{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T08:11:20Z","timestamp":1782375080892,"version":"3.54.5"},"reference-count":13,"publisher":"Texas Heart Institute Journal","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:p>Acute mitral regurgitation is a life-threatening complication of acute myocardial infarction. We present the case of a 70-year-old woman who had acute myocardial infarction complicated by severe mitral regurgitation and cardiogenic shock. Although current guidelines recommend mitral valve surgery for such patients, surgery often carries prohibitive risk of morbidity and mortality. Thus, in certain patients, percutaneous repair may be the only viable treatment option. In this case, we used a 3-step percutaneous approach involving coronary artery revascularization with a drug-eluting stent in the left circumflex coronary artery, mechanical circulatory support with an Impella CP pump for cardiogenic shock, and mitral valve repair with the MitraClip system for severe mitral regurgitation. After successful intervention, our patient regained hemodynamic stability and showed clinical improvement at one-month follow-up.<\/jats:p>","DOI":"10.14503\/thij-18-6901","type":"journal-article","created":{"date-parts":[[2021,1,20]],"date-time":"2021-01-20T23:30:10Z","timestamp":1611185410000},"page":"306-310","source":"Crossref","is-referenced-by-count":7,"title":["MitraClip to Treat Severe Ischemic Mitral Regurgitation During Impella CP Support in a 70-Year-Old Woman"],"prefix":"10.14503","volume":"47","author":[{"given":"Said","family":"Ashraf","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Division of Cardiology, Detroit Medical Center\/Wayne State University, Detroit, Michigan 48201"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomo","family":"Ando","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Cardiology, Detroit Medical Center\/Wayne State University, Detroit, Michigan 48201"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nimrod","family":"Blank","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Cardiology, Detroit Medical Center\/Wayne State University, Detroit, Michigan 48201"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmad","family":"Munir","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Cardiology, Detroit Medical Center\/Wayne State University, Detroit, Michigan 48201"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theodore","family":"Schreiber","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Cardiology, Detroit Medical Center\/Wayne State University, Detroit, Michigan 48201"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5628","reference":[{"issue":"4","key":"i1526-6702-47-4-306-b1","series-title":"Cardiol Clin","first-page":"519","article-title":"Mechanical complications of acute myocardial infarction","volume":"31","year":"2013","unstructured":"Kutty\n              RS,\n            \n            \n              Jones\n              N,\n            \n            \n              Moorjani\n              N.\n            \n          \n          Mechanical complications of acute myocardial infarction.\n\t\t\t\t\tCardiol Clin2013;31(4):519\u201331,\n\t\t\t\t\tvii\u2013viii."},{"issue":"3","key":"i1526-6702-47-4-306-b2","series-title":"Am J Cardiol","first-page":"315","article-title":"Impact of mitral regurgitation on long-term survival after percutaneous coronary intervention","volume":"89","year":"2002","unstructured":"Ellis\n              SG,\n            \n            \n              Whitlow\n              PL,\n            \n            \n              Raymond\n              RE,\n            \n            \n              Schneider\n              JP.\n            \n          \n          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Cardiol2017;120(2):304\u20138."},{"issue":"1","key":"i1526-6702-47-4-306-b7","series-title":"Catheter Cardiovasc Interv","first-page":"E137","article-title":"Successful percutaneous mitral valve repair with the MitraClip system of acute mitral regurgitation due to papillary muscle rupture as complication of acute myocardial infarction","volume":"83","year":"2014","unstructured":"Bilge\n              M,\n            \n            \n              Alemdar\n              R,\n            \n            \n              Yasar\n              AS.\n            \n          \n          Successful percutaneous mitral valve repair with the MitraClip system of acute mitral regurgitation due to papillary muscle rupture as complication of acute myocardial infarction.\n\t\t\t\t\tCatheter Cardiovasc Interv2014;83(1):E137\u201340."},{"issue":"2","key":"i1526-6702-47-4-306-b8","series-title":"Ann Thorac Surg","first-page":"e45","article-title":"Percutaneous repair of postoperative mitral regurgitation after left ventricular assist device implant","volume":"105","year":"2018","unstructured":"Cork\n              DP,\n            \n            \n              Adamson\n              R,\n            \n            \n              Gollapudi\n              R,\n            \n            \n              Dembitsky\n              W,\n            \n            \n              Jaski\n              B.\n            \n          \n          Percutaneous repair of postoperative mitral regurgitation after left ventricular assist device implant.\n\t\t\t\t\tAnn Thorac Surg2018;105(2):e45\u20136."},{"issue":"1","key":"i1526-6702-47-4-306-b9","series-title":"J Am Coll Cardiol","first-page":"91","article-title":"Percutaneous mitral valve repair for acute mitral regurgitation after an acute myocardial infarction","volume":"66","year":"2015","unstructured":"Estevez-Loureiro\n              R,\n            \n            \n              Arzamendi\n              D,\n            \n            \n              Freixa\n    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percutaneous \u201cedge-to-edge\u201d mitral valve repair with MitraClip in a patient with acute post-MI regurgitation not related to papillary muscle rupture.\n\t\t\t\t\tCatheter Cardiovasc Interv2016;88(7):1177\u201380."},{"issue":"1","key":"i1526-6702-47-4-306-b11","series-title":"Am Heart J","first-page":"23","article-title":"The EVEREST II Trial: design and rationale for a randomized study of the evalve MitraClip system compared with mitral valve surgery for mitral regurgitation","volume":"160","year":"2010","unstructured":"Mauri\n              L,\n            \n            \n              Garg\n              P,\n            \n            \n              Massaro\n              JM,\n            \n            \n              Foster\n              E,\n            \n            \n              Glower\n              D,\n            \n            \n              Mehoudar\n              P,\n            \n          \n          .\n\t\t\t\t\tThe EVEREST II Trial: design and rationale for a randomized study of the evalve MitraClip system compared with mitral valve surgery for mitral regurgitation.\n\t\t\t\t\tAm Heart J2010;160(1):23\u20139."},{"issue":"24","key":"i1526-6702-47-4-306-b12","series-title":"N Engl J Med","first-page":"2307","article-title":"Transcatheter mitral-valve repair in patients with heart failure","volume":"379","year":"2018","unstructured":"Stone\n              GW,\n            \n            \n              Lindenfeld\n              J,\n            \n            \n              Abraham\n              WT,\n            \n            \n              Kar\n              S,\n            \n            \n              Lim\n              DS,\n            \n            \n              Mishell\n              JM,\n            \n          \n          .\n\t\t\t\t\tTranscatheter mitral-valve repair in patients with heart failure.\n\t\t\t\t\tN Engl J Med2018;379(24):2307\u201318."},{"issue":"7","key":"i1526-6702-47-4-306-b13","series-title":"JACC Cardiovasc Interv","first-page":"e71","article-title":"Safety of MitraClip implant in the unstable patient: feasibility of concomitant left ventricular support device","volume":"9","year":"2016","unstructured":"Foerst\n              J,\n            \n            \n              Cardenas\n              A,\n            \n            \n              Swank\n              G.\n            \n          \n          Safety of MitraClip implant in the unstable patient: feasibility of concomitant left ventricular support device.\n\t\t\t\t\tJACC Cardiovasc Interv2016;9(7):e71\u20132."}],"container-title":["Texas Heart Institute 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