{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T19:51:50Z","timestamp":1780516310246,"version":"3.54.1"},"reference-count":27,"publisher":"Korean Society of Ultrasound in Medicine","issue":"1","license":[{"start":{"date-parts":[[2025,11,19]],"date-time":"2025-11-19T00:00:00Z","timestamp":1763510400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"funder":[{"DOI":"10.13039\/100017141","name":"Samsung Medison","doi-asserted-by":"publisher","award":["0620243920"],"award-info":[{"award-number":["0620243920"]}],"id":[{"id":"10.13039\/100017141","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["e-ultrasonography.org"],"crossmark-restriction":true},"short-container-title":["Ultrasonography"],"published-print":{"date-parts":[[2026,1,1]]},"abstract":"<jats:p>Purpose: This study evaluated the clinical utility of a fully automated two-dimensional shear wave elastography (2D-SWE) method incorporating automated frame selection and region-of-interest (ROI) placement algorithms in participants with diffuse liver disease. The analysis assessed examination time and reproducibility compared with semi-automated and manual methods.Methods: This prospective study included 40 participants who underwent liver stiffness measurements with a Samsung Medison ultrasound system using three methods: fully automated (automated frame selection via a reliability indicator derived from elasticity uniformity and the reliability measurement index, with automated ROI placement); semi-automated (automated frame selection with manual ROI placement); and manual (fully operator-controlled). Examination time and inter-method (n=40), intra-observer (n=21), and inter-observer (n=15) variabilities were analyzed using analysis of variance, paired t-tests, and intraclass correlation coefficients (ICCs). All participants underwent comparative measurements with a Canon i800 system for cross-platform analysis.Results: One technical failure each occurred during the intra-observer and cross-platform measurement sessions. Fully automated measurement significantly reduced total examination time (14.38\u00b15.01 seconds) compared to semi-automated (30.46\u00b17.11 seconds, P&amp;lt;0.001) and manual (33.05\u00b17.10 seconds, P&amp;lt;0.001) measurements. No significant differences in liver stiffness were observed among methods (P=0.556). Inter-method agreement was excellent (ICC, 0.997). Intra-observer and inter-observer agreements were also excellent with the fully automated method (ICCs, 0.971 and 0.984, respectively). Good cross-platform agreement with the Canon system was observed (ICC, 0.833).Conclusion: Fully automated 2D-SWE markedly reduces examination time while maintaining high reproducibility in liver stiffness assessment.<\/jats:p>","DOI":"10.14366\/usg.25161","type":"journal-article","created":{"date-parts":[[2025,11,19]],"date-time":"2025-11-19T06:13:31Z","timestamp":1763532811000},"page":"69-79","update-policy":"https:\/\/doi.org\/10.14366\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Fully automated frame selection and region-of-interest placement in 2D shear wave elastography: reduced examination time with comparable reproducibility in diffuse liver 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