{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T19:02:28Z","timestamp":1761418948572,"version":"3.28.0"},"reference-count":29,"publisher":"Texas Heart Institute Journal","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,10]]},"abstract":"<jats:p>Essential thrombocythemia is a rare type of myeloproliferative disorder. Cerebral, myocardial, and peripheral thrombosis are all frequent complications of the disease.<\/jats:p>\n        <jats:p>A 71-year-old man presented with severe coronary artery disease, associated with cerebral vascular ischemic changes and erythromelalgia. His platelet count was 1,486 \u00d710<jats:sup>3<\/jats:sup>\/\u03bcL. The patient underwent successful myocardial revascularization by means of an off-pump technique after his platelet count had been reduced by hydroxycarbamide administration.<\/jats:p>\n        <jats:p>We conclude that the use of off-pump cardiopulmonary bypass in high-risk patients with essential thrombocythemia is safe. Reducing platelet count via the administration of hydroxycarbamide and the careful balancing of antiplatelets and anticoagulants is crucial in determining the outcome of surgery.<\/jats:p>","DOI":"10.14503\/thij-13-3508","type":"journal-article","created":{"date-parts":[[2014,10,1]],"date-time":"2014-10-01T20:04:57Z","timestamp":1412193897000},"page":"537-542","source":"Crossref","is-referenced-by-count":7,"title":["Off-Pump Myocardial Revascularization in a High-Risk Patient with Essential Thrombocythemia"],"prefix":"10.14503","volume":"41","author":[{"given":"Ahmad K.","family":"Darwazah","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamad","family":"Madi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rami","family":"Zagha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yahia","family":"Hawash","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5628","reference":[{"issue":"2","key":"i0730-2347-41-5-537-b1","series-title":"Am Heart J","first-page":"573","article-title":"Thrombocythemia and coronary artery disease","volume":"122","year":"1991","unstructured":"Scheffer\n              MG\n            , MichielsJJ, SimoonsML, RoelandtJR.\n          Thrombocythemia and coronary artery disease. 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Curr Hematol Rep2003;2(3):248\u201356."},{"issue":"1","key":"i0730-2347-41-5-537-b8","series-title":"N Engl J Med","first-page":"33","article-title":"Hydroxyurea compared with anagrelide in high-risk essential thrombocythemia","volume":"353","year":"2005","unstructured":"Harrison\n              CN\n            , CampbellPJ, BuckG, WheatleyK, EastCL, BarefordD, et al. Hydroxyurea compared with anagrelide in high-risk essential thrombocythemia. N Engl J Med2005; 353(1):33\u201345."},{"issue":"1","key":"i0730-2347-41-5-537-b9","series-title":"Ann Thorac Surg","first-page":"e5","article-title":"Thrombocytapheresis: managing essential thrombocythemia in a surgical patient","volume":"92","year":"2011","unstructured":"Das\n              SS\n            , BoseS, ChatterjeeS, ParidaAK, PradhanSK.\n          Thrombocytapheresis: managing essential thrombocythemia in a surgical patient. 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Neth Heart J2010;18(7\u20138): 378\u201380."},{"issue":"8","key":"i0730-2347-41-5-537-b14","series-title":"Jpn J Thorac Cardiovasc Surg","first-page":"767","article-title":"A case of coronary artery bypass surgery using left internal thoracic artery and right gastroepiploic artery for a patient with essential thrombocythemia [in Japanese]","volume":"46","year":"1998","unstructured":"Ohto\n              T\n            , ShiharaH, MiyauchiY, NakajimaN.\n          A case of coronary artery bypass surgery using left internal thoracic artery and right gastroepiploic artery for a patient with essential thrombocythemia [in Japanese]. Jpn J Thorac Cardiovasc Surg1998;46(8):767\u201371."},{"issue":"2","key":"i0730-2347-41-5-537-b15","series-title":"Am Heart J","first-page":"406","article-title":"Acute myocardial infarction with essential thrombocythemia in a young man","volume":"106","year":"1983","unstructured":"Pick\n              RA\n            , GloverMU, NanfroJJ, DubbsWF, GibbonsJA, ViewegWV.\n          Acute myocardial infarction with essential thrombocythemia in a young man. Am Heart J1983;106(2): 406\u20137."},{"issue":"4","key":"i0730-2347-41-5-537-b16","series-title":"Chest","first-page":"1162","article-title":"Essential thrombocythemia associated with angina pectoris with unusual coronary artery findings","volume":"100","year":"1991","unstructured":"Yoshida\n              H\n            , HoshinoT, IshidaT, ShiomuraT, KaburagiT.\n          Essential thrombocythemia associated with angina pectoris with unusual coronary artery findings. Chest1991;100(4): 1162\u20133."},{"issue":"8","key":"i0730-2347-41-5-537-b17","series-title":"Nihon Kyobu Geka Gakkai Zasshi","first-page":"1237","article-title":"A case report: coronary artery bypass grafting for the patient with essential thrombocythemia [in Japanese]","volume":"39","year":"1991","unstructured":"Iemura\n              J\n            , SatoT, YamadaT, AndoF.\n          A case report: coronary artery bypass grafting for the patient with essential thrombocythemia [in Japanese]. Nihon Kyobu Geka Gakkai Zasshi1991;39(8):1237\u201341."},{"issue":"5","key":"i0730-2347-41-5-537-b18","series-title":"J Cardiothorac Vasc Anesth","first-page":"552","article-title":"Essential thrombocythemia and coronary artery bypass surgery","volume":"8","year":"1994","unstructured":"Schott\n              U.\n            \n          \n          Essential thrombocythemia and coronary artery bypass surgery. 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Cardiovasc Pathol2003;12(4):216\u20138."},{"issue":"3","key":"i0730-2347-41-5-537-b21","series-title":"J Thromb Thrombolysis","first-page":"165","article-title":"Left main coronary thrombosis with essential thrombocythemia","volume":"22","year":"2006","unstructured":"Nurkalem\n              Z\n            , UsluN, GorguluS, ErenM.\n          Left main coronary thrombosis with essential thrombocythemia. J Thromb Thrombolysis2006;22(3):165\u20137."},{"issue":"4","key":"i0730-2347-41-5-537-b22","series-title":"Anadolu Kardiyol Derg","first-page":"444","article-title":"Coronary bypass surgery in essential thrombocythemia","volume":"7","year":"2007","unstructured":"Yorukoglu\n              Y\n            , AyliM, AkgulE.\n          Coronary bypass surgery in essential thrombocythemia. Anadolu Kardiyol Derg2007;7 (4):444\u20135."},{"key":"i0730-2347-41-5-537-b23","series-title":"J Cardiothorac Surg","first-page":"5","article-title":"Aortic valve replacement in a young patient with essential thrombocytosis","volume":"3","year":"2008","unstructured":"Ahmed\n              K\n            , VohraHA, MilneA, LangleySM.\n          Aortic valve replacement in a young patient with essential thrombocytosis. J Cardiothorac Surg2008;3:5."},{"issue":"20","key":"i0730-2347-41-5-537-b24","series-title":"Eur Heart J","first-page":"2492","article-title":"Early graft patency after off-pump and on-pump coronary bypass surgery: a prospective randomized study","volume":"31","year":"2010","unstructured":"Sousa Uva\n              M\n            , CavacoS, OliveiraAG, MatiasF, SilvaC, MesquitaA, et al. Early graft patency after off-pump and on-pump coronary bypass surgery: a prospective randomized study. Eur Heart J2010;31(20):2492\u20139."},{"issue":"2","key":"i0730-2347-41-5-537-b25","series-title":"J Thorac Cardiovasc Surg","first-page":"290","article-title":"Activation of the coagulation system during coronary artery bypass grafting: comparison between on-pump and off-pump techniques","volume":"131","year":"2006","unstructured":"Paparella\n              D\n            , GaleoneA, VenneriMT, CovielloM, ScrasciaG, MarraudinoN, et al. Activation of the coagulation system during coronary artery bypass grafting: comparison between on-pump and off-pump techniques. J Thorac Cardiovasc Surg2006;131(2):290\u20137."},{"issue":"19","key":"i0730-2347-41-5-537-b26","series-title":"N Engl J Med","first-page":"1827","article-title":"On-pump versus off-pump coronary-artery bypass surgery","volume":"361","year":"2009","unstructured":"Shroyer\n              AL\n            , GroverFL, HattlerB, CollinsJF, McDonaldGO, KozoraE, et al. On-pump versus off-pump coronary-artery bypass surgery. 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N Engl J Med2003;348(5):394\u2013402."},{"issue":"15","key":"i0730-2347-41-5-537-b29","series-title":"JAMA","first-page":"1841","article-title":"Off-pump vs conventional coronary artery bypass grafting: early and 1-year graft patency, cost, and quality-of-life outcomes: a randomized trial","volume":"291","year":"2004","unstructured":"Puskas\n              JD\n            , WilliamsWH, MahoneyEM, HuberPR, BlockPC, DukePG, et al. Off-pump vs conventional coronary artery bypass grafting: early and 1-year graft patency, cost, and quality-of-life outcomes: a randomized trial. JAMA2004;291 (15):1841\u20139."}],"container-title":["Texas Heart Institute Journal"],"original-title":[],"link":[{"URL":"https:\/\/thij.kglmeridian.com\/view\/journals\/thij\/41\/5\/article-p537.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/meridian.allenpress.com\/thij\/article-pdf\/41\/5\/537\/2549903\/thij-13-3508.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thij.kglmeridian.com\/downloadpdf\/journals\/thij\/41\/5\/article-p537.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thij.kglmeridian.com\/downloadpdf\/journals\/thij\/41\/5\/article-p537.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,7]],"date-time":"2024-11-07T15:29:46Z","timestamp":1730993386000},"score":1,"resource":{"primary":{"URL":"https:\/\/thij.kglmeridian.com\/view\/journals\/thij\/41\/5\/article-p537.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10]]},"references-count":29,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.14503\/thij-13-3508","relation":{},"ISSN":["0730-2347","1526-6702"],"issn-type":[{"type":"print","value":"0730-2347"},{"type":"electronic","value":"1526-6702"}],"subject":[],"published":{"date-parts":[[2014,10]]}}}