{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T11:19:30Z","timestamp":1781781570998,"version":"3.54.5"},"reference-count":16,"publisher":"Texas Heart Institute Journal","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:p>Interrupted aortic arch is a rare congenital abnormality with a high infancy mortality rate. The principal finding is loss of luminal continuity between the ascending and descending portions of the aorta. Because of the high mortality rate in infancy, interrupted aortic arch is very rare among adults. In this report, we describe the case of a 76-year-old woman with asymptomatic interrupted aortic arch, severe tricuspid regurgitation, and bicuspid aortic valve. To our knowledge, she is the oldest patient ever reported with this possibly unique combination of pathologic conditions. In addition to reporting her case, we review the relevant medical literature.<\/jats:p>","DOI":"10.14503\/thij-15-5320","type":"journal-article","created":{"date-parts":[[2016,10,12]],"date-time":"2016-10-12T17:03:44Z","timestamp":1476291824000},"page":"437-440","source":"Crossref","is-referenced-by-count":4,"title":["Asymptomatic Interrupted Aortic Arch, Severe Tricuspid Regurgitation, and Bicuspid Aortic Valve in a 76-Year-Old Woman"],"prefix":"10.14503","volume":"43","author":[{"given":"Masih","family":"Tajdini","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akram","family":"Sardari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seyed Khalil","family":"Forouzannia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdolvahab","family":"Baradaran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seyed Mohammad Reza","family":"Hosseini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seyed Ebrahim","family":"Kassaian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5628","reference":[{"issue":"5","key":"i1526-6702-43-5-437-b1","series-title":"Tex Heart Inst J","first-page":"559","article-title":"Isolated type A interrupted aortic arch in an asymptomatic 19-year-old man","volume":"38","year":"2011","unstructured":"Bugan\n              B, \n            \n              Iyisoy\n              A, \n            \n              Celik\n              M, \n            \n              Kucuk\n              U, \n            \n              Boz\n              U, \n            \n              Celik\n              T.\n            \n          \n          Isolated type A interrupted aortic arch in an asymptomatic 19-year-old man. Tex Heart Inst J2011;38(5):559\u201361."},{"issue":"6","key":"i1526-6702-43-5-437-b2","series-title":"Rev Port Cardiol","first-page":"389.e1","article-title":"Interrupted aortic arch: a misdiagnosed cause of hypertension","volume":"33","year":"2014","unstructured":"Ponte\n              M, \n            \n              Dias\n              A, \n            \n              Dias Ferreira\n              N, \n            \n              Fonseca\n              C, \n            \n              Mota\n              JC, \n            \n              Gama\n              V.\n            \n          \n          Interrupted aortic arch: a misdiagnosed cause of hypertension. Rev Port Cardiol2014;33(6):389.e1\u20135."},{"issue":"3","key":"i1526-6702-43-5-437-b3","series-title":"Thorac Cardiovasc Surg","first-page":"140","article-title":"Interrupted aortic arch in adulthood","volume":"56","year":"2008","unstructured":"Hokenek\n              F, \n            \n              Sever\n              K, \n            \n              Ugurlucan\n              M, \n            \n              Sakliyan\n              M, \n            \n              Kinoglu\n              B.\n            \n          \n          Interrupted aortic arch in adulthood. Thorac Cardiovasc Surg2008;56(3):140\u20132."},{"issue":"2","key":"i1526-6702-43-5-437-b4","series-title":"Tex Heart Inst J","first-page":"118","article-title":"Interrupted aortic arch in an adult: single-stage extra-anatomic repair","volume":"29","year":"2002","unstructured":"Messner\n              G, \n            \n              Reul\n              GJ, \n            \n              Flamm\n              SD, \n            \n              Gregoric\n              ID, \n            \n              Opfermann\n              UT.\n            \n          \n          Interrupted aortic arch in an adult: single-stage extra-anatomic repair. Tex Heart Inst J2002;29(2):118\u201321."},{"issue":"6","key":"i1526-6702-43-5-437-b5","series-title":"J Pediatr","first-page":"959","article-title":"Interrupted aortic arch in infancy","volume":"88","year":"1976","unstructured":"Collins-Nakai\n              RL, \n            \n              Dick\n              M, \n            \n              Parisi-Buckley\n              L, \n            \n              Fyler\n              DC, \n            \n              Castaneda\n              AR.\n            \n          \n          Interrupted aortic arch in infancy. J Pediatr1976;88(6):959\u201362."},{"issue":"1","key":"i1526-6702-43-5-437-b6","series-title":"Arq Bras Cardiol","first-page":"e4","article-title":"Interrupted aortic arch with cardiac heart failure in young adult","volume":"91","year":"2008","unstructured":"Lobato\n              RF, \n            \n              Saliba\n              LA, \n            \n              Ferreiro\n              CR, \n            \n              Bacal\n              F.\n            \n          \n          Interrupted aortic arch with cardiac heart failure in young adult. Arq Bras Cardiol2008;91(1):e4\u20136."},{"issue":"3","key":"i1526-6702-43-5-437-b7","series-title":"Tex Heart Inst J","first-page":"250","article-title":"Interrupted aortic arch: brief review and summary of an eighteen-year experience","volume":"11","year":"1984","unstructured":"Reardon\n              MJ, \n            \n              Hallman\n              GL, \n            \n              Cooley\n              DA.\n            \n          \n          Interrupted aortic arch: brief review and summary of an eighteen-year experience. Tex Heart Inst J1984;11(3):250\u20139."},{"issue":"2","key":"i1526-6702-43-5-437-b8","series-title":"Turk Kardiyol Dern Ars","first-page":"141","article-title":"A case of aortic coarctation mimicking interrupted aorta [in Turkish]","volume":"37","year":"2009","unstructured":"Ozdogru\n              I, \n            \n              Gunebakmaz\n              O, \n            \n              Kaya\n              MG, \n            \n              Dogan\n              A.\n            \n          \n          A case of aortic coarctation mimicking interrupted aorta [in Turkish]. Turk Kardiyol Dern Ars2009;37(2):141\u20134."},{"issue":"5","key":"i1526-6702-43-5-437-b9","series-title":"Int J Cardiovasc Imaging","first-page":"389","article-title":"Isolated interrupted aortic arch: a case report and review of the literature","volume":"20","year":"2004","unstructured":"Akdemir\n              R, \n            \n              Ozhan\n              H, \n            \n              Erbilen\n              E, \n            \n              Yazici\n              M, \n            \n              Gunduz\n              H, \n            \n              Uyan\n              C.\n            \n          \n          Isolated interrupted aortic arch: a case report and review of the literature. Int J Cardiovasc Imaging2004;20(5):389\u201392."},{"issue":"3","key":"i1526-6702-43-5-437-b10","series-title":"Br Heart J","first-page":"294","article-title":"Isolated atresia of the aortic arch in a 65-year-old man. Surgical treatment and review of published reports","volume":"47","year":"1982","unstructured":"Milo\n              S, \n            \n              Massini\n              C, \n            \n              Goor\n              DA.\n            \n          \n          Isolated atresia of the aortic arch in a 65-year-old man. Surgical treatment and review of published reports. Br Heart J1982;47(3):294\u20137."},{"issue":"1\u20132","key":"i1526-6702-43-5-437-b11","series-title":"Schweiz Med Wochenschr","first-page":"26","article-title":"Interrupted aortic arch: fortuitous diagnosis in a 72-year-old female patient with severe aortic insufficiency [in German]","volume":"125","year":"1995","unstructured":"Canova\n              CR, \n            \n              Carrel\n              T, \n            \n              Dubach\n              P, \n            \n              Turina\n              M, \n            \n              Reinhart\n              WH.\n            \n          \n          Interrupted aortic arch: fortuitous diagnosis in a 72-year-old female patient with severe aortic insufficiency [in German]. Schweiz Med Wochenschr1995;125(1\u20132):26\u201330."},{"issue":"2","key":"i1526-6702-43-5-437-b12","series-title":"Tex Heart Inst J","first-page":"147","article-title":"Interruption of aortic arch in adults: surgical experience with extra-anatomic bypass","volume":"32","year":"2005","unstructured":"Sai Krishna\n              C, \n            \n              Bhan\n              A, \n            \n              Sharma\n              S, \n            \n              Kiran\n              U, \n            \n              Venugopal\n              P.\n            \n          \n          Interruption of aortic arch in adults: surgical experience with extra-anatomic bypass. Tex Heart Inst J2005;32(2):147\u201350."},{"issue":"Suppl 1","key":"i1526-6702-43-5-437-b13","series-title":"Coll Antropol","first-page":"307","article-title":"Secondary hypertension due to isolated interrupted aortic arch in a 60-year-old person--one-year follow up","volume":"34","year":"2010","unstructured":"Mirat\n              J, \n            \n              Galic\n              E, \n            \n              Coric\n              V, \n            \n              Rajsman\n              G, \n            \n              Vrbanic\n              L, \n            \n              Razov Radas\n              M, \n          \n          et al. Secondary hypertension due to isolated interrupted aortic arch in a 60-year-old person--one-year follow up. Coll Antropol2010;34Suppl 1:307\u20139."},{"key":"i1526-6702-43-5-437-b14","series-title":"Case Rep Crit Care","first-page":"989621","article-title":"Isolated interrupted aortic arch: unexpected diagnosis in a 63-year-old male","volume":"2011","year":"2011","unstructured":"Javadzadegan\n              H, \n            \n              Porhomayon\n              J, \n            \n              Sadighi\n              A, \n            \n              Yavarikia\n              M, \n            \n              Nader\n              N.\n            \n          \n          Isolated interrupted aortic arch: unexpected diagnosis in a 63-year-old male. Case Rep Crit Care2011;2011: 989621."},{"issue":"6","key":"i1526-6702-43-5-437-b15","series-title":"Cardiol J","first-page":"695","article-title":"Silent interrupted aortic arch in an elderly patient","volume":"18","year":"2011","unstructured":"Erden\n              I, \n            \n              Kayapinar\n              O, \n            \n              Erden\n              EC, \n            \n              Yalcin\n              S.\n            \n          \n          Silent interrupted aortic arch in an elderly patient. Cardiol J2011;18(6):695\u20137."},{"issue":"4","key":"i1526-6702-43-5-437-b16","series-title":"ARYA Atheroscler","first-page":"230","article-title":"Undiagnosed interrupted aortic arch in a 59-year-old male patient with severe aortic valve stenosis: a case report and literature review","volume":"10","year":"2014","unstructured":"Mehrpooya\n              M, \n            \n              Eskandari\n              R, \n            \n              Salehi\n              M, \n            \n              Shajirat\n              Z, \n            \n              Golabchi\n              A, \n            \n              Satarzadeh\n              R, \n            \n              Zand-Parsa\n              AF.\n            \n          \n          Undiagnosed interrupted aortic arch in a 59-year-old male patient with severe aortic valve stenosis: a case report and literature review. 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