{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T21:56:48Z","timestamp":1765231008470,"version":"3.28.0"},"reference-count":12,"publisher":"Texas Heart Institute Journal","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,4]]},"abstract":"<jats:p>\n          <jats:italic>Neisseria elongata<\/jats:italic>, a common oral bacterium, has been recognized as a cause of infections such as infective endocarditis, septicemia, and osteomyelitis. <jats:italic>Neisseria<\/jats:italic>-induced infective endocarditis, although infrequently reported, typically arises after dental procedures. Without antibiotic therapy, its complications can be severe.<\/jats:p>\n        <jats:p>We report the case of a 27-year-old man who presented with fever, severe dyspnea, and a leg abscess from cellulitis. An echocardiogram showed a vegetation-like echogenic structure on the septal leaflet of the patient's native tricuspid valve, and an insignificant Gerbode defect. Three blood cultures grew gram-negative, antibiotic-susceptible coccobacilli that were confirmed to be <jats:italic>N. elongata<\/jats:italic>. Subsequent DNA sequencing conclusively isolated <jats:italic>N. elongata<\/jats:italic> subsp <jats:italic>nitroreducens<\/jats:italic> as the organism responsible for the infective endocarditis. The patient recovered after 21 days of antibiotic therapy. In addition to the patient's unusual case, we discuss the nature and isolation of <jats:italic>N. elongata<\/jats:italic> and its subspecies.<\/jats:p>","DOI":"10.14503\/thij-13-3153","type":"journal-article","created":{"date-parts":[[2014,4,1]],"date-time":"2014-04-01T16:43:24Z","timestamp":1396370604000},"page":"227-230","source":"Crossref","is-referenced-by-count":7,"title":["Infective Endocarditis Caused by Neisseria elongata on a Native Tricuspid Valve and Confirmed by DNA Sequencing"],"prefix":"10.14503","volume":"41","author":[{"given":"Yeon Pyo","family":"Yoo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ki-Woon","family":"Kang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyeon Soo","family":"Yoon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seungmin","family":"Yoo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Myung-Shin","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5628","reference":[{"issue":"3","key":"i0730-2347-41-2-227-b1","series-title":"J Clin Microbiol","first-page":"719","article-title":"Association of an important Neisseria species, Neisseria elongata subsp. nitroreducens, with bacteremia, endocarditis, and osteomyelitis","volume":"30","year":"1992","unstructured":"Wong\n              JD\n            , JandaJM.\n          Association of an important Neisseria species, Neisseria elongata subsp. nitroreducens, with bacteremia, endocarditis, and osteomyelitis. J Clin Microbiol1992; 30(3):719\u201320."},{"issue":"4","key":"i0730-2347-41-2-227-b2","series-title":"Diagn Microbiol Infect Dis","first-page":"265","article-title":"Neisseria elongata subsp. elongata, as a cause of human endocarditis","volume":"39","year":"2001","unstructured":"Apisarnthanarak\n              A\n            , DunaganWC, DunneWM.\n          Neisseria elongata subsp. elongata, as a cause of human endocarditis. Diagn Microbiol Infect Dis2001;39(4):265\u20136."},{"issue":"2","key":"i0730-2347-41-2-227-b3","series-title":"Eur J Clin Microbiol Infect Dis","first-page":"106","article-title":"Tricuspid valve endocarditis due to Neisseria cinerea","volume":"22","year":"2003","unstructured":"Benes\n              J\n            , DzupovaO, KrizovaP, RozsypalH.\n          Tricuspid valve endocarditis due to Neisseria cinerea. Eur J Clin Microbiol Infect Dis2003;22(2):106\u20137."},{"issue":"5","key":"i0730-2347-41-2-227-b4","series-title":"Clin Microbiol Infect","first-page":"426","article-title":"Neisseria elongata endocarditis: case report and literature review","volume":"9","year":"2003","unstructured":"Haddow\n              LJ\n            , MulgrewC, AnsariA, MiellJ, JacksonG, MalnickH, RaoGG.\n          Neisseria elongata endocarditis: case report and literature review. Clin Microbiol Infect2003;9(5):426\u201330."},{"issue":"Pt 3","key":"i0730-2347-41-2-227-b5","series-title":"J Med Microbiol","first-page":"376","article-title":"Neisseria elongata endocarditis complicated by brain embolism and abscess","volume":"57","year":"2008","unstructured":"Hsiao\n              JF\n            , LeeMH, ChiaJH, HoWJ, ChuJJ, ChuPH.\n          Neisseria elongata endocarditis complicated by brain embolism and abscess. J Med Microbiol2008;57(Pt 3):376\u201381."},{"issue":"8","key":"i0730-2347-41-2-227-b6","series-title":"Echocardiography","first-page":"993","article-title":"The Gerbode defect: left ventricular to right atrial communication-anatomic, hemodynamic, and echocardiographic features","volume":"26","year":"2009","unstructured":"Silbiger\n              JJ\n            , KamranM, HandwerkerS, KumarN, MarcaliM.\n          The Gerbode defect: left ventricular to right atrial communication-anatomic, hemodynamic, and echocardiographic features. Echocardiography2009;26(8):993\u20138."},{"issue":"1","key":"i0730-2347-41-2-227-b7","series-title":"J Gen Microbiol","first-page":"67","article-title":"Neisseria elongata sp.nov., a rod-shaped member of the genus Neisseria. Re-evaluation of cell shape as a criterion in classification","volume":"60","year":"1970","unstructured":"Bovre\n              K\n            , HoltenE.\n          Neisseria elongata sp.nov., a rod-shaped member of the genus Neisseria. Re-evaluation of cell shape as a criterion in classification. J Gen Microbiol1970;60(1):67\u201375."},{"issue":"9","key":"i0730-2347-41-2-227-b8","series-title":"Enferm Infecc Microbiol Clin","first-page":"556","article-title":"Endocarditis due to the Neisseria elongata subspecies nitroreducens [in Spanish]","volume":"22","year":"2004","unstructured":"Cervera\n              JI\n            , TodoliJA, SauquilloJM, CalabuigE.\n          Endocarditis due to the Neisseria elongata subspecies nitroreducens [in Spanish]. Enferm Infecc Microbiol Clin2004;22(9):556\u20137."},{"issue":"8","key":"i0730-2347-41-2-227-b9","series-title":"Eur J Clin Microbiol Infect Dis","first-page":"625","article-title":"Endocarditis caused by Neisseria elongata subspecies nitroreducens: case report and literature review","volume":"12","year":"1993","unstructured":"Struillou\n              L\n            , RaffiF, BarrierJH.\n          Endocarditis caused by Neisseria elongata subspecies nitroreducens: case report and literature review. Eur J Clin Microbiol Infect Dis1993;12(8):625\u20137."},{"issue":"6","key":"i0730-2347-41-2-227-b10","series-title":"Clin Infect Dis","first-page":"1471","article-title":"Endocarditis due to Neisseria elongata subspecies nitroreducens: case report and review","volume":"26","year":"1998","unstructured":"Dominguez\n              EA\n            , SmithTL.\n          Endocarditis due to Neisseria elongata subspecies nitroreducens: case report and review. Clin Infect Dis1998;26(6):1471\u20133."},{"issue":"2","key":"i0730-2347-41-2-227-b11","series-title":"J Clin Microbiol","first-page":"886","article-title":"Endocarditis due to a new rod-shaped Neisseria sp","volume":"43","year":"2005","unstructured":"Michaux-Charachon\n              S\n            , LavigneJP, Le FlecheA, BouzigesN, SottoA, GrimontPA.\n          Endocarditis due to a new rod-shaped Neisseria sp. J Clin Microbiol2005;43(2):886\u20139."},{"issue":"4","key":"i0730-2347-41-2-227-b12","series-title":"Pediatr Infect Dis J","first-page":"391","article-title":"Neisseria elongata subsp. nitroreducens endocarditis in a seven-year-old boy","volume":"24","year":"2005","unstructured":"Hoshino\n              T\n            , OhkusuK, SudoF, NakajimaH, IshiwadaN, EzakiT, KohnoY.\n          Neisseria elongata subsp. nitroreducens endocarditis in a seven-year-old boy. 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