{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T02:15:18Z","timestamp":1769912118445,"version":"3.49.0"},"reference-count":51,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2017,4,1]],"date-time":"2017-04-01T00:00:00Z","timestamp":1491004800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,4,1]],"date-time":"2017-04-01T00:00:00Z","timestamp":1491004800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2017,3,21]],"date-time":"2017-03-21T00:00:00Z","timestamp":1490054400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/3.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecules and Cells"],"published-print":{"date-parts":[[2017,4]]},"DOI":"10.14348\/molcells.2017.2295","type":"journal-article","created":{"date-parts":[[2017,5,18]],"date-time":"2017-05-18T04:22:54Z","timestamp":1495081374000},"page":"262-270","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Identification and Expression of Equine MER-Derived miRNAs"],"prefix":"10.1016","volume":"40","author":[{"given":"Jeong-An","family":"Gim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heui-Soo","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.14348\/molcells.2017.2295_bib1","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/j.gene.2012.08.028","article-title":"The novel MER transposon-derived miRNAs in human genome","volume":"512","author":"Ahn","year":"2013","journal-title":"Gene"},{"key":"10.14348\/molcells.2017.2295_bib2","doi-asserted-by":"crossref","first-page":"2697","DOI":"10.1093\/nar\/gki567","article-title":"Clustering and conservation patterns of human microRNAs","volume":"33","author":"Altuvia","year":"2005","journal-title":"Nucleic Acids Res"},{"key":"10.14348\/molcells.2017.2295_bib3","doi-asserted-by":"crossref","first-page":"351","DOI":"10.3109\/08830185.2010.485333","article-title":"Implication of human endogenous retroviruses in the development of autoimmune diseases","volume":"29","author":"Balada","year":"2010","journal-title":"Int Rev Immunol"},{"key":"10.14348\/molcells.2017.2295_bib4","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.cell.2009.01.002","article-title":"MicroRNAs: target recognition and regulatory functions","volume":"136","author":"Bartel","year":"2009","journal-title":"Cell"},{"key":"10.14348\/molcells.2017.2295_bib5","doi-asserted-by":"crossref","first-page":"8","DOI":"10.4161\/mge.1.1.15766","article-title":"Comprehensive analysis of microRNA genomic loci identifies pervasive repetitive-element origins","volume":"1","author":"Borchert","year":"2011","journal-title":"Mob Genet Elements"},{"key":"10.14348\/molcells.2017.2295_bib6","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1038\/nrg1990","article-title":"The evolution of gene regulation by transcription factors and microRNAs","volume":"8","author":"Chen","year":"2007","journal-title":"Nat Rev Genet"},{"key":"10.14348\/molcells.2017.2295_bib7","first-page":"264","article-title":"Evolution of retroviruses: fossils in our DNA","volume":"148","author":"Coffin","year":"2004","journal-title":"Proc Am Philos Soc"},{"key":"10.14348\/molcells.2017.2295_bib8","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1101\/gr.128991.111","article-title":"Identification of copy number variants in horses","volume":"22","author":"Doan","year":"2012","journal-title":"Genome Res"},{"key":"10.14348\/molcells.2017.2295_bib9","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/j.modgep.2005.09.003","article-title":"Spatio-temporal patterns of intestine-specific transcription factor expression during postnatal mouse gut development","volume":"6","author":"Fang","year":"2006","journal-title":"Gene Expr Patterns"},{"key":"10.14348\/molcells.2017.2295_bib10","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1093\/genetics\/163.2.747","article-title":"Genome-wide analysis of mariner-like transposable elements in rice reveals complex relationships with stowaway miniature inverted repeat transposable elements (MITEs)","volume":"163","author":"Feschotte","year":"2003","journal-title":"Genetics"},{"key":"10.14348\/molcells.2017.2295_bib11","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1385\/MB:32:3:197","article-title":"A novel method to monitor the expression of microRNAs","volume":"32","author":"Fu","year":"2006","journal-title":"Mol Biotechnol"},{"key":"10.14348\/molcells.2017.2295_bib12","doi-asserted-by":"crossref","first-page":"261","DOI":"10.5808\/GI.2014.12.4.261","article-title":"Genome-wide identification and classification of microRNAs derived from repetitive elements","volume":"12","author":"Gim","year":"2014","journal-title":"Genomics Inform"},{"key":"10.14348\/molcells.2017.2295_bib13","doi-asserted-by":"crossref","first-page":"210","DOI":"10.14348\/molcells.2015.2138","article-title":"Genome-wide analysis of DNA methylation before-and after exercise in the thoroughbred horse with MeDIP-Seq","volume":"38","author":"Gim","year":"2015","journal-title":"Mol Cells"},{"key":"10.14348\/molcells.2017.2295_bib14","doi-asserted-by":"crossref","first-page":"9628","DOI":"10.1158\/0008-5472.CAN-05-2352","article-title":"A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation","volume":"65","author":"Hayashita","year":"2005","journal-title":"Cancer Res"},{"issue":"Suppl 2","key":"10.14348\/molcells.2017.2295_bib15","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1111\/j.1365-2052.2010.02104.x","article-title":"Targets of selection in the Thoroughbred genome contain exercise-relevant gene SNPs associated with elite racecourse performance","volume":"41","author":"Hill","year":"2010","journal-title":"Anim Genet"},{"key":"10.14348\/molcells.2017.2295_bib16","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1093\/nar\/30.1.38","article-title":"The Ensembl genome database project","volume":"30","author":"Hubbard","year":"2002","journal-title":"Nucleic Acids Res"},{"key":"10.14348\/molcells.2017.2295_bib17","doi-asserted-by":"crossref","first-page":"5850","DOI":"10.1016\/j.febslet.2005.08.071","article-title":"Small RNA asymmetry in RNAi: function in RISC assembly and gene regulation","volume":"579","author":"Hutvagner","year":"2005","journal-title":"FEBS Lett"},{"key":"10.14348\/molcells.2017.2295_bib18","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1016\/S0168-9525(00)02093-X","article-title":"Repbase update: a database and an electronic journal of repetitive elements","volume":"16","author":"Jurka","year":"2000","journal-title":"Trends Genet"},{"key":"10.14348\/molcells.2017.2295_bib19","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1007\/BF00057588","article-title":"Identification of new medium reiteration frequency repeats in the genomes of Primates, Rodentia and Lagomorpha","volume":"98","author":"Jurka","year":"1996","journal-title":"Genetica"},{"key":"10.14348\/molcells.2017.2295_bib20","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1159\/000084979","article-title":"Repbase Update, a database of eukaryotic repetitive elements","volume":"110","author":"Jurka","year":"2005","journal-title":"Cytogenet Genome Res"},{"key":"10.14348\/molcells.2017.2295_bib21","doi-asserted-by":"crossref","first-page":"e93662","DOI":"10.1371\/journal.pone.0093662","article-title":"Identification and characterization of microRNAs in normal equine tissues by next generation sequencing","volume":"9","author":"Kim","year":"2014","journal-title":"PLoS One"},{"key":"10.14348\/molcells.2017.2295_bib22","doi-asserted-by":"crossref","first-page":"D68","DOI":"10.1093\/nar\/gkt1181","article-title":"miRBase: annotating high confidence microRNAs using deep sequencing data","volume":"42","author":"Kozomara","year":"2014","journal-title":"Nucleic Acids Res"},{"key":"10.14348\/molcells.2017.2295_bib23","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1038\/nm.2129","article-title":"Derepression of an endogenous long terminal repeat activates the CSF1R proto-oncogene in human lymphoma","volume":"16","author":"Lamprecht","year":"2010","journal-title":"Nat Med"},{"key":"10.14348\/molcells.2017.2295_bib24","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1038\/35057062","article-title":"Initial sequencing and analysis of the human genome","volume":"409","author":"Lander","year":"2001","journal-title":"Nature"},{"key":"10.14348\/molcells.2017.2295_bib25","doi-asserted-by":"crossref","first-page":"4051","DOI":"10.1038\/sj.emboj.7600385","article-title":"MicroRNA genes are transcribed by RNA polymerase II","volume":"23","author":"Lee","year":"2004","journal-title":"EMBO J"},{"key":"10.14348\/molcells.2017.2295_bib26","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1038\/nature05453","article-title":"Genome-wide atlas of gene expression in the adult mouse brain","volume":"445","author":"Lein","year":"2007","journal-title":"Nature"},{"key":"10.14348\/molcells.2017.2295_bib27","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1007\/s13238-012-2081-y","article-title":"MicroRNA-548 down-regulates host antiviral response via direct targeting of IFN-\u03bb1","volume":"4","author":"Li","year":"2013","journal-title":"Protein Cell"},{"key":"10.14348\/molcells.2017.2295_bib28","doi-asserted-by":"crossref","first-page":"679563","DOI":"10.1155\/2012\/679563","article-title":"Genome-wide analysis of mir-548 gene family reveals evolutionary and functional implications","volume":"2012","author":"Liang","year":"2012","journal-title":"J Biomed Biotechnol"},{"key":"10.14348\/molcells.2017.2295_bib29","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1101\/sqb.2006.71.050","article-title":"Substrate selectivity of exportin 5 and Dicer in the biogenesis of microRNAs","volume":"71","author":"Lund","year":"2006","journal-title":"Cold Spring Harb Symp Quant Biol"},{"key":"10.14348\/molcells.2017.2295_bib30","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1248\/bpb.28.886","article-title":"Tissue-specific mRNA expression profiles of human toll-like receptors and related genes","volume":"28","author":"Nishimura","year":"2005","journal-title":"Biol Pharm Bull"},{"key":"10.14348\/molcells.2017.2295_bib31","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1093\/gbe\/evq009","article-title":"Origins and evolution of microRNA genes in Drosophila species","volume":"2","author":"Nozawa","year":"2010","journal-title":"Genome Biol Evol"},{"key":"10.14348\/molcells.2017.2295_bib32","doi-asserted-by":"crossref","first-page":"3087","DOI":"10.1158\/0008-5472.CAN-03-3773","article-title":"Identification and characterization of a novel gene, C13orf25, as a target for 13q31\u2013q32 amplification in malignant lymphoma","volume":"64","author":"Ota","year":"2004","journal-title":"Cancer Res"},{"key":"10.14348\/molcells.2017.2295_bib33","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/s10142-013-0313-8","article-title":"Transposable element-associated microRNA hairpins produce 21-nt sRNAs integrated into typical microRNA pathways in rice","volume":"13","author":"Ou-Yang","year":"2013","journal-title":"Funct Integr Genomics"},{"key":"10.14348\/molcells.2017.2295_bib34","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1101\/gr.5826307","article-title":"The evolutionary history of human DNA transposons: evidence for intense activity in the primate lineage","volume":"17","author":"Pace","year":"2007","journal-title":"Genome Res"},{"key":"10.14348\/molcells.2017.2295_bib35","doi-asserted-by":"crossref","first-page":"950","DOI":"10.14348\/molcells.2015.0121","article-title":"Gain of a new exon by a lineage-specific alu element-integration event in the BCS1L gene during primate evolution","volume":"38","author":"Park","year":"2015","journal-title":"Mol Cells"},{"key":"10.14348\/molcells.2017.2295_bib36","doi-asserted-by":"crossref","first-page":"e1003211","DOI":"10.1371\/journal.pgen.1003211","article-title":"Genome-wide analysis reveals selection for important traits in domestic horse breeds","volume":"9","author":"Petersen","year":"2013","journal-title":"PLoS Genet"},{"key":"10.14348\/molcells.2017.2295_bib37","doi-asserted-by":"crossref","first-page":"e203","DOI":"10.1371\/journal.pone.0000203","article-title":"A family of human microRNA genes from miniature inverted-repeat transposable elements","volume":"2","author":"Piriyapongsa","year":"2007","journal-title":"PLoS One"},{"key":"10.14348\/molcells.2017.2295_bib38","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1261\/rna.916708","article-title":"Dual coding of siRNAs and miRNAs by plant transposable elements","volume":"14","author":"Piriyapongsa","year":"2008","journal-title":"RNA"},{"key":"10.14348\/molcells.2017.2295_bib39","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1534\/genetics.107.072553","article-title":"Origin and evolution of human microRNAs from transposable elements","volume":"176","author":"Piriyapongsa","year":"2007","journal-title":"Genetics"},{"key":"10.14348\/molcells.2017.2295_bib40","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1007\/s10038-008-0279-x","article-title":"Global correlation analysis for micro-RNA and mRNA expression profiles in human cell lines","volume":"53","author":"Ruike","year":"2008","journal-title":"J Hum Genet"},{"key":"10.14348\/molcells.2017.2295_bib41","first-page":"83","article-title":"MicroRNAs: processing, maturation, target recognition and regulatory functions","volume":"3","author":"Shukla","year":"2011","journal-title":"Mol Cell Pharmacol"},{"key":"10.14348\/molcells.2017.2295_bib42","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1186\/gb-2003-4-7-403","article-title":"EST analyses predict the existence of a population of chimeric microRNA precursor-mRNA transcripts expressed in normal human and mouse tissues","volume":"4","author":"Smalheiser","year":"2003","journal-title":"Genome Biol"},{"key":"10.14348\/molcells.2017.2295_bib43","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/j.tig.2005.04.008","article-title":"Mammalian microRNAs derived from genomic repeats","volume":"21","author":"Smalheiser","year":"2005","journal-title":"Trends Genet"},{"key":"10.14348\/molcells.2017.2295_bib44","series-title":"RepeatMasker Open-3.0. 2004","author":"Smit","year":"2004"},{"key":"10.14348\/molcells.2017.2295_bib45","doi-asserted-by":"crossref","first-page":"1863","DOI":"10.1093\/nar\/21.8.1863","article-title":"Identification of a new, abundant superfamily of mammalian LTR-transposons","volume":"21","author":"Smit","year":"1993","journal-title":"Nucleic Acids Res"},{"key":"10.14348\/molcells.2017.2295_bib46","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1126\/science.1178158","article-title":"Genome sequence, comparative analysis, and population genetics of the domestic horse","volume":"326","author":"Wade","year":"2009","journal-title":"Science"},{"key":"10.14348\/molcells.2017.2295_bib47","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1186\/1471-2148-10-346","article-title":"Origin and evolution of a placental-specific microRNA family in the human genome","volume":"10","author":"Yuan","year":"2010","journal-title":"BMC Evol Biol"},{"key":"10.14348\/molcells.2017.2295_bib48","doi-asserted-by":"crossref","first-page":"e17666","DOI":"10.1371\/journal.pone.0017666","article-title":"MicroRNA genes derived from repetitive elements and expanded by segmental duplication events in mammalian genomes","volume":"6","author":"Yuan","year":"2011","journal-title":"PLoS One"},{"key":"10.14348\/molcells.2017.2295_bib49","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1073\/pnas.97.3.1160","article-title":"Recent, extensive, and preferential insertion of members of the miniature inverted-repeat transposable element family Heartbreaker into genic regions of maize","volume":"97","author":"Zhang","year":"2000","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.14348\/molcells.2017.2295_bib50","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.fertnstert.2011.04.053","article-title":"A single nucleotide polymorphism in a miR-1302 binding site in CGA increases the risk of idiopathic male infertility","volume":"96","author":"Zhang","year":"2011","journal-title":"Fertil Steril"},{"key":"10.14348\/molcells.2017.2295_bib51","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.ygeno.2009.04.006","article-title":"In silico detection and characteristics of novel microRNA genes in the Equus caballus genome using an integrated ab initio and comparative genomic approach","volume":"94","author":"Zhou","year":"2009","journal-title":"Genomics"}],"container-title":["Molecules and Cells"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S101684782300609X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S101684782300609X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T17:52:29Z","timestamp":1760896349000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S101684782300609X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4]]},"references-count":51,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,4]]}},"alternative-id":["S101684782300609X"],"URL":"https:\/\/doi.org\/10.14348\/molcells.2017.2295","relation":{},"ISSN":["1016-8478"],"issn-type":[{"value":"1016-8478","type":"print"}],"subject":[],"published":{"date-parts":[[2017,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Identification and Expression of Equine MER-Derived miRNAs","name":"articletitle","label":"Article Title"},{"value":"Molecules and Cells","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.14348\/molcells.2017.2295","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2017 THE AUTHORS. Published by Elsevier Inc on behalf of the Korean Society for Molecular and Cellular Biology. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}