{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T17:24:48Z","timestamp":1761845088880,"version":"3.28.0"},"reference-count":7,"publisher":"Texas Heart Institute Journal","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:p>Bioprosthetic valve thrombosis was previously considered to be a relatively rare complication of surgical or transcatheter bioprosthetic valve replacement. Although echocardiograms can reliably show the characteristic findings of prosthetic valve stenosis, differentiating between thrombus formation and pannus overgrowth as the underlying cause of prosthetic valve dysfunction can be challenging.<\/jats:p>\n        <jats:p>We present the case of a 75-year-old man who underwent transthoracic Doppler echocardiography in the presence of an elevated valvular gradient 2 years after his aortic valve had been surgically replaced with a bioprosthesis. The echocardiographic findings suggested prosthetic valve stenosis. Cardiac computed tomography, performed to distinguish between thrombus formation and pannus overgrowth, revealed hypoattenuated leaflet thickening and reduced leaflet mobility, which suggested thrombus. After the patient took oral anticoagulants for 3 months, images showed complete resolution of the previous abnormalities, thus confirming the diagnosis of bioprosthetic valve thrombosis. We found cardiac computed tomography valuable when evaluating our patient who had an elevated prosthetic valve gradient.<\/jats:p>","DOI":"10.14503\/thij-17-6459","type":"journal-article","created":{"date-parts":[[2019,10,31]],"date-time":"2019-10-31T15:59:21Z","timestamp":1572537561000},"page":"219-221","source":"Crossref","is-referenced-by-count":3,"title":["Use of Computed Tomography to Distinguish Thrombus from Pannus on a Bioprosthetic Aortic Valve"],"prefix":"10.14503","volume":"46","author":[{"given":"Jessica V.","family":"Kealhofer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeremy S.","family":"Markowitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prabhjot S.","family":"Nijjar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5628","reference":[{"issue":"10087","key":"i1526-6702-46-3-219-b1","series-title":"Lancet","first-page":"2383","article-title":"Subclinical leaflet thrombosis in surgical and transcatheter bioprosthetic aortic valves: an observational study","volume":"389","year":"2017","unstructured":"Chakravarty\n              T\n            , SondergaardL, FriedmanJ, De BackerO, BermanD, KofoedKF, \n          et al. Subclinical leaflet thrombosis in surgical and transcatheter bioprosthetic aortic valves: an observational study. Lancet2017;389(10087):2383\u201392."},{"issue":"21","key":"i1526-6702-46-3-219-b2","series-title":"J Am Coll Cardiol","first-page":"2285","article-title":"Bioprosthetic valve thrombosis versus structural failure: clinical and echocardiographic predictors","volume":"66","year":"2015","unstructured":"Egbe\n              AC\n            , PislaruSV, PellikkaPA, PoteruchaJT, SchaffHV, MaleszewskiJJ, ConnollyHM.\n          Bioprosthetic valve thrombosis versus structural failure: clinical and echocardiographic predictors. J Am Coll Cardiol2015;66(21):2285\u201394."},{"issue":"21","key":"i1526-6702-46-3-219-b3","series-title":"N Engl J Med","first-page":"2015","article-title":"Possible subclinical leaflet thrombosis in bioprosthetic aortic valves","volume":"373","year":"2015","unstructured":"Makkar\n              RR\n            , FontanaG, JilaihawiH, ChakravartyT, KofoedKF, De BackerO, \n          et al. Possible subclinical leaflet thrombosis in bioprosthetic aortic valves. N Engl J Med2015;373(21):2015\u201324."},{"issue":"4","key":"i1526-6702-46-3-219-b4","series-title":"JACC Cardiovasc Interv","first-page":"379","article-title":"Outcomes of warfarin therapy for bio-prosthetic valve thrombosis of surgically implanted valves: a prospective study","volume":"10","year":"2017","unstructured":"Egbe\n              AC\n            , ConnollyHM, PellikkaPA, SchaffHV, HannaR, MaleszewskiJJ, \n          et al. Outcomes of warfarin therapy for bio-prosthetic valve thrombosis of surgically implanted valves: a prospective study. JACC Cardiovasc Interv2017;10(4):379\u201387."},{"issue":"22","key":"i1526-6702-46-3-219-b5","series-title":"J Am Coll Cardiol","first-page":"2438","article-title":"2014 AHA\/ACC guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines [published erratum appears in J Am Coll Cardiol 2014;63(22):2489]","volume":"63","year":"2014","unstructured":"Nishimura\n              RA\n            , OttoCM, BonowRO, CarabelloBA, ErwinJP3rd, GuytonRA, \n          et al. 2014 AHA\/ACC guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines [published erratum appears in J Am Coll Cardiol 2014;63(22):2489]. J Am Coll Cardiol2014;63(22):2438\u201388."},{"issue":"24","key":"i1526-6702-46-3-219-b6","series-title":"J Am Coll Cardiol","first-page":"2670","article-title":"Prosthetic heart valve thrombosis","volume":"68","year":"2016","unstructured":"Dangas\n              GD\n            , WeitzJI, GiustinoG, MakkarR, MehranR.\n          Prosthetic heart valve thrombosis. J Am Coll Cardiol2016;68(24):2670\u201389."},{"issue":"4","key":"i1526-6702-46-3-219-b7","series-title":"JACC Cardiovasc Imaging","first-page":"461","article-title":"Systematic CT methodology for the evaluation of subclinical leaflet thrombosis","volume":"10","year":"2017","unstructured":"Jilaihawi\n              H\n            , AschFM, ManasseE, RuizCE, JelninV, KashifM, \n          et al. Systematic CT methodology for the evaluation of subclinical leaflet thrombosis. JACC Cardiovasc Imaging2017;10(4):461\u201370."}],"container-title":["Texas Heart Institute Journal"],"original-title":[],"link":[{"URL":"https:\/\/thij.kglmeridian.com\/view\/journals\/thij\/46\/3\/article-p219.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/meridian.allenpress.com\/thij\/article-pdf\/46\/3\/219\/2445167\/thij-17-6459.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thij.kglmeridian.com\/downloadpdf\/journals\/thij\/46\/3\/article-p219.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thij.kglmeridian.com\/downloadpdf\/journals\/thij\/46\/3\/article-p219.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,7]],"date-time":"2024-11-07T15:34:53Z","timestamp":1730993693000},"score":1,"resource":{"primary":{"URL":"https:\/\/thij.kglmeridian.com\/view\/journals\/thij\/46\/3\/article-p219.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6]]},"references-count":7,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.14503\/thij-17-6459","relation":{},"ISSN":["0730-2347","1526-6702"],"issn-type":[{"type":"print","value":"0730-2347"},{"type":"electronic","value":"1526-6702"}],"subject":[],"published":{"date-parts":[[2019,6]]}}}