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Di\u00e1rio Oficial da Uni\u00e3o, se\u00e7\u00e3o 1, Poder Executivo, Bras\u00edlia, DF, p. 75, 22 abr. 2010. Dispon\u00edvel em: <http:\/\/bvsms.saude.gov.br\/bvs\/saudelegis\/gm\/2010\/prt0886_20_04_2010.html>. Acesso em: 10 nov. 2018.","key":"ref29"},{"unstructured":"31. BRASIL. Minist\u00e9rio da Sa\u00fade. Resolu\u00e7\u00e3o da Diretoria Colegiada - RDC n\u00ba 18, de 03 de abril de 2013. Disp\u00f5e sobre as boas pr\u00e1ticas de processamento e armazenamento de plantas medicinais, prepara\u00e7\u00e3o e dispensa\u00e7\u00e3o de produtos magistrais e oficinais de plantas medicinais e fitoter\u00e1picos em farm\u00e1cias vivas no \u00e2mbito do Sistema \u00danico de Sa\u00fade (SUS). Bras\u00edlia: Minist\u00e9rio da Sa\u00fade, 2013c. Dispon\u00edvel em: <http:\/\/bvsms.saude.gov.br\/bvs\/saudelegis\/anvisa\/2013\/rdc0018_03_04_2013.pdf>. Acesso em: 10 nov. 2018.","key":"ref30"},{"unstructured":"32. BRASIL. Minist\u00e9rio da Sa\u00fade. Secretaria de Aten\u00e7\u00e3o \u00e0 Sa\u00fade. Departamento de Aten\u00e7\u00e3o B\u00e1sica. Acolhimento \u00e0 demanda espont\u00e2nea: queixas mais comuns na aten\u00e7\u00e3o b\u00e1sica. Bras\u00edlia: Minist\u00e9rio da Sa\u00fade, 2013a. (Cadernos de Aten\u00e7\u00e3o B\u00e1sica, n. 28, v. I). Dispon\u00edvel em: <http:\/\/bvsms.saude.gov.br\/bvs\/publicacoes\/acolhimento_demanda_espontanea_cab28v1.pdf>. Acesso em: 10 nov. 2018.","key":"ref31"},{"unstructured":"33. BRASIL. Minist\u00e9rio da Sa\u00fade. Secretaria de Aten\u00e7\u00e3o \u00e0 Sa\u00fade. Departamento de Aten\u00e7\u00e3o B\u00e1sica. Acolhimento \u00e0 demanda espont\u00e2nea. Bras\u00edlia: Minist\u00e9rio da Sa\u00fade, 2013b. (Cadernos de Aten\u00e7\u00e3o B\u00e1sica, n. 28, v. II). Dispon\u00edvel em: <http:\/\/www.saude.sp.gov.br\/resources\/humanizacao\/biblioteca\/documentos-norteadores\/cadernos_de_atencao_basica_-_volume_ii.pdf>. Acesso em: 10 nov. 2018.","key":"ref32"},{"unstructured":"34. 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BYTZER, P.; TALLEY, N. J. Dyspepsia. Annals of Internal Medicine, Philadelphia, v. 134, n. 9 Pt 2, p. 815-822, May 2001.","key":"ref36","DOI":"10.7326\/0003-4819-134-9_Part_2-200105011-00004"},{"doi-asserted-by":"publisher","unstructured":"38. CABRAL, A. L. L. V. et al. Itiner\u00e1rios terap\u00eauticos: o estado da arte da produ\u00e7\u00e3o cient\u00edfica no Brasil. Ci\u00eancia & Sa\u00fade Coletiva, Rio de Janeiro, v. 16, n. 11, p. 4433-4442, nov. 2011. Dispon\u00edvel em: <http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S1413-81232011001200016&nrm=iso>. Acesso em: 10 nov. 2018.","key":"ref37","DOI":"10.1590\/S1413-81232011001200016"},{"unstructured":"39. CAMILLERI, M. Gastroparesis: Etiology, clinical manifestations, and diagnosis. Last updated: Sep. 24, 2018. In: POST, T. W. (ed.). UpToDate. Data base. Waltham, MA: UpToDate, 2018.","key":"ref38"},{"unstructured":"40. CARLINI, E. A.; FROCHTENGARTEN, M. L. Toxicologia cl\u00ednica (Fase I) da espinheira-santa (Maytenus ilicifolia). In: CENTRAL DE MEDICAMENTOS (Brasil). Estudo de a\u00e7\u00e4o anti\u00falcera g\u00e1strica de plantas brasileiras (maytev\u00edrus ilicifolia \"espinheira-santa\" e outras). Bras\u00edlia: Central de Medicamentos, 1988. p. 67-73.","key":"ref39"},{"doi-asserted-by":"publisher","unstructured":"41. CARVALHO, R. V. B. et al. Food Intolerance, Diet Composition, and Eating Patterns in Functional Dyspepsia Patients. Digestive Diseases and Sciences, New York, v. 55, n. 1, p. 60-65, Jan. 2010.","key":"ref40","DOI":"10.1007\/s10620-008-0698-8"},{"unstructured":"42. CASTRO, L. L. C. Fundamentos de farmacoepidemiologia. Cuiab\u00e1: Grupuran, 2000.","key":"ref41"},{"unstructured":"43. CECILIO, L. C. O. As necessidades de sa\u00fade como conceito estruturalmente na luta pela integralidade e equidade na aten\u00e7\u00e3o em sa\u00fade. In: PINHERO, R.; MATTOS, R. A. (ed.). 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Renal Failure, London, v. 37, n. 7, p. 1237-1241, Aug. 2015.","key":"ref45","DOI":"10.3109\/0886022X.2015.1057800"},{"unstructured":"47. COMIT\u00ca INTERNACIONAL DE CLASSIFICA\u00c7\u00c3O DA ORGANIZA\u00c7\u00c3O MUNDIAL DE ASSOCIA\u00c7\u00d5ES NACIONAIS, ACADEMIAS E ASSOCIA\u00c7\u00d5ES ACAD\u00caMICAS DE CL\u00cdNICOS GERAIS\/M\u00c9DICOS DE FAM\u00cdLIA. Classifica\u00e7\u00e3o Internacional de Aten\u00e7\u00e3o Prim\u00e1ria 2. ed. (CIAP2). Florian\u00f3polis: Sociedade Brasileira de Medicina de Fam\u00edlia e Comunidade, 2009. Dispon\u00edvel em: <http:\/\/www.sbmfc.org.br\/media\/file\/CIAP%202\/CIAP%20Brasil_atualizado.pdf>. Acesso em: 10 nov. 2018.","key":"ref46"},{"unstructured":"48. CONCEITOS elementares de estat\u00edstica. [S.l.: s.n.], 2003. Dispon\u00edvel em: <http:\/\/www.inf.ufsc.br\/~marcelo.menezes.reis\/intro.html>. Acesso em: 12 ago. 2016.","key":"ref47"},{"unstructured":"49. CONSELHO FEDERAL DE FARM\u00c1CIA (Brasil). 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Acesso em: 11 jun. 2019.","key":"ref52"},{"unstructured":"54. CORMAN, M. L. et al. Corman cirurgia colorretal. 6. ed. Rio de Janeiro: Revinter, 2017.","key":"ref53"},{"unstructured":"55. CORRER, C.; OTUKI, M. A pr\u00e1tica farmac\u00eautica na farm\u00e1cia comunit\u00e1ria. Porto Alegre: Artmed, 2013.","key":"ref54"},{"doi-asserted-by":"publisher","unstructured":"56. COSTA, J. A. C. D.; VIEIRA-NETO, O. M.; MOYS\u00c9S NETO, M. Insufici\u00eancia Renal Aguda. Medicina, Ribeir\u00e3o Preto, v. 36, n. 2\/4, p. 307-324, dez. 2003.","key":"ref55","DOI":"10.11606\/issn.2176-7262.v36i2\/4p307-324"},{"doi-asserted-by":"publisher","unstructured":"57. COUTINHO, E. S. F.; CUNHA, G. M. D. Conceitos b\u00e1sicos de epidemiologia e estat\u00edstica para a leitura de ensaios cl\u00ednicos controlados. Revista Brasileira de Psiquiatria, S\u00e3o Paulo, v. 27, p. 146-151, jun. 2005. Dispon\u00edvel em: <http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S1516-44462005000200015&nrm=iso>. Acesso em: 10 nov. 2018.","key":"ref56","DOI":"10.1590\/S1516-44462005000200015"},{"doi-asserted-by":"publisher","unstructured":"58. DABOS, K. J. et al. Is Chios mastic gum effective in the treatment of functional dyspepsia? A prospective randomised double-blind placebo controlled trial. Journal of Ethnopharmacology, Limerick, v. 127, n. 2, p. 205-209, Feb. 2010.","key":"ref57","DOI":"10.1016\/j.jep.2009.11.021"},{"unstructured":"59. DAWSON, B.; TRAPP, R. G. Bioestat\u00edstica b\u00e1sica e cl\u00ednica. Tradu\u00e7\u00e3o de Carla de Mello Vorsatz. 3. ed. Rio de Janeiro: McGraw-Hill, 2003.","key":"ref58"},{"unstructured":"60. DEL VALLE, J.; CHEY, W. D.; SCBEIMAN, J. M. Acid peptic disorders. In: YAMADA, I. (ed.) et al. Textbook of Gastroenterology. 4th ed. Philadelphia: Lippincott: Williams & Williams, 2003. p. 321-376.","key":"ref59"},{"doi-asserted-by":"publisher","unstructured":"61. DELANEY, B. et al. Initial management strategies for dyspepsia. 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Fetal and neonatal edition, London, v. 81, n. 3, p. F201-5, Nov. 1999.","key":"ref70","DOI":"10.1136\/fn.81.3.F201"},{"unstructured":"72. FARLEX PARTNER MEDICAL DICTIONARY. Bolus. [S.l.], 2018a. Dispon\u00edvel em: <https:\/\/medical-dictionary.thefreedictionary.com\/bolus>. Acesso em: 10 nov. 2018.","key":"ref71"},{"unstructured":"73. FARLEX PARTNER MEDICAL DICTIONARY. Electrolyte Disorders. [S.l.], 2018b. Dispon\u00edvel em: <https:\/\/medical-dictionary.thefreedictionary.com\/Electrolyte+disturbance>. Acesso em: 10 nov. 2018.","key":"ref72"},{"unstructured":"74. FARREL, B. et al. Deprescribing proton pump inhibitors. Canadian Family Physician, Don Mills, v. 63, n. 3, p. 354-364, May 2017.","key":"ref73"},{"doi-asserted-by":"publisher","unstructured":"75. FEINLE-BISSET, C. Upper gastrointestinal sensitivity to meal-related signals in adult humans - relevance to appetite regulation and gut symptoms in health, obesity and functional dyspepsia. Physiology & Behavior, New York, v. 162, p. 69-82, Aug. 2016.","key":"ref74","DOI":"10.1016\/j.physbeh.2016.03.021"},{"doi-asserted-by":"publisher","unstructured":"76. FELD, L.; CIFU, A. S. Management of Dyspesia. JAMA, Chicago, v. 319, n. 17, p. 1816-1817, May 2018.","key":"ref75","DOI":"10.1001\/jama.2018.3435"},{"unstructured":"77. FERREIRA, A. B. H. Dicion\u00e1rio da l\u00edngua portuguesa. 5. ed. Curitiba: Positivo, 2010.","key":"ref76"},{"doi-asserted-by":"publisher","unstructured":"78. FERREIRA, P. M. et al. A lyophilized aqueous extract of Maytenus ilicifolia leaves inhibits histamine-mediated acid secretion in isolated frog gastric mucosa. Planta, Berlin, v. 219, n. 2, p. 319-324, June 2004.","key":"ref77","DOI":"10.1007\/s00425-004-1222-9"},{"unstructured":"79. FOOD AND DRUG ADMINSTRATION. Over-The-Counter (OTC) Heartburn Treatment. Silver Spring: FDA, 2018. Dispon\u00edvel em: <https:\/\/www.fda.gov\/drugs\/resourcesforyou\/consumers\/ucm511944.htm>. Acesso em: 11 jun. 2019.","key":"ref78"},{"doi-asserted-by":"publisher","unstructured":"80. FORD, A. C. et al. Global prevalence of, and risk factors for, uninvestigated dyspepsia: a meta-analysis. Gut, London, v. 64, n. 7, p. 1049-1057, July 2015.","key":"ref79","DOI":"10.1136\/gutjnl-2014-307843"},{"doi-asserted-by":"publisher","unstructured":"81. GEEVASINGA, N. et al. Proton Pump Inhibitors and Acute Interstitial Nephritis. Clinical Gastroenterology and Hepatology, Philadelphia, v. 4, n. 5, p. 597-604. May 2006.","key":"ref80","DOI":"10.1016\/j.cgh.2005.11.004"},{"doi-asserted-by":"publisher","unstructured":"82. GEOCZE, S. et al. Tratamento de pacientes portadores com dispepsia alta ou \u00falcera p\u00e9ptica com prepara\u00e7\u00f5es de espinheira-santa (Maytenus ilicifolia). Publica\u00e7\u00e3o CEME, [S.l.], n. 2, p. 75-87, 1988 apud SANTOS-OLIVEIRA, R.; COULAUD-CUNHA, S.; COLA\u00c7O, W. 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Treatment with cimetidine, antacid, or placebo in patients with dyspepsia of unknown origin. Scandinavian Journal of Gastroenterology, London, v. 23, n. 1, p. 7-18, Jan. 1988.","key":"ref84","DOI":"10.3109\/00365528809093840"},{"doi-asserted-by":"publisher","unstructured":"86. GULMEZ, S. E. et al. Use of proton pump inhibitors and the risk of community-acquired pneumonia: a population-based case-control study. Archives of Internal Medicine, Chicago, v. 167, n. 9, p. 950-955, May 2007.","key":"ref85","DOI":"10.1001\/archinte.167.9.950"},{"doi-asserted-by":"publisher","unstructured":"87. HAENISCH, B. et al. Risk of dementia in elderly patients with the use of proton pump inhibitors. European Archives of Psychiatry and Clinical Neuroscience, Berlin, v. 265, n. 5, p. 419-428, Aug. 2015.","key":"ref86","DOI":"10.1007\/s00406-014-0554-0"},{"doi-asserted-by":"publisher","unstructured":"88. HANSEN, B.; BRUSERUD, \u00d8. Hypomagnesemia as a potentially life-threatening adverse effect of omeprazole. Oxford Medical Case Reports, Oxford, v. 2016, n. 7, p. 147-149, July 2016.","key":"ref87","DOI":"10.1093\/omcr\/omw062"},{"doi-asserted-by":"publisher","unstructured":"89. HOLTMANN, G. et al. Efficacy of artichoke leaf extract in the treatment of patients with functional dyspepsia: a six-week placebo-controlled, double-blind, multicentre trial. Alimentary Pharmacology & Therapeutics, Oxford, v. 18, n. 11-12, p. 1099-1105, Dec. 2003.","key":"ref88","DOI":"10.1046\/j.1365-2036.2003.01767.x"},{"unstructured":"90. HOUAISS, A.; VILLAR, M. S. Dicion\u00e1rio Houaiss da L\u00edngua Portuguesa. Rio de Janeiro: Objetiva, 2011.","key":"ref89"},{"unstructured":"91. HOWDEN, C. W.; CHEY, W. D. Gastroesophageal reflux disease. The Journal of Family Practice, Parsippany, v. 52, n. 3, p. 240-247, Mar. 2003.","key":"ref90"},{"doi-asserted-by":"publisher","unstructured":"92. HUNT, R. et al. Coping with common gastrointestinal symptoms in the community: a global perspective on heartburn, constipation, bloating, and abdominal pain\/discomfort May 2013. Journal of Clinical Gastroenterology, New York, v. 48, n. 7, p. 567-578, Aug. 2014.","key":"ref91","DOI":"10.1097\/MCG.0000000000000141"},{"doi-asserted-by":"publisher","unstructured":"93. INADOMI, J. M. et al. Step-down management of gastroesophageal reflux disease. Gastroenterology, Philadelphia, v. 121, n. 5, p. 1095-1100, Nov. 2001.","key":"ref92","DOI":"10.1053\/gast.2001.28649"},{"doi-asserted-by":"publisher","unstructured":"94. JENA, A. B.; SUN, E.; GOLDMAN, D. P. Confounding in the association of proton pump inhibitor use with risk of community-acquired pneumonia. Journal of General Internal Medicine, Philadelphia, v. 28, n. 2, p. 223-230, Feb. 2013.","key":"ref93","DOI":"10.1007\/s11606-012-2211-5"},{"doi-asserted-by":"publisher","unstructured":"95. JIANG, S. M. et al. Unhealthy dietary behavior in refractory functional dyspepsia: a multicenter prospective investigation in China. Journal of Digestive Diseases, Carlton, v. 15, n. 12, p. 654-659, Dec. 2014.","key":"ref94","DOI":"10.1111\/1751-2980.12199"},{"unstructured":"96. JONES, R. M.; ROSPOND, R. M. Patient Assessment in Pharmacy Pratice. Philadelphia: Lippincott: Williams & Wilkins, 2003.","key":"ref95"},{"unstructured":"97. KAHRILAS, P. J. Medical management of gastroesophageal reflux disease in adults. Last updated: Mar. 28, 2018. In: POST, T. W. (ed.). UpToDate. Data base. Waltham, MA: UpToDate, 2018.","key":"ref96"},{"doi-asserted-by":"publisher","unstructured":"98. KALTENBACH, T.; CROCKETT, S.; GERSON, L. B. Are lifestyle measures effective in patients with gastroesophageal reflux disease? An evidence-based approach. 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Acesso em: 11 jun. 2019.","key":"ref128","DOI":"10.1016\/S0140-6736(06)68932-0"},{"unstructured":"130. MORAES, E. N. A arte da (des)prescri\u00e7\u00e3o no idoso: a dualidade terap\u00eautica. Belo Horizonte: Folium, 2018.","key":"ref129"},{"doi-asserted-by":"publisher","unstructured":"131. MORAES-FILHO, J. P. P. et al. Brazilian Consensus on gastroesophageal reflux disease: proposals for assessment, classification, and management. Arquivos de Gastroenterologia, S\u00e3o Paulo, v. 47, n. 1, p. 99-115, jan.\/mar. 2010. Dispon\u00edvel em: <http:\/\/www.scielo.br\/pdf\/ag\/v47n1\/v47n1a17.pdf>. Acesso em: 11 jun. 2019.","key":"ref130","DOI":"10.1590\/S0004-28032010000100017"},{"doi-asserted-by":"publisher","unstructured":"132. MOSEGUI, G. B. G. et al. Avalia\u00e7\u00e3o da qualidade do uso de medicamentos em idosos. 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International Journal of Epidemiology, London, v. 32, n. 4, p. 645-650, Aug. 2003.","key":"ref134","DOI":"10.1093\/ije\/dyg108"},{"doi-asserted-by":"publisher","unstructured":"136. MYLES, P. R. et al. Risk of community-acquired pneumonia and the use of statins, ace inhibitors and gastric acid suppressants: a population-based case-control study. Pharmacoepidemiology and Drug Safety, Chichester, v. 18, n. 4, p. 269-275, Apr. 2009.","key":"ref135","DOI":"10.1002\/pds.1715"},{"doi-asserted-by":"publisher","unstructured":"137. NALIBOFF, B. D. et al. The effect of life stress on symptoms of heartburn. Psychosomatic Medicine, Hagerstown, v. 66, n. 3, p. 426-434, May 2004.","key":"ref136","DOI":"10.1097\/01.psy.0000124756.37520.84"},{"doi-asserted-by":"publisher","unstructured":"138. NANDURKAR, S. et al. Relationship between body mass index, diet, exercise and gastro-oesophageal reflux symptoms in a community. 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Dispon\u00edvel em: <http:\/\/www.palliativecareggc.org.uk\/wp-content\/uploads\/2013\/10\/245378-2-Antacid-Sept-2015.pdf>. Acesso em: 11 jun. 2019.","key":"ref140"},{"unstructured":"142. NHS. Indigestion and heartburn in pregnancy: your pregnancy and baby guide. [S.l.]: NHS, 2017. Dispon\u00edvel em: <https:\/\/www.nhs.uk\/conditions\/pregnancy-and-baby\/indigestion-heartburn-pregnant\/>. Acesso em: 25 de mar\u00e7o de 2018.","key":"ref141"},{"unstructured":"143. NOGUEIRA, R. P. O. Determina\u00e7\u00e3o social da doen\u00e7a e reforma sanit\u00e1ria. Rio de Janeiro: Cebes, 2010.","key":"ref142"},{"unstructured":"144. NUMANS, M. et al. Dispepsia. Rio de Janeiro: SBMFC, 2014. p. 1-8. Dispon\u00edvel em: <http:\/\/sbmfc.org.br\/media\/NHG%204%20Dispepsia(1).pdf>. Acesso em: 11 jun. 2019.","key":"ref143"},{"unstructured":"145. NUTRITION SUPPORT DIETITIANS. Norfolk and Norwich University Hospitals NHS Foundation Trust. Patient information leaflet: Indigestion and Acid Reflux. Colney Lane: NHS, 2018. Dispon\u00edvel em: <http:\/\/www.nnuh.nhs.uk\/publication\/download\/symptom-control-indigestion-and-acid-reflux-v1\/>. Acesso em: 11 jun. 2019.","key":"ref144"},{"doi-asserted-by":"publisher","unstructured":"146. OLENNIKOV, D. N. et al. Iridoids and Flavonoids of Four Siberian Gentians: Chemical Profile and Gastric Stimulatory Effect. Molecules, Basel, v. 20, n. 10, p.19172-19188, Oct. 2015.","key":"ref145","DOI":"10.3390\/molecules201019172"},{"doi-asserted-by":"publisher","unstructured":"147. OLIVER, K.; DAVIES, G.; DETTMAR, P. Diet and lifestyle as trigger factors for the onset of heartburn. Nursing Standard, London, v. 25, n. 36, p. 44-48, May 2011.","key":"ref146","DOI":"10.7748\/ns.25.36.44.s50"},{"unstructured":"148. PATON, S. Cost-effective treatment of gastro-oesophageal reflux disease - a comparison of two therapies commonly used in general practice. British Journal of Medical Economics, [S.l.], v. 8, n. 2, p. 85-95, 1995.","key":"ref147"},{"doi-asserted-by":"publisher","unstructured":"149. PEHL, C. et al. Effect of caloric density of a meal on lower oesophageal sphincter motility and gastro-oesophageal reflux in healthy subjects. Alimentary Pharmacology and Therapeutics, Oxford, v. 15, n. 2, p. 233-239, Feb. 2001.","key":"ref148","DOI":"10.1046\/j.1365-2036.2001.00919.x"},{"doi-asserted-by":"publisher","unstructured":"150. PEHL, C. et al. Gastroesophageal reflux induced by white wine: the role of acid clearance and \"rereflux\". The American Journal of Gastroenterology, New York, v. 97, n. 3, p. 561-567, Mar. 2002.","key":"ref149","DOI":"10.1016\/S0002-9270(01)04092-8"},{"doi-asserted-by":"crossref","unstructured":"151. PHUPONG, V.; HANPRASERTPONG, T. Interventions for heartburn in pregnancy. The Cochrane Database Systematic Revews, Chichester, n. 9, p. Cd011379, Sep. 2015. Dispon\u00edvel em: <https:\/\/www.cochranelibrary.com\/cdsr\/doi\/10.1002\/14651858.CD011379.pub2\/epdf\/full>. Acesso em: 10 nov. 2018.","key":"ref150","DOI":"10.1002\/14651858.CD011379"},{"doi-asserted-by":"publisher","unstructured":"152. PILICHIEWICZ, A. N. et al. Relationship between symptoms and dietary patterns in patients with functional dyspepsia. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, Philadelphia, v. 7, n. 3, p. 317-22, Mar. 2009.","key":"ref151","DOI":"10.1016\/j.cgh.2008.09.007"},{"unstructured":"153. PILLAY, N. et al. The economic burden of minor ailments on the National Health Service (NHS) in the UK. SelfCare, [S.l.], v. 1, n. 3, p. 105-116, 2010.","key":"ref152"},{"unstructured":"154. PINHEIRO, R. Cuidado em sa\u00fade. Rio de Janeiro: Dicion\u00e1rio da Educa\u00e7\u00e3o Profissional em Sa\u00fade, 2009. Dispon\u00edvel em: <http:\/\/www.epsjv.fiocruz.br\/dicionario\/verbetes\/cuisau.html>. Acesso em: 10 nov. 2018.","key":"ref153"},{"unstructured":"155. PORTO, C. C. Semiologia m\u00e9dica. 6. ed. Rio de Janeiro: Guanabara Koogan, 2009.","key":"ref154"},{"unstructured":"156. PREFEITURA MUNICIPAL DE S\u00c3O BERNARDO DO CAMPO. Secretaria de Sa\u00fade. Diretrizes para o manejo cl\u00ednico de pessoas com doen\u00e7as gastrointestinais. S\u00e3o Bernardo do Campo (SP): Prefeitura Municipal de S\u00e3o Bernanrdo do Campo, 2014. Dispon\u00edvel em: <http:\/\/www.saobernardo.sp.gov.br\/documents\/10181\/26510\/gastrointestinais.pdf\/5ac2d596-5ffb-43e7-a31a-63137e9bc711>. Acesso em: 11 jun. 2019.","key":"ref155"},{"unstructured":"157. PRADO E SILVA, A. et al. (orgs.). Grande Dicion\u00e1rio Brasileiro Melhoramentos. 8. ed. rev. amp. S\u00e3o Paulo: Melhoramentos, 1975. 5 v.","key":"ref156"},{"doi-asserted-by":"publisher","unstructured":"158. RA, A.; TOBE, S. W. Acute interstitial nephritis due to pantoprazole. The Annals of Pharmacotherapy, Thousand Oaks, v. 38, n. 1, p. 41-45, Jan. 2004.","key":"ref157","DOI":"10.1345\/aph.1D085"},{"doi-asserted-by":"publisher","unstructured":"159. RECKER, R. R. Calcium absorption and achlorhydria. The New England Journal of Medicine, Boston, v. 313, n. 2, p. 70-73, July 1985.","key":"ref158","DOI":"10.1056\/NEJM198507113130202"},{"doi-asserted-by":"publisher","unstructured":"160. REEVE, E. Feasibility of a Patient-Centered Deprescribing Process to Reduce Inappropriate Use of Proton Pump Inhibitors. The Annals of Pharmacotherapy, Thousand Oaks, v. 9, n. 1, p. 29-38, Jan. 2015.","key":"ref159","DOI":"10.1177\/1060028014558290"},{"unstructured":"161. REY, L. Dicion\u00e1rio de termos t\u00e9cnicos de medicina e sa\u00fade. 2. ed. Rio de Janeiro: Guanabara Koogan, 2012. 1008 p.","key":"ref160"},{"unstructured":"162. RICHTER, J. E. Gastroesophageal Reflux Disease. In: YAMADA, T. et al. Textbook of Gastroenterology. 4th ed. Philadelphia: Lippincott: Williams & Williams, 2003. p. 1196-1224.","key":"ref161"},{"doi-asserted-by":"publisher","unstructured":"163. RICHTER, J. E. The management of heartburn in pregnancy. Alimentary Pharmacology and Therapeutics, Oxford, v. 22, n. 9, p. 749-757, Nov. 2005.","key":"ref162","DOI":"10.1111\/j.1365-2036.2005.02654.x"},{"doi-asserted-by":"publisher","unstructured":"164. ROMANO, C. et al. Functional Dyspepsia: An Enigma in a Conundrum. Journal of Pediatric Gastroenterology and Nutrition, Philadelphia, v. 63, n. 6, p. 579-584, Dec. 2016.","key":"ref163","DOI":"10.1097\/MPG.0000000000001344"},{"unstructured":"165. RUTTER, P. Community Pharmacy - Symptoms, Diagnosis and Treatment. London: Churchill Livingstone, 2004.","key":"ref164"},{"doi-asserted-by":"publisher","unstructured":"166. SAMPATHKUMAR, K. et al. Acute interstitial nephritis due to proton pump inhibitors. Indian Journal of Nephrology, Mumbai, v. 23, n. 4, p. 304-307, July\/Aug. 2013.","key":"ref165","DOI":"10.4103\/0971-4065.114487"},{"doi-asserted-by":"publisher","unstructured":"167. SANTOS, T. R. A. et al. Consumo de medicamentos por idosos, Goi\u00e2nia, Brasil. Revista de Sa\u00fade P\u00fablica, S\u00e3o Paulo, v. 47, n. 1, p. 94-103, 2013. Dispon\u00edvel em: <http:\/\/www.scielo.br\/pdf\/rsp\/v47n1\/13.pdf>. Acesso em: 11 jun. 2019.","key":"ref166","DOI":"10.1590\/S0034-89102013000100013"},{"doi-asserted-by":"publisher","unstructured":"168. SANTOS-OLIVEIRA, R.; COLAUD-CUNHA, S.; COLA\u00c7O, W. Revis\u00e3o da Maytenus ilicifolia Mart. ex Reissek, Celastraceae: Contribui\u00e7\u00e3o ao estudo das propriedades farmacol\u00f3gicas. Revista Brasileira de Farmacognosia, Jo\u00e3o Pessoa, v. 19, n. 2b, p. 650-659, abr.\/jun. 2009.","key":"ref167","DOI":"10.1590\/S0102-695X2009000400025"},{"doi-asserted-by":"publisher","unstructured":"169. SARKAR, M.; HENNESSY, S.; YANG, Y. X. Proton-pump inhibitor use and the risk for community-acquired pneumonia. Annals of Internal Medicine, Philadelphia, v. 149, n. 6, p. 391-398, Sep. 2008.","key":"ref168","DOI":"10.7326\/0003-4819-149-6-200809160-00005"},{"doi-asserted-by":"publisher","unstructured":"170. SEBASTI\u00c1N DOMINGO, J. J. Los nuevos criterios de Roma (IV) de los trastornos funcionales digestivos en la pr\u00e1ctica cl\u00ednica. Medicina Cl\u00ednica, Espa\u00f1a, v. 148, n. 10, p. 435-485, May 2017.","key":"ref169","DOI":"10.1016\/j.medcli.2016.12.020"},{"doi-asserted-by":"publisher","unstructured":"171. SILVA, A. L. et al. Utiliza\u00e7\u00e3o de medicamentos por idosos brasileiros, de acordo com a faixa et\u00e1ria: um inqu\u00e9rito postal. Cadernos de Sa\u00fade P\u00fablica, Rio de Janeiro, v. 28, n. 6, p. 1033-1045, jun. 2012. Dispon\u00edvel em: <http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0102-311X2012000600003>. Acesso em: 11 jun. 2019.","key":"ref170","DOI":"10.1590\/S0102-311X2012000600003"},{"doi-asserted-by":"publisher","unstructured":"172. SILVA, F. M. Dispepsia: caracteriza\u00e7\u00e3o e abordagem. Revista de Medicina, S\u00e3o Paulo, v. 87, n. 4, p. 213-223, out.\/dez. 2008.","key":"ref171","DOI":"10.11606\/issn.1679-9836.v87i4p213-223"},{"unstructured":"173. SOCIEDADE BRASILEIRA DE ENDOCRINOLOGIA; SOCIEDADE BRASILEIRA DE CIRURGIA DE CABE\u00c7A E PESCO\u00c7O. Hipoparatireoidismo: diagn\u00f3stico e tratamento. [S.l.]: AMB, 2013. Dispon\u00edvel em: <http:\/\/amb.org.br\/diretrizes\/_DIRETRIZES\/hipoparatireoidismo_diagnostico_e_tratamento\/files\/assets\/common\/downloads\/publication.pdf>. Acesso em: 11 jun. 2019.","key":"ref172"},{"unstructured":"174. SOCIEDADE BRASILEIRA DE MEDICINA DE FAM\u00cdLIA E COMUNIDADE. Explica\u00e7\u00e3o do tesauro. Rio de Janeiro: SBMFC, 2008. Dispon\u00edvel em: <http:\/\/www.sbmfc.org.br\/media\/file\/ciap\/explicacao_tesauro.pdf>. Acesso em: 11 jun. 2019.","key":"ref173"},{"unstructured":"175. SOCIEDADE BRASILEIRA DE ONCOLOGIA CL\u00cdNICA. Estudos sobre o experimento cl\u00ednico. In: SOCIEDADE BRASILEIRA DE ONCOLOGIA CL\u00cdNICA. Leitura Cr\u00edtica de Artigos Cient\u00edficos. S\u00e3o Paulo, 2011. cap. 9. Dispon\u00edvel em: <https:\/\/www.sboc.org.br\/app\/webroot\/leitura-critica\/LEITURA-CRITICA_C9.pdf>. Acesso em: 11 jun. 2019.","key":"ref174"},{"doi-asserted-by":"publisher","unstructured":"176. SOLOMON, M.; REYNOLDS, J. C. Esophageal Reflux Disease and Its Complications. In: PITCHUMONI, C. S.; DHARMARAJAN, T. S. (ed.). Geriatric Gastroenterology. New York, NY: Springer New York, 2012. p. 311-319.","key":"ref175","DOI":"10.1007\/978-1-4419-1623-5_31"},{"doi-asserted-by":"publisher","unstructured":"177. STRAUS, W. L. et al. Do NSAIDs cause dyspepsia? A meta-analysis evaluating alternative dyspepsia definitions. 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The American Journal of Gastroenterology, New York, v. 100, n. 10, p. 2324-2337, Oct. 2005.","key":"ref179","DOI":"10.1111\/j.1572-0241.2005.00225.x"},{"doi-asserted-by":"publisher","unstructured":"181. THAVORN, K.; MAMDANI, M. M.; STRAUS, S. E. Efficacy of turmeric in the treatment of digestive disorders: a systematic review and meta-analysis protocol. Systematic Reviews, London, v. 3, p. 71, June 2014.","key":"ref180","DOI":"10.1186\/2046-4053-3-71"},{"doi-asserted-by":"publisher","unstructured":"182. THOMPSON COON, J.; ERNST, E. Systematic review: herbal medicinal products for non-ulcer dyspepsia. Alimentary Pharmacology & Therapeutics, Oxford, v. 16, n. 10, p. 1689-1699, Oct. 2002.","key":"ref181","DOI":"10.1046\/j.1365-2036.2002.01339.x"},{"unstructured":"183. TORRE, M. T. A. D. L. et al. Consulta de Indicaci\u00f3n Farmac\u00e9utica: actuaci\u00f3n del farmac\u00e9utico en la resoluci\u00f3n de los trastornos leves de salud. [S.l.: s.d], [200-?]. Dispon\u00edvel em: <http:\/\/www.grupoberbes.es\/uploads\/2\/6\/0\/1\/26011151\/__libro_cofano_indicacin.pdf>. Acesso em: 4 out. 2017.","key":"ref182"},{"doi-asserted-by":"crossref","unstructured":"184. TRAN, T.; LOWRY, A. M.; EL-SERAG, H. B. Meta-analysis: the efficacy of over-the-counter gastro-oesophageal reflux disease therapies. Alimentary Pharmacology Therapeutics, Oxford, v. 25, n. 2, p. 143-153, Jan. 2007.","key":"ref183","DOI":"10.1111\/j.1365-2036.2006.03135.x"},{"unstructured":"185. TRUVEN HEALTH ANALITYCS. Antacids. In: SWEETMAN S. (ed.). Martindale: The Complete Drug Reference. Greenwood Village: Thomson MICROMEDEX, 2018c.","key":"ref184"},{"unstructured":"186. TRUVEN HEALTH ANALITYCS. Micromedex\u00ae CareNotes\u00ae. Data base. New York: IBM, 2018a. Dispon\u00edvel em: <https:\/\/micromedex.com\/>. Acesso em: 19 jan. 2018.","key":"ref185"},{"unstructured":"187. TRUVEN HEALTH ANALITYCS. Micromedex\u00ae Drugdex System\u00ae. Data base. New York: IBM, 2018b. Dispon\u00edvel em: < https:\/\/micromedex.com\/>. Acesso em: 10 nov. 2018.","key":"ref186"},{"doi-asserted-by":"publisher","unstructured":"188. TURCO, R. et al. Do Distinct Functional Dyspepsia Subtypes Exist in Children? Journal of Pediatric Gastroenterology and Nutrition, Philadelphia, v. 62, n. 3, p. 387-392, Mar. 2016.","key":"ref187","DOI":"10.1097\/MPG.0000000000000944"},{"doi-asserted-by":"publisher","unstructured":"189. TUUKKANEN, J.; V\u00c4\u00c4N\u00c4NEN, H. K. Omeprazole, a specific inhibitor of H+-K+-ATPase, inhibits bone resorption in vitro. Calcified Tissue International, New York, v. 38, n. 2, p. 123-125, Feb. 1986.","key":"ref188","DOI":"10.1007\/BF02556841"},{"unstructured":"190. U.S. NATIONAL LIBRARY OF MEDICINE. Medical Subject Headings: MeSH Descriptor Data. Bethesda: NLM, 2018. Dispon\u00edvel em: <https:\/\/www.ncbi.nlm.nih.gov\/mesh>. Acesso em: 10 nov. 2018.","key":"ref189"},{"unstructured":"191. VAKIL, N. B. Antiulcer medications: Mechanism of action, pharmacology, and side effects. Last updated: May 22, 2018. In: POST, T. W. (ed.). UpToDate. Data base. Waltham, MA: UpToDate, 2018.","key":"ref190"},{"doi-asserted-by":"publisher","unstructured":"192. VAN NIEUWENHOVEN, M. A.; BROUNS, F.; BRUMMER, R. J. The effect of physical exercise on parameters of gastrointestinal function. Journal of Neurogastroenterology and Motility, Osney Mead, v. 11, n. 6, p. 431-439, Dec. 1999.","key":"ref191","DOI":"10.1046\/j.1365-2982.1999.00169.x"},{"doi-asserted-by":"publisher","unstructured":"193. VAN WIJK, M. P. et al. Effect of body position changes on postprandial gastroesophageal reflux and gastric emptying in the healthy premature neonate. The Journal of Pediatrics, St. Louis, v. 151, n. 6, p. 585-590, 590.e1-2, Dec. 2007.","key":"ref192","DOI":"10.1016\/j.jpeds.2007.06.015"},{"unstructured":"194. VAZQUEZ, J. C. Heartburn in pregnancy. BMJ Clinical Evidence, London, p. 1411, Sep. 2015. Dispon\u00edvel em: <https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4562453\/>. Acesso em: 11 jun. 2019.","key":"ref193"},{"doi-asserted-by":"publisher","unstructured":"195. WALLACE, J. L. How do NSAIDs cause ulcer disease? Best Practice & Research. Clinical Gastroenterology, London, v. 14, n. 1, p. 147-159, Feb. 2000.","key":"ref194","DOI":"10.1053\/bega.1999.0065"},{"unstructured":"196. WINTER, H. S. Patient education: Acid reflux (gastroesophageal reflux disease) in children and adolescents (Beyond the Basics). Last updated: Jul. 2018. In: POST, T. W. (ed.). UpToDate. Data base. Waltham, MA: UpToDate, 2018.","key":"ref195"},{"doi-asserted-by":"publisher","unstructured":"197. WOLFE, M. M.; SACHS, G. Acid suppression: optimizing therapy for gastroduodenal ulcer healing, gastroesophageal reflux disease, and stress-related erosive syndrome. Gastroenterology, Philadelphia, v. 118, n. 2, p. S9-31. Feb. 2000. Supl. 1.","key":"ref196","DOI":"10.1016\/S0016-5085(00)70004-7"},{"unstructured":"198. WORLD GASTROENTEROLOGY ORGANISATION PRACTICE GUIDELINES. Manejo dos sintomas comuns de doen\u00e7as gastrointestinais na comunidade: perspectiva mundial sobre azia, constipa\u00e7\u00e3o, distens\u00e3o e dor\/desconforto abdominal. [S.l.]: WGO, 2013. Dispon\u00edvel em: <http:\/\/www.worldgastroenterology.org\/UserFiles\/file\/guidelines\/common-gi-symptoms-portuguese-2013.pdf>. Acesso em: 11 jun. 2019.","key":"ref197"},{"unstructured":"199. WORLD HEALTH ORGANIZATION. Department of Child and Adolescent Health and Development. Breastfeeding and Maternal Medication: Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs. Geneva, 2002. Dispon\u00edvel em: <http:\/\/apps.who.int\/iris\/bitstream\/10665\/62435\/1\/55732.pdf>. Acesso em: 11 jun. 2019.","key":"ref198"},{"doi-asserted-by":"publisher","unstructured":"200. XIE, Y. et al. Risk of death among users of Proton Pump Inhibitors: a longitudinal observational cohort study of United States veterans. BMJ open, London, v. 7, n. 6, p. e015735, July 2017.","key":"ref199","DOI":"10.1136\/bmjopen-2016-015735"},{"doi-asserted-by":"publisher","unstructured":"201. YAMASAKI, T.; FASS, R. Reflux Hypersensitivity: A New Functional Esophageal Disorder. Journal of Neurogastroenterology and Motility, Seoul, v. 23, n. 4, p. 495-503, Oct. 2017.","key":"ref200","DOI":"10.5056\/jnm17097"},{"doi-asserted-by":"publisher","unstructured":"202. ZHOU, W.; SU, J.; ZHANG, H. Efficacy and Safety of Acupuncture for the Treatment of Functional Dyspepsia: Meta-Analysis. Journal of Alternative and Complementary Medicine, Ney York, v. 22, n. 5, p. 380-389. 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