{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T02:21:31Z","timestamp":1780539691560,"version":"3.54.1"},"reference-count":31,"publisher":"Texas Heart Institute Journal","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:p>Myocardial injury (MI) is not unusual after transcatheter aortic valve replacement (TAVR). To determine precipitating factors and prognostic outcomes of MI after TAVR, we retrospectively investigated relationships between MI after TAVR and aortic root dimensions, baseline patient characteristics, echocardiographic findings, and procedural features.<\/jats:p>\n        <jats:p>Of 474 patients who underwent transfemoral TAVR for severe aortic stenosis in our tertiary center from June 2011 through June 2018, 188 (mean age, 77.7 \u00b1 7.7 yr; 96 women [51%]) met the study inclusion criteria. Patients were divided into postprocedural MI (PMI) (n=74) and no-PMI (n=114) groups, in accordance with high-sensitivity troponin T levels.<\/jats:p>\n        <jats:p>We found that MI risk was associated with older age (odds ratio [OR]=1.054; 95% CI, 1.013\u20131.098; <jats:italic>P<\/jats:italic>=0.01), transcatheter heart valve type (OR=10.207; 95% CI, 2.861\u201336.463; <jats:italic>P<\/jats:italic>=0.001), distances from the aortic annulus to the right coronary artery ostium (OR=0.853; 95% CI, 0.731\u20130.995; <jats:italic>P<\/jats:italic>=0.04) and the left main coronary artery ostium (OR=0.747; 95% CI, 0.616\u20130.906; <jats:italic>P<\/jats:italic>=0.003), and baseline glomerular filtration rate (OR=0.985; 95% CI, 0.970\u20131.000; <jats:italic>P<\/jats:italic>=0.04). Moreover, the PMI group had a longer time to hospital discharge (<jats:italic>P<\/jats:italic>=0.001) and a higher permanent pacemaker implantation rate (<jats:italic>P<\/jats:italic>=0.04) than did the no-PMI group.<\/jats:p>\n        <jats:p>Our findings may enable better estimation of which patients are at higher risk of MI after TAVR and thus improve the planning and course of clinical care.<\/jats:p>","DOI":"10.14503\/thij-20-7380","type":"journal-article","created":{"date-parts":[[2022,7,15]],"date-time":"2022-07-15T14:07:48Z","timestamp":1657894068000},"source":"Crossref","is-referenced-by-count":2,"title":["Predictors and Prognostic Implications of Myocardial Injury After Transcatheter Aortic Valve Replacement"],"prefix":"10.14503","volume":"49","author":[{"given":"Murat Can","family":"Guney","sequence":"first","affiliation":[{"name":"Department of Cardiology, Faculty of Medicine, Ankara Yildirim Beyazit University, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Telat","family":"Keles","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Faculty of Medicine, Ankara Yildirim Beyazit University, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bilge Duran","family":"Karaduman","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Faculty of Medicine, Atilim University, Medicana International Ankara Hospital, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huseyin","family":"Ayhan","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Faculty of Medicine, Atilim University, Medicana International Ankara Hospital, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hakan","family":"Suygun","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Faculty of Medicine, Ankara Yildirim Beyazit University, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muzaffer","family":"Kahyaoglu","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Gaziantep Abdulkadir Yuksel State Hospital, Gaziantep, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Engin","family":"Bozkurt","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Faculty of Medicine, Ankara Yildirim Beyazit University, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5628","reference":[{"issue":"1 Suppl","key":"i1526-6702-49-4-e207380-b1","series-title":"Circulation","first-page":"61","article-title":"Aortic stenosis","volume":"38","year":"1968","unstructured":"Ross\n              J\n              Jr,\n            \n            \n              Braunwald\n              E.\n            \n          \n          Aortic stenosis.\n\t\t\t\t\tCirculation1968;38(1 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Interv","first-page":"e006664","article-title":"Current Society of Thoracic Surgeons model reclassifies mortality risk in patients undergoing transcatheter aortic valve replacement","volume":"11","year":"2018","unstructured":"Kumar\n              A,\n            \n            \n              Sato\n              K,\n            \n            \n              Narayanswami\n              J,\n            \n            \n              Banerjee\n              K,\n            \n            \n              Andress\n              K,\n            \n            \n              Lokhande\n              C,\n            \n          \n          .\n\t\t\t\t\tCurrent Society of Thoracic Surgeons model reclassifies mortality risk in patients undergoing transcatheter aortic valve replacement.\n\t\t\t\t\tCirc Cardiovasc Interv2018;11(9):e006664."},{"issue":"25","key":"i1526-6702-49-4-e207380-b11","series-title":"Circulation","first-page":"e1159","article-title":"2017 AHA\/ACC focused update of the 2014 AHA\/ACC guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology\/American Heart Association Task Force on Clinical Practice Guidelines","volume":"135","year":"2017","unstructured":"Nishimura\n              RA,\n            \n            \n              Otto\n              CM,\n            \n            \n              Bonow\n              RO,\n            \n            \n              Carabello\n              BA,\n            \n            \n              Erwin\n              JP\n              3rd,\n            \n            \n              Fleisher\n              LA,\n            \n          \n          .\n\t\t\t\t\t2017 AHA\/ACC focused update of the 2014 AHA\/ACC guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology\/American Heart Association Task Force on Clinical Practice Guidelines.\n\t\t\t\t\tCirculation2017;135(25):e1159\u201395."},{"issue":"9","key":"i1526-6702-49-4-e207380-b12","series-title":"Am J Cardiol","first-page":"1337","article-title":"Prevalence and effect of myocardial injury after transcatheter aortic valve replacement","volume":"111","year":"2013","unstructured":"Barbash\n              IM,\n            \n            \n              Dvir\n              D,\n            \n            \n              Ben-Dor\n              I,\n            \n            \n              Badr\n              S,\n            \n            \n              Okubagzi\n              P,\n            \n            \n              Torguson\n              R,\n            \n          \n          .\n\t\t\t\t\tPrevalence and effect of myocardial injury after transcatheter aortic valve replacement.\n\t\t\t\t\tAm J Cardiol2013;111(9):1337\u201343."},{"issue":"22","key":"i1526-6702-49-4-e207380-b13","series-title":"J Am Coll Cardiol","first-page":"2173","article-title":"Universal definition of myocardial infarction","volume":"50","year":"2007","unstructured":"Thygesen\n              K,\n            \n            \n              Alpert\n              JS,\n            \n            \n              White\n              HD;\n            \n            Joint ESC\/ACCF\/AHA\/WHF Task Force for the Redefinition of Myocardial Infarction.\n\t\t\t\t\t\n          Universal definition of myocardial infarction.\n\t\t\t\t\tJ Am Coll Cardiol2007;50(22):2173\u201395."},{"issue":"5","key":"i1526-6702-49-4-e207380-b14","series-title":"Clin Res Cardiol","first-page":"379","article-title":"Myocardial injury associated with transcatheter aortic valve implantation (TAVI)","volume":"105","year":"2016","unstructured":"Kim\n              WK,\n            \n            \n              Liebetrau\n              C,\n            \n            \n              van Linden\n              A,\n            \n            \n              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   \n          Prognostic value of myocardial injury following transcatheter aortic valve implantation.\n\t\t\t\t\tAm J Cardiol2013;111(10):1475\u201381."},{"issue":"3","key":"i1526-6702-49-4-e207380-b28","series-title":"Circ Cardiovasc Interv","first-page":"415","article-title":"Predictors and prognostic value of myocardial injury during transcatheter aortic valve implantation","volume":"5","year":"2012","unstructured":"Yong\n              ZY,\n            \n            \n              Wiegerinck\n              EMA,\n            \n            \n              Boerlage-van Dijk\n              K,\n            \n            \n              Koch\n              KT,\n            \n            \n              Vis\n              MM,\n            \n            \n              Bouma\n              BJ,\n            \n          \n          .\n\t\t\t\t\tPredictors and prognostic value of myocardial injury during transcatheter aortic valve implantation.\n\t\t\t\t\tCirc Cardiovasc Interv2012;5(3):415\u201323."},{"issue":"19","key":"i1526-6702-49-4-e207380-b29","series-title":"J Am Coll Cardiol","first-page":"2075","article-title":"Predictors and impact of myocardial injury after transcatheter aortic valve replacement: a multicenter registry","volume":"66","year":"2015","unstructured":"Ribeiro\n              HB,\n            \n            \n              Nombela-Franco\n              L,\n            \n            \n              Mu\u00f1oz-Garc\u00eda\n              AJ,\n            \n            \n              Lemos\n              PA,\n            \n            \n              Amat-Santos\n              I,\n            \n            \n              Serra\n              V,\n            \n          \n          .\n\t\t\t\t\tPredictors and impact of myocardial injury after transcatheter aortic valve replacement: a multicenter registry.\n\t\t\t\t\tJ Am Coll Cardiol2015;66(19):2075\u201388."},{"issue":"11","key":"i1526-6702-49-4-e207380-b30","series-title":"Circ Cardiovasc Interv","first-page":"e007106","article-title":"Periprocedural myocardial injury predicts short- and long-term mortality in patients undergoing transcatheter aortic valve replacement","volume":"11","year":"2018","unstructured":"Michail\n              M,\n            \n            \n              Cameron\n              JN,\n            \n            \n              Nerlekar\n              N,\n            \n            \n              Ihdayhid\n              AR,\n            \n            \n              McCormick\n              LM,\n            \n            \n              Gooley\n              R,\n            \n          \n          .\n\t\t\t\t\tPeriprocedural myocardial injury predicts short- and long-term mortality in patients undergoing transcatheter aortic valve replacement.\n\t\t\t\t\tCirc Cardiovasc Interv2018;11(11):e007106."},{"issue":"8","key":"i1526-6702-49-4-e207380-b31","series-title":"Eur Heart J","first-page":"988","article-title":"Early diagnosis of acute myocardial infarction in patients with pre-existing coronary artery disease using more sensitive cardiac troponin assays","volume":"33","year":"2012","unstructured":"Reiter\n              M,\n            \n            \n              Twerenbold\n              R,\n            \n            \n              Reichlin\n              T,\n            \n            \n              Benz\n              B,\n            \n            \n              Haaf\n              P,\n            \n            \n              Meissner\n              J,\n            \n          \n          .\n\t\t\t\t\tEarly diagnosis of acute myocardial infarction in patients with pre-existing coronary artery disease using more sensitive cardiac troponin assays.\n\t\t\t\t\tEur Heart J2012;33(8):988\u201397."}],"container-title":["Texas Heart Institute 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