{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T23:24:46Z","timestamp":1778541886671,"version":"3.51.4"},"reference-count":22,"publisher":"Texas Heart Institute Journal","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:p>\n          <jats:italic>Abiotrophia defectiva<\/jats:italic>, a nutritionally deficient streptococcus, is a rare cause of infective endocarditis. It has been associated with hemophagocytic syndrome. We present the first case of <jats:italic>A. defectiva<\/jats:italic> infective endocarditis that led to antineutrophil cytoplasmic antibody-associated glomerulonephritis. The patient was a 55-year-old man whose endocarditis affected the mitral and aortic valves. His course was complicated by atrial fibrillation, stroke, and glomerulonephritis. He was successfully treated with antibiotics and dual valve replacement.<\/jats:p>","DOI":"10.14503\/thij-17-6575","type":"journal-article","created":{"date-parts":[[2020,2,21]],"date-time":"2020-02-21T19:49:05Z","timestamp":1582314545000},"page":"35-37","source":"Crossref","is-referenced-by-count":9,"title":["Double-Valve Heart Disease and Glomerulonephritis Consequent to Abiotrophia defectiva Endocarditis"],"prefix":"10.14503","volume":"47","author":[{"given":"Ahmad Ramy","family":"Elashery","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Stratidis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Apranta Deka","family":"Patel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5628","reference":[{"key":"i1526-6702-47-1-35-b1","series-title":"Nature","first-page":"728","article-title":"Spontaneous development of L forms of streptococci requiring secretions of other bacteria or sulphydryl compounds for normal growth","volume":"191","year":"1961","unstructured":"Frenkel\n              A\n            , HirschW.\n          Spontaneous development of L forms of streptococci requiring secretions of other bacteria or sulphydryl compounds for normal growth. Nature1961;191:728\u201330."},{"issue":"4","key":"i1526-6702-47-1-35-b2","series-title":"Int J Syst Bacteriol","first-page":"798","article-title":"Transfer of Streptococcus adjacens and Streptococcus defectivus to Abiotrophia gen. nov. as Abiotrophia adiacens comb. nov. and Abiotrophia defectiva comb. nov., respectively","volume":"45","year":"1995","unstructured":"Kawamura\n              Y\n            , HouXG, SultanaF, LiuS, YamamotoH, EzakiT.\n          Transfer of Streptococcus adjacens and Streptococcus defectivus to Abiotrophia gen. nov. as Abiotrophia adiacens comb. nov. and Abiotrophia defectiva comb. nov., respectively. Int J Syst Bacteriol1995;45(4):798\u2013803."},{"issue":"2","key":"i1526-6702-47-1-35-b3","series-title":"Clin Microbiol Rev","first-page":"184","article-title":"Nutritionally variant streptococci","volume":"4","year":"1991","unstructured":"Ruoff\n              KL.\n            \n          \n          Nutritionally variant streptococci. Clin Microbiol Rev1991;4(2):184\u201390."},{"issue":"5","key":"i1526-6702-47-1-35-b4","series-title":"Rev Infect Dis","first-page":"908","article-title":"Endocarditis due to nutritionally deficient streptococci: therapeutic dilemma","volume":"9","year":"1987","unstructured":"Stein\n              DS\n            , NelsonKE.\n          Endocarditis due to nutritionally deficient streptococci: therapeutic dilemma. Rev Infect Dis1987;9(5):908\u201316."},{"issue":"15","key":"i1526-6702-47-1-35-b5","series-title":"Circulation","first-page":"1435","article-title":"Infective endocarditis in adults: diagnosis, antimicrobial therapy, and management of complications: a scientific statement for healthcare professionals from the American Heart Association","volume":"132","year":"2015","unstructured":"Baddour\n              LM\n            , WilsonWR, BayerAS, FowlerVGJr, TleyjehIM, RybakMJ, \n          et al. 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J Clin Exp Cardiol2013;4(11):276."},{"issue":"7","key":"i1526-6702-47-1-35-b11","series-title":"Am J Med Case Rep","first-page":"187","article-title":"Infective endocarditis caused by Abiotrophia defectiva: a case report","volume":"3","year":"2015","unstructured":"Kadri\n              Y\n            , HassineM, EchahedC, ChaouchC, BoussaadaM, Ben AbdallahH, \n          et al. Infective endocarditis caused by Abiotrophia defectiva: a case report. Am J Med Case Rep2015;3(7):187\u201390."},{"issue":"5","key":"i1526-6702-47-1-35-b12","series-title":"In Vivo","first-page":"515","article-title":"Aortic valve endocarditis caused by Abiotrophia defectiva: case report and literature overview","volume":"29","year":"2015","unstructured":"Carleo\n              MA\n            , Del GiudiceA, VigliettiR, RosarioP, EspositoV.\n          Aortic valve endocarditis caused by Abiotrophia defectiva: case report and literature overview. 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Kidney Int2015;87(6):1241\u20139."},{"issue":"3","key":"i1526-6702-47-1-35-b17","series-title":"Yale J Biol Med","first-page":"373","article-title":"ANCA positivity in a patient with infective endocarditis-associated glomerulonephritis: a diagnostic dilemma","volume":"87","year":"2014","unstructured":"Ghosh\n              GC\n            , SharmaB, KatageriB, BhardwajM.\n          ANCA positivity in a patient with infective endocarditis-associated glomerulonephritis: a diagnostic dilemma. Yale J Biol Med2014;87(3):373\u20137."},{"issue":"2","key":"i1526-6702-47-1-35-b18","series-title":"PLoS One","article-title":"Infective endocarditis with antineutrophil cytoplasmic antibody: report of 13 cases and literature review","volume":"9","year":"2014","unstructured":"Ying\n              CM\n            , YaoDT, DingHH, YangCD.\n          Infective endocarditis with antineutrophil cytoplasmic antibody: report of 13 cases and literature review. 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