{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T06:36:51Z","timestamp":1764225411121,"version":"3.28.0"},"reference-count":12,"publisher":"Texas Heart Institute Journal","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:p>The widespread use of continuous-flow left ventricular assist devices for mechanical circulatory support has shown that long-term hemodynamic support is possible, even when a clinical \u201cpulse\u201d cannot be detected. We present the incidental discovery of ventricular fibrillation in 6 alert, hemodynamically stable patients supported only by a continuous-flow device (HeartMate II, n=5; Jarvik 2000, n=1). Ventricular fibrillation was found in 3 patients during routine outpatient follow-up visits and in 3 awaiting discharge from the hospital after device placement. Diagnosis was confirmed by electrocardiographic and echocardiographic studies.<\/jats:p>\n        <jats:p>The average duration of mechanical circulatory support before ventricular fibrillation occurred was 221 \u00b1 362 days (range, 5\u2013864 d). All patients were conscious and ambulatory at the time of the arrhythmia. Three patients reported symptoms\u2014primarily fatigue, nausea, and exertional dyspnea\u2014that prompted evaluation. Serum chemistry analysis of blood drawn immediately after diagnosis showed no changes that suggested end-organ dysfunction. Three patients died of unrelated complications an average of 3.9 yr (range, 360\u20132,270 d) after the event. Two of the remaining 3 patients eventually underwent successful pump explantation, and one is on ongoing support.<\/jats:p>\n        <jats:p>Our experience shows that it is possible for patients with continuous-flow left ventricular assist devices to remain hemodynamically stable while in ventricular fibrillation. Additional investigation is needed to determine whether defibrillator settings for these patients should be adjusted to limit delivery of shock therapy.<\/jats:p>","DOI":"10.14503\/thij-16-5879","type":"journal-article","created":{"date-parts":[[2017,10,31]],"date-time":"2017-10-31T21:07:00Z","timestamp":1509484020000},"page":"357-360","source":"Crossref","is-referenced-by-count":8,"title":["Tolerance of Sustained Ventricular Fibrillation During Continuous-Flow Left Ventricular Assist Device Support"],"prefix":"10.14503","volume":"44","author":[{"given":"Andrew C.W.","family":"Baldwin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Courtney J.","family":"Gemmato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Sandoval","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William E.","family":"Cohn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey A.","family":"Morgan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.H.","family":"Frazier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5628","reference":[{"issue":"8","key":"i1526-6702-44-5-357-b1","series-title":"Am J Cardiol","first-page":"1151","article-title":"Ventricular arrhythmias during left ventricular assist device support","volume":"99","year":"2007","unstructured":"Bedi\n              M\n            , KormosR, WinowichS, McNamaraDM, MathierMA, MuraliS.\n          Ventricular arrhythmias during left ventricular assist device support. 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Destination therapy with a rotary blood pump and novel power delivery. Eur J Cardiothorac Surg2010;37(2):350\u20136."},{"issue":"4","key":"i1526-6702-44-5-357-b11","series-title":"J Thorac Cardiovasc Surg","first-page":"625","article-title":"Biventricular assistance with the Jarvik FlowMaker: a case report","volume":"128","year":"2004","unstructured":"Frazier\n              OH\n            , MyersTJ, GregoricI.\n          Biventricular assistance with the Jarvik FlowMaker: a case report. J Thorac Cardiovasc Surg2004;128(4):625\u20136."},{"issue":"4","key":"i1526-6702-44-5-357-b12","series-title":"J Thorac Cardiovasc Surg","first-page":"936","article-title":"Successful use of the HeartWare HVAD rotary blood pump for biventricular support","volume":"140","year":"2010","unstructured":"Strueber\n              M\n            , MeyerAL, MalehsaD, HaverichA.\n          Successful use of the HeartWare HVAD rotary blood pump for biventricular support. 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