{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T17:28:53Z","timestamp":1761845333588,"version":"3.28.0"},"reference-count":18,"publisher":"Texas Heart Institute Journal","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:p>Aortic root abscess complicated by infective endocarditis of a mechanical prosthetic valve is associated with morbidity and death. We retrospectively report our experience with a valve-sparing technique for managing this condition.<\/jats:p>\n        <jats:p>From October 2014 through November 2017, 41 patients at our center underwent surgery for aortic root abscess complicated by infective endocarditis of a mechanical prosthetic valve. Twenty (48.7%) met prespecified criteria for use of our valve-sparing technique after careful assessment of the mechanical valve and surrounding tissues. Our technique involved draining the abscess, aggressively d\u00e9briding all infected and necrotic tissues, and then repairing the resulting defect by suturing a Gelweave patch to the healthy aortic wall and to the cuff of the valve.<\/jats:p>\n        <jats:p>We successfully preserved the mechanical aortic valve in all 20 patients. Two (10%) died early (\u226430 d postoperatively) of low cardiac output syndrome with progressive heart failure, superadded septicemia, and multisystem organ failure. At 1-year follow-up, the 18 surviving patients (90%) were symptom free and had a well-functioning mechanical aortic valve with no paravalvular leak.<\/jats:p>\n        <jats:p>We conclude that, in certain patients, our technique for managing aortic root abscess and sparing the mechanical aortic valve is a safe and less time-consuming approach with relatively low mortality and encouraging midterm follow-up outcomes.<\/jats:p>","DOI":"10.14503\/thij-19-7059","type":"journal-article","created":{"date-parts":[[2021,1,20]],"date-time":"2021-01-20T23:20:32Z","timestamp":1611184832000},"page":"280-283","source":"Crossref","is-referenced-by-count":2,"title":["Mechanical Prosthetic Valve Sparing for Aortic Root Abscess Complicated by Infective Endocarditis"],"prefix":"10.14503","volume":"47","author":[{"given":"Ahmed","family":"Ahmed","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Surgery, Faculty of Medicine, Ain Shams University, 11517 Cairo, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayman","family":"Ammar","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Faculty of Medicine, Ain Shams University, 11517 Cairo, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasser","family":"Elnahas","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Faculty of Medicine, Ain Shams University, 11517 Cairo, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammed","family":"Abd Al Jawad","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Faculty of Medicine, Ain Shams University, 11517 Cairo, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5628","reference":[{"issue":"1","key":"i1526-6702-47-4-280-b1","series-title":"Tex Heart Inst J","first-page":"20","article-title":"Surgery for aortic root abscess: a 15-year experience","volume":"43","year":"2016","unstructured":"Kirali\n              K,\n            \n            \n              Sarikaya\n              S,\n            \n            \n              Ozen\n              Y,\n            \n            \n              Sacli\n              H,\n            \n            \n              Basaran\n              E,\n            \n            \n              Yerlikhan\n              OA,\n            \n          \n          .\n\t\t\t\t\tSurgery for aortic root abscess: a 15-year experience.\n\t\t\t\t\tTex Heart Inst J2016;43(1):20\u20138."},{"issue":"10","key":"i1526-6702-47-4-280-b2","series-title":"J Thorac Dis","first-page":"E1213","article-title":"Prosthetic valve endocarditis after transcatheter aortic valve implantation-diagnostic and surgical considerations","volume":"8","year":"2016","unstructured":"Ahmad\n              K,\n            \n            \n              Klaaborg\n              KE,\n            \n            \n              Hjortdal\n              V,\n            \n            \n              Norgaard\n              BL,\n            \n            \n              Terkelsen\n              CJ,\n            \n            \n              Jensen\n              K,\n            \n          \n          .\n\t\t\t\t\tProsthetic valve endocarditis after transcatheter aortic valve implantation-diagnostic and surgical considerations.\n\t\t\t\t\tJ Thorac Dis2016;8(10):E1213\u20138."},{"issue":"7","key":"i1526-6702-47-4-280-b3","series-title":"Am J Cardiol","first-page":"976","article-title":"Clinical characteristics and outcome of aortic endocarditis with periannular abscess in the International Collaboration on Endocarditis Merged Database","volume":"96","year":"2005","unstructured":"Anguera\n              I,\n            \n            \n              Miro\n              JM,\n            \n            \n              Cabell\n              CH,\n            \n            \n              Abrutyn\n              E,\n        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Surg2007;31(1):43\u20138."},{"issue":"5","key":"i1526-6702-47-4-280-b5","series-title":"Arch Intern Med","first-page":"463","article-title":"Clinical presentation, etiology, and outcome of infective endocarditis in the 21st century: the International Collaboration on Endocarditis-Prospective Cohort Study","volume":"169","year":"2009","unstructured":"Murdoch\n              DR,\n            \n            \n              Corey\n              GR,\n            \n            \n              Hoen\n              B,\n            \n            \n              Miro\n              JM,\n            \n            \n              Fowler\n              VG\n              Jr\n            ,\n\t\t\t\t\t\tBayerAS,\n          .\n\t\t\t\t\tClinical presentation, etiology, and outcome of infective endocarditis in the 21st century: the International Collaboration on Endocarditis-Prospective Cohort Study.\n\t\t\t\t\tArch Intern Med2009;169(5):463\u201373."},{"issue":"4","key":"i1526-6702-47-4-280-b6","series-title":"Gen Thorac Cardiovasc Surg","first-page":"175","article-title":"Surgical treatment for aortic periannular abscess\/pseudoaneurysm caused by infective endocarditis","volume":"61","year":"2013","unstructured":"Okada\n              K,\n            \n            \n              Okita\n              Y.\n            \n          \n          Surgical treatment for aortic periannular abscess\/pseudoaneurysm caused by infective endocarditis.\n\t\t\t\t\tGen Thorac Cardiovasc Surg2013;61(4):175\u201381."},{"key":"i1526-6702-47-4-280-b7","series-title":"Annals of Cardiovascular and Thoracic Academy (ACTA)","first-page":"1","article-title":"Aortic root abscess repair in a patient with previous mechanical aortic valve replacement, mitral regurgitation and ischemic heart disease (case report)","volume":"17","year":"2016","unstructured":"Fouad\n              A.\n            \n          \n          Aortic root abscess repair in a patient with previous mechanical aortic valve replacement, mitral regurgitation and ischemic heart disease (case report).\n\t\t\t\t\tAnnals of Cardiovascular and Thoracic Academy (ACTA)2016;17:1\u20135."},{"issue":"3","key":"i1526-6702-47-4-280-b8","series-title":"Am J Cardiol","first-page":"281","article-title":"Prosthetic valve endocarditis: clinicopathological analysis of 22 necropsy patients with comparison of observations in 74 necropsy patients with active infective endocarditis involving natural left-sided cardiac valves","volume":"38","year":"1976","unstructured":"Arnett\n              EN,\n            \n            \n              Roberts\n              WC.\n            \n          \n          Prosthetic valve endocarditis: clinicopathological analysis of 22 necropsy patients with comparison of observations in 74 necropsy patients with active infective endocarditis involving natural left-sided cardiac valves.\n\t\t\t\t\tAm J Cardiol1976;38(3):281\u201392."},{"issue":"2","key":"i1526-6702-47-4-280-b9","series-title":"J Thorac Cardiovasc Surg","first-page":"212","article-title":"Translocation of the aortic valve for prosthetic valve endocarditis","volume":"81","year":"1981","unstructured":"Reitz\n              BA,\n            \n            \n              Stinson\n              EB,\n            \n            \n              Watson\n              DC,\n            \n            \n              Baumgartner\n              WA,\n            \n            \n              Jamieson\n              SW.\n            \n          \n          Translocation of the aortic valve for prosthetic valve endocarditis.\n\t\t\t\t\tJ Thorac Cardiovasc Surg1981;81(2):212\u20138."},{"issue":"1","key":"i1526-6702-47-4-280-b10","series-title":"Ann Thorac Surg","first-page":"1","article-title":"Surgical management of left ventricular-aortic discontinuity complicating bacterial endocarditis","volume":"29","year":"1980","unstructured":"Frantz\n              PT,\n            \n            \n              Murray\n              GF,\n            \n            \n              Wilcox\n              BR.\n            \n          \n          Surgical management of left ventricular-aortic discontinuity complicating bacterial endocarditis.\n\t\t\t\t\tAnn Thorac Surg1980;29(1):1\u20137."},{"issue":"2","key":"i1526-6702-47-4-280-b11","series-title":"Ann Thorac Surg","first-page":"148","article-title":"Successful management of aortic valve endocarditis with associated periannular abscess and aneurysm","volume":"42","year":"1986","unstructured":"VanHooser\n              DW,\n            \n            \n              Johnson\n              RG,\n            \n            \n              Hein\n              RA,\n            \n            \n              Elkins\n              RC.\n            \n          \n          Successful management of aortic valve endocarditis with associated periannular abscess and aneurysm.\n\t\t\t\t\tAnn Thorac Surg1986;42(2):148\u201351."},{"issue":"5","key":"i1526-6702-47-4-280-b12","series-title":"J Am Coll Cardiol","first-page":"1177","article-title":"Treatment of complicated prosthetic aortic valve endocarditis with annular abscess formation by homograft aortic root replacement","volume":"17","year":"1991","unstructured":"Glazier\n              JJ,\n            \n            \n              Verwilghen\n              J,\n            \n            \n              Donaldson\n              RM,\n            \n            \n              Ross\n              DN.\n            \n          \n          Treatment of complicated prosthetic aortic valve endocarditis with annular abscess formation by homograft aortic root replacement.\n\t\t\t\t\tJ Am Coll Cardiol1991;17(5):1177\u201382."},{"issue":"2","key":"i1526-6702-47-4-280-b13","series-title":"J Thorac Cardiovasc Surg","first-page":"291","article-title":"Acute endocarditis: surgical treatment of aortic regurgitation and aortico-left ventricular discontinuity","volume":"84","year":"1982","unstructured":"Symbas\n              PN,\n            \n            \n              Vlasis\n              SE,\n            \n            \n              Zacharopoulos\n              L,\n            \n            \n              Lutz\n              JF.\n            \n          \n          Acute endocarditis: surgical treatment of aortic regurgitation and aortico-left ventricular discontinuity.\n\t\t\t\t\tJ Thorac Cardiovasc Surg1982;84(2):291\u20136."},{"issue":"5","key":"i1526-6702-47-4-280-b14","series-title":"Ann Thorac Surg","first-page":"1486","article-title":"Aortic valve translocation for severe prosthetic valve endocarditis: early results and long-term follow-up","volume":"79","year":"2005","unstructured":"Nottin\n              R,\n            \n            \n              Al-Attar\n              N,\n            \n            \n              Ramadan\n              R,\n            \n            \n              Azmoun\n              A,\n            \n            \n              Therasse\n              A,\n            \n            \n              Kortas\n              C,\n            \n          \n          .\n\t\t\t\t\tAortic valve translocation for severe prosthetic valve endocarditis: early results and long-term follow-up.\n\t\t\t\t\tAnn Thorac Surg2005;79(5):1486\u201390."},{"issue":"7","key":"i1526-6702-47-4-280-b15","series-title":"Heart Lung Circ","first-page":"1112","article-title":"Surgery for active infective endocarditis of the aortic valve with infection extending beyond the leaflets","volume":"28","year":"2019","unstructured":"Elgalad\n              A,\n            \n            \n              Arafat\n              A,\n            \n            \n              Elshazly\n              T,\n            \n            \n              Elkahwagy\n              M,\n            \n            \n              Fawzy\n              H,\n           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Journal"],"original-title":[],"link":[{"URL":"https:\/\/thij.kglmeridian.com\/view\/journals\/thij\/47\/4\/article-p280.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/meridian.allenpress.com\/thij\/article-pdf\/47\/4\/280\/2778517\/i1526-6702-47-4-280.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thij.kglmeridian.com\/downloadpdf\/journals\/thij\/47\/4\/article-p280.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thij.kglmeridian.com\/downloadpdf\/journals\/thij\/47\/4\/article-p280.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,7]],"date-time":"2024-11-07T15:36:27Z","timestamp":1730993787000},"score":1,"resource":{"primary":{"URL":"https:\/\/thij.kglmeridian.com\/view\/journals\/thij\/47\/4\/article-p280.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8]]},"references-count":18,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.14503\/thij-19-7059","relation":{},"ISSN":["0730-2347","1526-6702"],"issn-type":[{"type":"print","value":"0730-2347"},{"type":"electronic","value":"1526-6702"}],"subject":[],"published":{"date-parts":[[2020,8]]}}}