{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,25]],"date-time":"2026-10-25T05:27:07Z","timestamp":1792906027085,"version":"4.5.0"},"reference-count":32,"publisher":"Texas Heart Institute Journal","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:p>Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) is a rare congenital condition. It responds well to early diagnosis and treatment, but otherwise the prognosis is poor. We present our case series of 12 patients (mean age, 2 \u00b1 2.58 yr; age range, 2 mo\u20138 yr), emphasizing the diagnostic process and discussing our surgical results. The diagnosis of ALCAPA should be suspected in infants who have dilated cardiomyopathy with electrocardiographic changes that suggest ischemia, and in older children who have isolated mitral regurgitation. When clinical suspicion is high, the results of 2-dimensional echocardiography combined with color-flow Doppler studies in expert hands can establish the diagnosis, thus avoiding angiography in critically ill infants. The treatment of choice in our patients was transfer and reimplantation of the left coronary artery onto the ascending aorta. There were 2 deaths: both were infants in extremis who underwent emergency surgery. An older child with severe ventricular dysfunction was given mechanical ventricular assistance and then heart transplantation. As of this report, all 10 survivors remained well and asymptomatic.<\/jats:p>","DOI":"10.14503\/thij-13-3849","type":"journal-article","created":{"date-parts":[[2015,8,3]],"date-time":"2015-08-03T13:22:06Z","timestamp":1438608126000},"page":"350-356","source":"Crossref","is-referenced-by-count":21,"title":["Anomalous Origin of the Left Coronary Artery from the Pulmonary Artery: Diagnoses and Surgical Results in 12 Pediatric Patients"],"prefix":"10.14503","volume":"42","author":[{"given":"Moises","family":"Rodriguez-Gonzalez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio Moruno","family":"Tirado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reza","family":"Hosseinpour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose Santos","family":"de Soto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5628","reference":[{"issue":"2","key":"i0730-2347-42-4-350-b1","series-title":"Centr Eur J Med","first-page":"140","article-title":"Coronary artery anomalies - a short review","volume":"2","year":"2007","unstructured":"Zemanek\n              D, \n            \n              Veselka\n              J.\n            \n          \n          Coronary artery anomalies - a short review. 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Zhongguo Dang Dai Er Ke Za Zhi2007;9(1):25\u20137."},{"issue":"2","key":"i0730-2347-42-4-350-b4","series-title":"Ir J Med Sci","first-page":"127","article-title":"A review of 15-year experience with anomalous origin of the left coronary artery","volume":"177","year":"2008","unstructured":"Walsh\n              MA, \n            \n              Duff\n              D, \n            \n              Oslizlok\n              P, \n            \n              Redmond\n              M, \n            \n              Walsh\n              KP, \n            \n              Wood\n              AE, \n            \n              Coleman\n              DM.\n            \n          \n          A review of 15-year experience with anomalous origin of the left coronary artery. 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Acta Cardiol2009;64(6): 835\u20137."},{"issue":"3","key":"i0730-2347-42-4-350-b7","series-title":"Pediatr Cardiol","first-page":"385","article-title":"Asymptomatic anomalous origin of the left coronary artery from the pulmonary artery","volume":"30","year":"2009","unstructured":"Irving\n              C, \n            \n              Wren\n              C.\n            \n          \n          Asymptomatic anomalous origin of the left coronary artery from the pulmonary artery. 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J Invasive Cardiol2008;20(10): 564\u20136."},{"issue":"2","key":"i0730-2347-42-4-350-b9","series-title":"Pediatr Radiol","first-page":"163","article-title":"ALCAPA: the role of myocardial viability studies in determining prognosis","volume":"40","year":"2010","unstructured":"Browne\n              LP, \n            \n              Kearney\n              D, \n            \n              Taylor\n              MD, \n            \n              Chung\n              T, \n            \n              Slesnick\n              TC, \n            \n              Nutting\n              AC, \n            \n              Krishnamurthy\n              R.\n            \n          \n          ALCAPA: the role of myocardial viability studies in determining prognosis. 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Ann Pediatr Cardiol2008;1(1):65\u20137."},{"issue":"Suppl 3","key":"i0730-2347-42-4-350-b13","series-title":"Cardiol Young","first-page":"26","article-title":"Echocardiographic imaging of anomalous origin of the coronary arteries","volume":"20","year":"2010","unstructured":"Cohen\n              MS, \n            \n              Herlong\n              RJ, \n            \n              Silverman\n              NH.\n            \n          \n          Echocardiographic imaging of anomalous origin of the coronary arteries. 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