{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T01:56:52Z","timestamp":1779155812724,"version":"3.51.4"},"reference-count":42,"publisher":"Texas Heart Institute Journal","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,6]]},"abstract":"<jats:p>A 4-year-old boy had a 15-mm atrial septal defect repaired percutaneously with use of an A<jats:sc>mplatzer<\/jats:sc> Septal Occluder. At age 16 years, he presented with a week's history of fever, chills, dyspnea, fatigue, and malaise. Cultures grew methicillin-sensitive <jats:italic>Staphylococcus aureus<\/jats:italic>. A transesophageal echocardiogram showed a 1.25 \u00d7 1.5-cm pedunculated mass on the left aspect of the atrial septum just superior to the mitral valve, and a smaller vegetation on the right inferior medial aspect of the septum. At surgery, visual examination of both sides of the septum revealed granulation tissue, the pedunculated mass, the small vegetation, and exposed metal wires that suggested incomplete endothelialization of the occluder. We removed the occluder and patched the septal defect. The patient returned to full activity after 4 months and was asymptomatic 3 years postoperatively.<\/jats:p>\n        <jats:p>Our report reinforces the need for further investigation into prosthetic device endothelialization, endocarditis prophylaxis, and recommended levels of physical activity in patients whose devices might be incompletely endothelialized. In addition to reporting our patient's case, we review the medical literature on this topic.<\/jats:p>","DOI":"10.14503\/thij-14-4949","type":"journal-article","created":{"date-parts":[[2016,6,6]],"date-time":"2016-06-06T16:11:30Z","timestamp":1465229490000},"page":"227-231","source":"Crossref","is-referenced-by-count":16,"title":["Endocarditis and Incomplete Endothelialization 12 Years after Amplatzer Septal Occluder Deployment"],"prefix":"10.14503","volume":"43","author":[{"given":"Allan K.","family":"Nguyen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian A.","family":"Palafox","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joanne P.","family":"Starr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard N.","family":"Gates","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farbouch","family":"Berdjis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5628","reference":[{"issue":"2","key":"i1526-6702-43-3-227-b1","series-title":"Curr Opin Cardiol","first-page":"84","article-title":"Interventional approach to congenital heart disease","volume":"19","year":"2004","unstructured":"Holzer\n              R, \n            \n              Hijazi\n              ZM.\n            \n          \n          Interventional approach to congenital heart disease. 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Catheter Cardiovasc Interv2001;53(3):386\u201391."},{"issue":"4","key":"i1526-6702-43-3-227-b5","series-title":"Arq Bras Cardiol","first-page":"384","article-title":"Effectiveness of the Amplatzer device for transcatheter closure of an ostium secundum atrial septal defect [in Portuguese]","volume":"88","year":"2007","unstructured":"Cardoso\n              CO, \n            \n              Rossi Filho\n              RI, \n            \n              Machado\n              PR, \n            \n              Francois\n              LM, \n            \n              Horowitz\n              ES, \n            \n              Sarmento-Leite\n              R.\n            \n          \n          Effectiveness of the Amplatzer device for transcatheter closure of an ostium secundum atrial septal defect [in Portuguese]. Arq Bras Cardiol2007;88(4):384\u20139."},{"issue":"1","key":"i1526-6702-43-3-227-b6","series-title":"Congenit Heart Dis","first-page":"32","article-title":"Long-term follow up of secundum atrial septal defect closure with the Amplatzer septal occluder","volume":"5","year":"2010","unstructured":"Knepp\n              MD, \n            \n              Rocchini\n              AP, \n            \n              Lloyd\n              TR, \n            \n              Aiyagari\n              RM.\n            \n          \n          Long-term follow up of secundum atrial septal defect closure with the Amplatzer septal occluder. 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