/doi.org\/10.14341\/probl200955514-19","relation":{},"ISSN":["2308-1430","0375-9660"],"issn-type":[{"value":"2308-1430","type":"electronic"},{"value":"0375-9660","type":"print"}],"subject":[],"published":{"date-parts":[[2009,10,15]]}}}