{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T13:23:29Z","timestamp":1785763409274,"version":"3.56.0"},"reference-count":15,"publisher":"Texas Heart Institute Journal","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,10]]},"abstract":"<jats:p>Stent thrombosis is a life-threatening sequela of drug-eluting stent implantation. Dual antiplatelet therapy with aspirin and thienopyridine is typically used to prevent this catastrophic event. In terms of stent thrombosis, the major concern is the variable response of patients to clopidogrel, and this has raised interest in new antiplatelet agents. We present the case of a 64-year-old woman whom we successfully treated with prasugrel after she had repeated episodes of stent thrombosis caused by a poor response to clopidogrel. This case highlights the potential role of new antiplatelet agents for patients who are undergoing drug-eluting stent implantation.<\/jats:p>","DOI":"10.14503\/thij-14-4491","type":"journal-article","created":{"date-parts":[[2015,10,1]],"date-time":"2015-10-01T20:24:07Z","timestamp":1443731047000},"page":"483-486","source":"Crossref","is-referenced-by-count":5,"title":["Successful Prasugrel Therapy for Recurrent Left Main Stent Thrombosis in a Clopidogrel Hyporesponder"],"prefix":"10.14503","volume":"42","author":[{"given":"Yi-Sik","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang-Rok","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5628","reference":[{"issue":"3","key":"i0730-2347-42-5-483-b1","series-title":"Int J Cardiol","first-page":"e51","article-title":"Stent thrombosis: nightmare of the interventional cardiology era","volume":"148","year":"2011","unstructured":"Karakurt\n              O, \n            \n              Akdemir\n              R.\n            \n          \n          Stent thrombosis: nightmare of the interventional cardiology era. 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Nat Clin Pract Cardiovasc Med2006;3(7):387\u201395."},{"issue":"4","key":"i0730-2347-42-5-483-b4","series-title":"Am J Cardiol","first-page":"456","article-title":"Frequency of nonresponse antiplatelet activity of clopidogrel during pretreatment for cardiac catheterization","volume":"93","year":"2004","unstructured":"Mobley\n              JE, \n            \n              Bresee\n              SJ, \n            \n              Wortham\n              DC, \n            \n              Craft\n              RM, \n            \n              Snider\n              CC, \n            \n              Carroll\n              RC.\n            \n          \n          Frequency of nonresponse antiplatelet activity of clopidogrel during pretreatment for cardiac catheterization. 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Randomized comparison of adjunctive cilostazol versus high maintenance dose clopidogrel in patients with high post-treatment platelet reactivity: results of the ACCEL-RESISTANCE (Adjunctive Cilostazol versus High Maintenance Dose Clopidogrel in Patients with Clopidogrel Resistance) randomized study. J Am Coll Cardiol2009;53(13):1101\u20139."},{"issue":"10","key":"i0730-2347-42-5-483-b8","series-title":"J Am Coll Cardiol","first-page":"1833","article-title":"Triple versus dual antiplatelet therapy after coronary stenting: impact on stent thrombosis","volume":"46","year":"2005","unstructured":"Lee\n              SW, \n            \n              Park\n              SW, \n            \n              Hong\n              MK, \n            \n              Kim\n              YH, \n            \n              Lee\n              BK, \n            \n              Song\n              JM, \n          \n          et al. Triple versus dual antiplatelet therapy after coronary stenting: impact on stent thrombosis. J Am Coll Cardiol2005;46 (10):1833\u20137."},{"issue":"3","key":"i0730-2347-42-5-483-b9","series-title":"J Am Coll Cardiol","first-page":"280","article-title":"Multicenter randomized trial evaluating the efficacy of cilostazol on ischemic vascular complications after drug-eluting stent implantation for coronary heart disease: results of the CILON-T (influence of CILostazol-based triple antiplatelet therapy ON ischemic complication after drug-eluting stenT implantation) trial","volume":"57","year":"2011","unstructured":"Suh\n              JW, \n            \n              Lee\n              SP, \n            \n              Park\n              KW, \n            \n              Lee\n              HY, \n            \n              Kang\n              HJ, \n            \n              Koo\n              BK, \n          \n          et al. Multicenter randomized trial evaluating the efficacy of cilostazol on ischemic vascular complications after drug-eluting stent implantation for coronary heart disease: results of the CILON-T (influence of CILostazol-based triple antiplatelet therapy ON ischemic complication after drug-eluting stenT implantation) trial. J Am Coll Cardiol2011;57(3):280\u20139."},{"issue":"20","key":"i0730-2347-42-5-483-b10","series-title":"N Engl J Med","first-page":"2001","article-title":"Prasugrel versus clopidogrel in patients with acute coronary syndromes","volume":"357","year":"2007","unstructured":"Wiviott\n              SD, \n            \n              Braunwald\n              E, \n            \n              McCabe\n              CH, \n            \n              Montalescot\n              G, \n            \n              Ruzyllo\n              W, \n            \n              Gottlieb\n              S, \n          \n          et al. 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