{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T08:04:20Z","timestamp":1772179460193,"version":"3.50.1"},"reference-count":33,"publisher":"Texas Heart Institute Journal","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:p>We tested the hypothesis that later completion of the Fontan procedure is associated with improved exercise capacity in the current period of staged single-ventricle palliation. We performed a retrospective study, in Fontan patients, of exercise stress test data from April 2003 through March 2011. Patients were included if they had received staged palliations in accordance with current surgical strategy, defined as the performance of a superior cavopulmonary connection at \u22641 year of age, followed in subsequent years by Fontan completion. Patients with a pacemaker or respiratory exchange ratio &lt;1 were excluded. Early and late Fontan groups were created on the basis of whether Fontan completion had been performed at &lt;4 or \u2265 4 years of age. The primary predictor variable was age at Fontan completion, and the primary marker of exercise performance was the percentage of predicted maximum oxygen consumption. During the study period, 55 patients were identified (mean age, 11.7 \u00b1 2.8 yr).<\/jats:p>\n        <jats:p>Older age at Fontan completion correlated positively with higher percentages of predicted maximum oxygen consumption (R=0.286, P=0.034). Patients in whom Fontan completion was performed at \u22654 years of age had higher percentages of predicted maximum oxygen consumption than did those in whom completion was at &lt;4 years of age (84.4 \u00b1 21.5 vs 72.9 \u00b1 18.1; P=0.041). Later Fontan completion might be associated with improved exercise capacity in patients palliated in accordance with contemporary surgical strategy.<\/jats:p>","DOI":"10.14503\/thij-14-4178","type":"journal-article","created":{"date-parts":[[2015,8,3]],"date-time":"2015-08-03T13:22:06Z","timestamp":1438608126000},"page":"333-340","source":"Crossref","is-referenced-by-count":20,"title":["Older Age at Completion of Fontan Procedure Is Associated with Improved Percentage of Predicted Maximum Oxygen Uptake"],"prefix":"10.14503","volume":"42","author":[{"given":"Elijah H.","family":"Bolin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiraz A.","family":"Maskatia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda L.","family":"Tate","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher J.","family":"Petit","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5628","reference":[{"issue":"7","key":"i0730-2347-42-4-333-b1","series-title":"J Am Coll Cardiol","first-page":"1967","article-title":"Influence of ventricular morphology on aerobic exercise capacity in patients after the Fontan operation","volume":"37","year":"2001","unstructured":"Ohuchi\n              H, \n            \n              Yasuda\n              K, \n            \n              Hasegawa\n              S, \n            \n              Miyazaki\n              A, \n            \n              Takamuro\n              M, \n            \n              Yamada\n              O, \n          \n          et al. 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Ann Thorac Surg2008;85(3):818\u201321."},{"issue":"2","key":"i0730-2347-42-4-333-b3","series-title":"J Am Coll Cardiol","first-page":"85","article-title":"Contemporary outcomes after the Fontan procedure: a Pediatric Heart Network multicenter study","volume":"52","year":"2008","unstructured":"Anderson\n              PA, \n            \n              Sleeper\n              LA, \n            \n              Mahony\n              L, \n            \n              Colan\n              SD, \n            \n              Atz\n              AM, \n            \n              Breitbart\n              RE, \n          \n          et al. Contemporary outcomes after the Fontan procedure: a Pediatric Heart Network multicenter study. 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Heart1997;78(2):154\u20139."},{"issue":"18","key":"i0730-2347-42-4-333-b11","series-title":"Circulation","first-page":"1775","article-title":"Peripheral vascular adaptation and orthostatic tolerance in Fontan physiology","volume":"120","year":"2009","unstructured":"Krishnan\n              US, \n            \n              Taneja\n              I, \n            \n              Gewitz\n              M, \n            \n              Young\n              R, \n            \n              Stewart\n              J.\n            \n          \n          Peripheral vascular adaptation and orthostatic tolerance in Fontan physiology. Circulation2009;120(18):1775\u201383."},{"issue":"3","key":"i0730-2347-42-4-333-b12","series-title":"J Thorac Cardiovasc Surg","first-page":"436","article-title":"Subdiaphragmatic venous hemodynamics in the Fontan circulation","volume":"121","year":"2001","unstructured":"Hsia\n              TY, \n            \n              Khambadkone\n              S, \n            \n              Deanfield\n              JE, \n            \n              Taylor\n              JF, \n            \n              Migliavacca\n              F, \n            \n              De Leval\n              MR.\n            \n          \n          Subdiaphragmatic venous hemodynamics in the Fontan circulation. J Thorac Cardiovasc Surg2001;121(3):436\u201347."},{"issue":"3","key":"i0730-2347-42-4-333-b13","series-title":"Interact Cardiovasc Thorac Surg","first-page":"428","article-title":"The Fontan circulation: who controls cardiac output?","volume":"10","year":"2010","unstructured":"Gewillig\n              M, \n            \n              Brown\n              SC, \n            \n              Eyskens\n              B, \n            \n              Heying\n              R, \n            \n              Ganame\n              J, \n            \n              Budts\n              W, \n          \n          et al. The Fontan circulation: who controls cardiac output?Interact Cardiovasc Thorac Surg2010;10(3):428\u201333."},{"issue":"6","key":"i0730-2347-42-4-333-b14","series-title":"J Am Coll Cardiol","first-page":"1424","article-title":"Exercise responses in patients with congenital heart disease after Fontan repair: patterns and determinants of performance","volume":"15","year":"1990","unstructured":"Gewillig\n              MH, \n            \n              Lundstrom\n              UR, \n            \n              Bull\n              C, \n            \n              Wyse\n              RK, \n            \n              Deanfield\n              JE.\n            \n          \n          Exercise responses in patients with congenital heart disease after Fontan repair: patterns and determinants of performance. 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Pediatr Cardiol1997;18(5):357\u201360."},{"issue":"4","key":"i0730-2347-42-4-333-b16","series-title":"J Am Coll Cardiol","first-page":"785","article-title":"Cardiorespiratory response to exercise after modified Fontan operation: determinants of performance","volume":"29","year":"1997","unstructured":"Durongpisitkul\n              K, \n            \n              Driscoll\n              DJ, \n            \n              Mahoney\n              DW, \n            \n              Wollan\n              PC, \n            \n              Mottram\n              CD, \n            \n              Puga\n              FJ, \n            \n              Danielson\n              GK.\n            \n          \n          Cardiorespiratory response to exercise after modified Fontan operation: determinants of performance. 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