{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T00:12:42Z","timestamp":1768263162901,"version":"3.49.0"},"reference-count":27,"publisher":"Texas Heart Institute Journal","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:p>Bariatric surgery helps many morbidly obese patients lose substantial weight. However, few data exist on its long-term safety and effectiveness in patients who also have continuous-flow left ventricular assist devices and in whom heart transplantation is contemplated. We retrospectively identified patients at our institution who had undergone ventricular assist device implantation and subsequent laparoscopic sleeve gastrectomy from June 2015 through September 2017, and we evaluated their baseline demographic data, preoperative characteristics, and postoperative outcomes.<\/jats:p>\n        <jats:p>Four patients (3 men), ranging in age from 32 to 44 years and in body mass index from 40 to 57, underwent sleeve gastrectomy from 858 to 1,849 days after left ventricular assist device implantation to treat nonischemic cardiomyopathy. All had multiple comorbidities.<\/jats:p>\n        <jats:p>At a median follow-up duration of 42 months (range, 24\u201347 mo), median body mass index decreased to 31.9 (range, 28.3\u201344.3) at maximal weight loss, with a median percentage of excess body mass index lost of 72.5% (range, 38.7%\u201387.4%). After achieving target weight, one patient was listed for heart transplantation, another awaited listing, one was kept on destination therapy because of positive drug screens, and one regained weight and remained ineligible.<\/jats:p>\n        <jats:p>On long-term follow-up, laparoscopic sleeve gastrectomy appears to be safe and feasible for morbidly obese patients with ventricular assist devices who must lose weight for transplantation consideration. Additional studies are warranted to evaluate this weight-loss strategy after transplantation and immunosuppression.<\/jats:p>","DOI":"10.14503\/thij-19-7161","type":"journal-article","created":{"date-parts":[[2021,1,20]],"date-time":"2021-01-20T23:30:05Z","timestamp":1611185405000},"page":"284-289","source":"Crossref","is-referenced-by-count":8,"title":["Effect of Laparoscopic Sleeve Gastrectomy on Heart Transplant Status in 4 Patients with Left Ventricular Assist Devices"],"prefix":"10.14503","volume":"47","author":[{"given":"Christopher T.","family":"Ryan","sequence":"first","affiliation":[{"name":"Division of Cardiothoracic Transplantation and Mechanical Circulatory Support, Department of Surgery; Baylor College of Medicine, Houston, Texas 77030"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adriana","family":"Santiago","sequence":"additional","affiliation":[{"name":"Division of Cardiothoracic Transplantation and Mechanical Circulatory Support, Department of Surgery; Baylor College of Medicine, Houston, Texas 77030"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nabil","family":"Tariq","sequence":"additional","affiliation":[{"name":"Bariatric and Metabolic Surgery Center, Department of Surgery; Baylor College of Medicine, Houston, Texas 77030"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harveen K.","family":"Lamba","sequence":"additional","affiliation":[{"name":"Division of Cardiothoracic Transplantation and Mechanical Circulatory Support, Department of Surgery; Baylor College of Medicine, Houston, Texas 77030"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5628","reference":[{"issue":"11","key":"i1526-6702-47-4-284-b1","series-title":"J Am Coll Cardiol","first-page":"2267","article-title":"Impact of obesity on cardiac geometry and function in a population of adolescents: the Strong Heart Study","volume":"47","year":"2006","unstructured":"Chinali\n              M,\n            \n       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Transplant2006;25(9):1024\u201342."},{"issue":"1","key":"i1526-6702-47-4-284-b7","series-title":"J Heart Lung Transplant","first-page":"1","article-title":"The 2016 International Society for Heart Lung Transplantation listing criteria for heart transplantation: a 10-year update","volume":"35","year":"2016","unstructured":"Mehra\n              MR,\n            \n            \n              Canter\n              CE,\n            \n            \n              Hannan\n              MM,\n            \n            \n              Semigran\n              MJ,\n            \n            \n              Uber\n              PA,\n            \n            \n              Baran\n              DA,\n            \n          \n          .\n\t\t\t\t\tThe 2016 International Society for Heart Lung Transplantation listing criteria for heart transplantation: a 10-year update.\n\t\t\t\t\tJ Heart Lung Transplant2016;35(1):1\u201323."},{"issue":"10","key":"i1526-6702-47-4-284-b8","series-title":"J Heart Lung Transplant","first-page":"1066","article-title":"Drive-line infections and sepsis in patients receiving the HVAD system as a left ventricular assist device","volume":"33","year":"2014","unstructured":"John\n              R,\n            \n            \n              Aaronson\n              KD,\n            \n            \n              Pae\n              WE,\n            \n            \n              Acker\n              MA,\n            \n            \n              Hathaway\n              DR,\n            \n            \n              Najarian\n              KB,\n            \n          \n          .\n\t\t\t\t\tDrive-line infections and sepsis in patients receiving the HVAD system as a left ventricular assist device.\n\t\t\t\t\tJ Heart Lung Transplant2014;33(10):1066\u201373."},{"issue":"5","key":"i1526-6702-47-4-284-b9","series-title":"Curr Opin Hematol","first-page":"437","article-title":"Mechanisms of thrombosis in obesity","volume":"20","year":"2013","unstructured":"Blokhin\n              IO,\n            \n            \n              Lentz\n              SR.\n            \n          \n          Mechanisms of thrombosis in obesity.\n\t\t\t\t\tCurr Opin Hematol2013;20(5):437\u201344."},{"issue":"2","key":"i1526-6702-47-4-284-b10","series-title":"Thromb Res","first-page":"346","article-title":"The prothrombotic paradox of severe obesity after cardiac surgery under cardiopulmonary bypass","volume":"134","year":"2014","unstructured":"Kindo\n              M,\n            \n            \n              Minh\n              TH,\n            \n            \n              Gerelli\n              S,\n            \n            \n              Meyer\n              N,\n            \n            \n              Schaeffer\n              M,\n            \n            \n              Perrier\n              S,\n            \n          \n          .\n\t\t\t\t\tThe prothrombotic paradox of severe obesity after cardiac surgery under cardiopulmonary bypass.\n\t\t\t\t\tThromb Res2014;134(2):346\u201353."},{"issue":"6","key":"i1526-6702-47-4-284-b11","series-title":"ESC Heart Fail","first-page":"1141","article-title":"Left ventricular assist device implantation improves glycaemic control: a systematic review and meta-analysis","volume":"5","year":"2018","unstructured":"Patel\n              N,\n            \n            \n              Gluck\n              JA,\n            \n            \n              Radojevic\n              J,\n            \n            \n              Coleman\n              CI,\n            \n            \n              Baker\n              WL.\n            \n          \n          Left ventricular assist device implantation improves glycaemic control: a systematic review and meta-analysis.\n\t\t\t\t\tESC Heart Fail2018;5(6):1141\u20139."},{"issue":"2","key":"i1526-6702-47-4-284-b12","series-title":"Circ J","first-page":"213","article-title":"Higher body mass index increases risk of HeartMate II pump thrombosis but does not adversely affect long-term survival","volume":"81","year":"2017","unstructured":"Han\n              JJ,\n            \n            \n              Sooppan\n              R,\n            \n            \n              Johnson\n              AP,\n            \n            \n              Chen\n              CW,\n            \n            \n              Gaffey\n              AC,\n            \n            \n              Phillips\n              EC,\n            \n          \n          .\n\t\t\t\t\tHigher body mass index increases risk of HeartMate II pump thrombosis but does not adversely affect long-term survival.\n\t\t\t\t\tCirc J2017;81(2):213\u20139."},{"issue":"3","key":"i1526-6702-47-4-284-b13","series-title":"JAMA Surg","first-page":"275","article-title":"Bariatric surgery: an updated systematic review and meta-analysis","volume":"149","year":"2014","unstructured":"Chang\n              SH,\n            \n            \n              Stoll\n              CRT,\n            \n            \n      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Available from: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK453378\/."},{"issue":"1","key":"i1526-6702-47-4-284-b15","series-title":"J Heart Lung Transplant","first-page":"31","article-title":"Patients with low compared with high body mass index gain more weight after implantation of a continuous-flow left ventricular assist device","volume":"32","year":"2013","unstructured":"Emani\n              S,\n            \n            \n              Brewer\n              RJ,\n            \n            \n              John\n              R,\n            \n            \n              Slaughter\n              MS,\n            \n            \n              Lanfear\n              DE,\n            \n            \n              Ravi\n              Y,\n            \n          \n          .\n\t\t\t\t\tPatients with low compared with high body mass index gain more weight after implantation of a continuous-flow left ventricular assist device.\n\t\t\t\t\tJ Heart Lung Transplant2013;32(1):31\u20135."},{"issue":"8 Suppl","key":"i1526-6702-47-4-284-b16","series-title":"J Card Fail","first-page":"S47","article-title":"LVAD support as a bridge to transplant in the morbidly obese needs a long-term weight loss strategy","volume":"16","year":"2010","unstructured":"Jones\n              WL,\n            \n            \n              Garcia\n              LJ,\n            \n            \n              Trevino\n              AR,\n            \n            \n              Bruckner\n              BA,\n            \n            \n              Loebe\n              M,\n            \n            \n              Noon\n              GP,\n            \n          \n          .\n\t\t\t\t\tLVAD support as a bridge to transplant in the morbidly obese needs a long-term weight loss strategy.\n\t\t\t\t\tJ Card Fail2010;16(8 Suppl):S47."},{"issue":"4 Suppl","key":"i1526-6702-47-4-284-b17","series-title":"J Heart Lung Transplant","first-page":"S162","article-title":"Temporal trends in body mass index after implantation with continuous flow LVAD [abstract]","volume":"30","year":"2011","unstructured":"Toma\n              M,\n            \n            \n              Dorogi\n              A,\n            \n            \n              Gonzalez-Stawinski\n              GV,\n            \n            \n              Smedira\n              NG,\n            \n            \n              Starling\n              RC,\n            \n            \n              Mountis\n              MM.\n            \n          \n          Temporal trends in body mass index after implantation with continuous flow LVAD [abstract].\n\t\t\t\t\tJ Heart Lung Transplant2011;30(4 Suppl):S162."},{"issue":"5","key":"i1526-6702-47-4-284-b18","series-title":"Obes Surg","first-page":"1030","article-title":"The effects of bariatric surgery on cardiac structure and function: a systematic review of cardiac imaging outcomes","volume":"26","year":"2016","unstructured":"Aggarwal\n              R,\n            \n            \n              Harling\n              L,\n            \n            \n              Efthimiou\n              E,\n            \n            \n              Darzi\n              A,\n            \n            \n              Athanasiou\n              T,\n            \n            \n              Ashrafian\n              H.\n            \n          \n          The effects of bariatric surgery on cardiac structure and function: a systematic review of cardiac imaging outcomes.\n\t\t\t\t\tObes Surg2016;26(5):1030\u201340."},{"issue":"6","key":"i1526-6702-47-4-284-b19","series-title":"Am J Surg","first-page":"903","article-title":"Is laparoscopic sleeve gastrectomy a lower risk bariatric procedure compared with laparoscopic Roux-en-Y gastric bypass? A meta-analysis","volume":"208","year":"2014","unstructured":"Zellmer\n              JD,\n            \n            \n              Mathiason\n              MA,\n            \n            \n              Kallies\n              KJ,\n            \n            \n              Kothari\n              SN.\n            \n          \n          Is laparoscopic sleeve gastrectomy a lower risk bariatric procedure compared with laparoscopic Roux-en-Y gastric bypass? A meta-analysis.\n\t\t\t\t\tAm J Surg2014;208(6):903\u201310."},{"issue":"5","key":"i1526-6702-47-4-284-b20","series-title":"Am J Med","first-page":"517","article-title":"Oral anticoagulant use after bariatric surgery: a literature review and clinical guidance","volume":"130","year":"2017","unstructured":"Martin\n              KA,\n            \n            \n              Lee\n              CR,\n            \n            \n              Farrell\n              TM,\n            \n            \n              Moll\n              S.\n            \n          \n          Oral anticoagulant use after bariatric surgery: a literature review and clinical guidance.\n\t\t\t\t\tAm J Med2017;130(5):517\u201324."},{"issue":"3","key":"i1526-6702-47-4-284-b21","series-title":"JSLS","article-title":"Sleeve gastrectomy and left ventricular assist device for heart transplant","volume":"21","year":"2017","unstructured":"Greene\n              J,\n            \n            \n              Tran\n              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weight, patient satisfaction, comorbidities, and gastroesophageal reflux treatment after laparoscopic sleeve gastrectomy.\n\t\t\t\t\tSurg Obes Relat Dis2016;12(10):1778\u201386."},{"issue":"1","key":"i1526-6702-47-4-284-b23","series-title":"Surg Obes Relat Dis","first-page":"88","article-title":"Laparoscopic sleeve gastrectomy in morbidly obese patients with end-stage heart failure and left ventricular assist device: medium-term results","volume":"11","year":"2015","unstructured":"Chaudhry\n              UI,\n            \n            \n              Kanji\n              A,\n            \n            \n              Sai-Sudhakar\n              CB,\n            \n            \n              Higgins\n              RS,\n            \n            \n              Needleman\n              BJ.\n            \n          \n          Laparoscopic sleeve gastrectomy in morbidly obese patients with end-stage heart failure and left ventricular assist device: medium-term results.\n\t\t\t\t\tSurg Obes Relat Dis2015;11(1):88\u201393."},{"issue":"9","key":"i1526-6702-47-4-284-b24","series-title":"Surg Obes Relat Dis","first-page":"1269","article-title":"Laparoscopic sleeve gastrectomy in patients with heart failure and left ventricular assist devices as a bridge to transplant","volume":"14","year":"2018","unstructured":"Hawkins\n              RB,\n            \n            \n              Go\n              K,\n            \n            \n              Raymond\n              SL,\n            \n            \n              Ayzengart\n              A,\n            \n            \n              Friedman\n              J.\n            \n          \n          Laparoscopic sleeve gastrectomy in patients with heart failure and left ventricular assist devices as a bridge to transplant.\n\t\t\t\t\tSurg Obes Relat Dis2018;14(9):1269\u201373."},{"issue":"3","key":"i1526-6702-47-4-284-b25","series-title":"Surg Obes Relat Dis","first-page":"479","article-title":"Bariatric surgery: a safe and effective conduit to cardiac transplantation","volume":"10","year":"2014","unstructured":"Wikiel\n              KJ,\n            \n            \n              McCloskey\n              CA,\n            \n            \n              Ramanathan\n              RC.\n            \n          \n          Bariatric surgery: a safe and effective conduit to cardiac transplantation.\n\t\t\t\t\tSurg Obes Relat Dis2014;10(3):479\u201384."},{"issue":"11","key":"i1526-6702-47-4-284-b26","series-title":"J Heart Lung Transplant","first-page":"1489","article-title":"Simultaneous left ventricular assist device placement and laparoscopic sleeve gastrectomy as a bridge to transplant for morbidly obese patients with severe heart failure","volume":"34","year":"2015","unstructured":"Shah\n              SK,\n            \n            \n              Gregoric\n              ID,\n            \n            \n              Nathan\n              SS,\n            \n            \n              Akkanti\n              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         Laparoscopic gastric bypass during left ventricular assist device support and ventricular recovery.\n\t\t\t\t\tJ Heart Lung Transplant2014;33(8):870\u20131."}],"container-title":["Texas Heart Institute 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