{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T12:43:36Z","timestamp":1756385016060,"version":"3.28.0"},"reference-count":16,"publisher":"Texas Heart Institute Journal","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:p>ST-segment-elevation myocardial infarction is a leading cause of cardiovascular morbidity and death. We describe the case of a 51-year-old woman with advanced adenocarcinoma of the lung who presented with ST-segment elevation in the presence of an extracardiac lung mass but no objective evidence of myocardial ischemia or pericardial involvement. After the patient died of hypoxic respiratory failure, autopsy findings confirmed normal-appearing pericardium and myocardium, and mild-to-moderate atherosclerosis in the coronary arteries. A 4.5 \u00d7 4-cm extracardiac left hilar lung mass was confirmed to be poorly differentiated adenocarcinoma of the lung adjacent to the myocardium. The persistent current of injury that had been detected electrocardiographically was thought to occur from direct myocardial compression. ST-segment elevations secondary to direct mass contact on the myocardium should be considered in patients who have a malignancy and ST-segment elevation.<\/jats:p>","DOI":"10.14503\/thij-14-4268","type":"journal-article","created":{"date-parts":[[2015,8,3]],"date-time":"2015-08-03T13:22:06Z","timestamp":1438608126000},"page":"381-384","source":"Crossref","is-referenced-by-count":4,"title":["Noninfiltrating Adenocarcinoma of the Lung Causing ST-Segment Elevation"],"prefix":"10.14503","volume":"42","author":[{"given":"Shenil","family":"Shah","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bimal","family":"Padaliya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sri Krishna Madan","family":"Mohan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5628","reference":[{"issue":"25","key":"i0730-2347-42-4-381-b1","series-title":"Circulation","first-page":"3137","article-title":"Trends and disparities in coronary heart disease, stroke, and other cardiovascular diseases in the United States: findings of the national conference on cardiovascular disease prevention","volume":"102","year":"2000","unstructured":"Cooper\n              R, \n            \n              Cutler\n              J, \n            \n              Desvigne-Nickens\n              P, \n            \n              Fortmann\n              SP, \n            \n              Friedman\n              L, \n            \n              Havlik\n              R, \n          \n          et al. Trends and disparities in coronary heart disease, stroke, and other cardiovascular diseases in the United States: findings of the national conference on cardiovascular disease prevention. Circulation2000;102(25):3137\u201347."},{"issue":"16","key":"i0730-2347-42-4-381-b2","series-title":"J Am Coll Cardiol","first-page":"1581","article-title":"Third universal definition of myocardial infarction","volume":"60","year":"2012","unstructured":"Thygesen\n              K, \n            \n              Alpert\n              JS, \n            \n              Jaffe\n              AS, \n            \n              Simoons\n              ML, \n            \n              Chaitman\n              BR, \n            \n              White\n              HD, \n          \n          et al. Third universal definition of myocardial infarction. J Am Coll Cardiol2012;60(16):1581\u201398."},{"issue":"4","key":"i0730-2347-42-4-381-b3","series-title":"Circulation","first-page":"e362","article-title":"2013 ACCF\/AHA guideline for the management of ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation\/American Heart Association Task Force on Practice Guidelines [published erratum appears in Circulation 2013;128(25):e481]","volume":"127","year":"2013","unstructured":"O'Gara\n              PT, \n            \n              Kushner\n              FG, \n            \n              Ascheim\n              DD, \n            \n              Casey\n              DE\n              Jr\n            , ChungMK, de LemosJA, \n          et al. 2013 ACCF\/AHA guideline for the management of ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation\/American Heart Association Task Force on Practice Guidelines [published erratum appears in Circulation 2013;128(25):e481]. Circulation2013;127(4):e362\u2013425."},{"issue":"22","key":"i0730-2347-42-4-381-b4","series-title":"N Engl J Med","first-page":"2128","article-title":"ST-segment elevation in conditions other than acute myocardial infarction","volume":"349","year":"2003","unstructured":"Wang\n              K, \n            \n              Asinger\n              RW, \n            \n              Marriott\n              HJ.\n            \n          \n          ST-segment elevation in conditions other than acute myocardial infarction. N Engl J Med2003;349(22):2128\u201335."},{"issue":"1","key":"i0730-2347-42-4-381-b5","series-title":"Minerva Cardioangiol","first-page":"81","article-title":"Persistent ST-segment elevation in a patient with metastatic involvement of the heart","volume":"49","year":"2001","unstructured":"Astorri\n              E, \n            \n              Fiorina\n              P, \n            \n              Pattoneri\n              P, \n            \n              Paganelli\n              C.\n            \n          \n          Persistent ST-segment elevation in a patient with metastatic involvement of the heart. Minerva Cardioangiol2001;49(1):81\u20135."},{"issue":"4","key":"i0730-2347-42-4-381-b6","series-title":"Ann Nucl Med","first-page":"381","article-title":"A case of double cancers with myocardial metastasis mimicking acute myocardial infarction both on an electrocardiogram and on Tc-99m-MIBI myocardial SPECT","volume":"15","year":"2001","unstructured":"Konishi\n              S, \n            \n              Kojima\n              T, \n            \n              Ichiyanagi\n              K, \n            \n              Kinihiko\n              S, \n            \n              Yokoyama\n              K, \n            \n              Taki\n              J, \n          \n          et al. A case of double cancers with myocardial metastasis mimicking acute myocardial infarction both on an electrocardiogram and on Tc-99m-MIBI myocardial SPECT. Ann Nucl Med2001;15(4):381\u20135."},{"issue":"3","key":"i0730-2347-42-4-381-b7","series-title":"Int Heart J","first-page":"399","article-title":"Misdiagnosis: cardiac metastasis presented as a pseudo-infarction on electrocardiography","volume":"48","year":"2007","unstructured":"Pan\n              KL, \n            \n              Wu\n              LS, \n            \n              Chung\n              CM, \n            \n              Chang\n              ST, \n            \n              Lin\n              PC, \n            \n              Hsu\n              JT.\n            \n          \n          Misdiagnosis: cardiac metastasis presented as a pseudo-infarction on electrocardiography. Int Heart J2007;48(3):399\u2013405."},{"issue":"11","key":"i0730-2347-42-4-381-b8","series-title":"J Am Soc Echocardiogr","first-page":"1198","article-title":"Lung neoplasm mimicking an acute lateral myocardial infarction","volume":"16","year":"2003","unstructured":"Rodrigues\n              AC, \n            \n              Abreu\n              E, \n            \n              Demarchi\n              LM, \n            \n              Mathias\n              W\n              Jr\n            , LealSM, AndradeJL.\n          Lung neoplasm mimicking an acute lateral myocardial infarction. J Am Soc Echocardiogr2003;16(11): 1198\u2013200."},{"issue":"1","key":"i0730-2347-42-4-381-b9","series-title":"Am J Emerg Med","first-page":"86","article-title":"Lung cancer mimicking acute myocardial infarction on electrocardiogram","volume":"17","year":"1999","unstructured":"Yao\n              NS, \n            \n              Hsu\n              YM, \n            \n              Liu\n              JM, \n            \n              Chen\n              LT, \n            \n              Liau\n              CS.\n            \n          \n          Lung cancer mimicking acute myocardial infarction on electrocardiogram. Am J Emerg Med1999;17(1):86\u20138."},{"issue":"5","key":"i0730-2347-42-4-381-b10","series-title":"Clin Cardiol","first-page":"360","article-title":"External compression by metastatic squamous cell carcinoma: a rare cause of left main coronary artery narrowing","volume":"13","year":"1990","unstructured":"Weinberg\n              BA, \n            \n              Pinkerton\n              CA, \n            \n              Waller\n              BF.\n            \n          \n          External compression by metastatic squamous cell carcinoma: a rare cause of left main coronary artery narrowing. Clin Cardiol1990;13(5): 360\u20136."},{"key":"i0730-2347-42-4-381-b11","series-title":"Am J Cardiol","first-page":"200","article-title":"Electrocardiographic findings in 67,375 asymptomatic subjects. X. Normal values","volume":"6","year":"1960","unstructured":"Hiss\n              RG, \n            \n              Lamb\n              LE, \n            \n              Allen\n              MF.\n            \n          \n          Electrocardiographic findings in 67,375 asymptomatic subjects. X. Normal values. Am J Cardiol1960;6:200\u201331."},{"issue":"9","key":"i0730-2347-42-4-381-b12","series-title":"JAMA","first-page":"1150","article-title":"Acute pericarditis: current concepts and practice","volume":"289","year":"2003","unstructured":"Spodick\n              DH.\n            \n          \n          Acute pericarditis: current concepts and practice. JAMA2003;289(9):1150\u20133."},{"issue":"1","key":"i0730-2347-42-4-381-b13","series-title":"J Electrocardiol","first-page":"53","article-title":"The hyperkalemic Brugada sign","volume":"40","year":"2007","unstructured":"Littmann\n              L, \n            \n              Monroe\n              MH, \n            \n              Taylor\n              L\n              3rd\n            , BrearleyWDJr.\n          The hyperkalemic Brugada sign. J Electrocardiol2007;40(1):53\u20139."},{"issue":"7","key":"i0730-2347-42-4-381-b14","series-title":"Am J Cardiol","first-page":"807","article-title":"Diagnostic value of the electrocardiogram in suspected pulmonary embolism","volume":"86","year":"2000","unstructured":"Rodger\n              M, \n            \n              Makropoulos\n              D, \n            \n              Turek\n              M, \n            \n              Quevillon\n              J, \n            \n              Raymond\n              F, \n            \n              Rasuli\n              P, \n            \n              Wells\n              PS.\n            \n          \n          Diagnostic value of the electrocardiogram in suspected pulmonary embolism. Am J Cardiol2000;86(7):807\u20139, A10."},{"issue":"3","key":"i0730-2347-42-4-381-b15","series-title":"Int J Cardiol","first-page":"341","article-title":"ST-segment changes after direct current external cardioversion for atrial fibrillation. Incidence, characteristics and predictive factors","volume":"148","year":"2011","unstructured":"Rumeau\n              P, \n            \n              Fourcade\n              J, \n            \n              Duparc\n              A, \n            \n              Hebrard\n              A, \n            \n              Mondoly\n              P, \n            \n              Rollin\n              A, \n          \n          et al. ST-segment changes after direct current external cardioversion for atrial fibrillation. Incidence, characteristics and predictive factors. Int J Cardiol2011;148(3):341\u20136."},{"issue":"10","key":"i0730-2347-42-4-381-b16","series-title":"Arch Intern Med","first-page":"1917","article-title":"Pronounced and prolonged ST segment elevation: a pathognomonic sign of tumor invasion of the heart","volume":"142","year":"1982","unstructured":"Hartman\n              RB, \n            \n              Clark\n              PI, \n            \n              Schulman\n              P.\n            \n          \n          Pronounced and prolonged ST segment elevation: a pathognomonic sign of tumor invasion of the heart. Arch Intern Med1982;142(10):1917\u20139."}],"container-title":["Texas Heart Institute Journal"],"original-title":[],"link":[{"URL":"https:\/\/thij.kglmeridian.com\/view\/journals\/thij\/42\/4\/article-p381.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/meridian.allenpress.com\/thij\/article-pdf\/42\/4\/381\/2325291\/thij-14-4268.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thij.kglmeridian.com\/downloadpdf\/journals\/thij\/42\/4\/article-p381.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thij.kglmeridian.com\/downloadpdf\/journals\/thij\/42\/4\/article-p381.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,7]],"date-time":"2024-11-07T15:30:41Z","timestamp":1730993441000},"score":1,"resource":{"primary":{"URL":"https:\/\/thij.kglmeridian.com\/view\/journals\/thij\/42\/4\/article-p381.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,8]]},"references-count":16,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.14503\/thij-14-4268","relation":{},"ISSN":["0730-2347","1526-6702"],"issn-type":[{"type":"print","value":"0730-2347"},{"type":"electronic","value":"1526-6702"}],"subject":[],"published":{"date-parts":[[2015,8]]}}}