{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T02:04:49Z","timestamp":1780970689103,"version":"3.54.1"},"reference-count":27,"publisher":"Texas Heart Institute Journal","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,9,1]]},"abstract":"\n Background<\/jats:title>\n Neoaortic sinus dilatation is a late comorbidity after an arterial switch operation in patients with dextro-transposition of the great arteries. We aim to explore whether neoaortic sinus dilatation is related to overweight or obesity, as these affect aortic remodeling in such patients.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n We measured neoaortic diameters including those for the annulus, sinus, sinotubular junction, and ascending aorta by echocardiography and studied the relationship between these diameters and body mass index in patients aged 15 years and older after an arterial switch operation.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n A total of 45 patients were studied. Median (interquartile range) age, body mass index, and systolic blood pressure at echocardiography were 20 (17\u201328) years, 21.2 (18.4\u201324.2) kg\/m2<\/jats:sup>, and 120 (112\u2013127) mm Hg, respectively. Echocardiogram revealed the following median values (interquartile ranges): neoaortic annulus diameter, 22.2 (19.8\u201323.8) mm; sinus diameter, 34.6 (31.8\u201339.8) mm; sinotubular junction diameter, 27.5 (22.4\u201330.0) mm; and ascending aortic diameter, 20.4 (19.4\u201322.7) mm. The neoaortic sinus diameter was significantly correlated with body mass index (r<\/jats:italic> = 0.41, P<\/jats:italic> = .004) and was significantly larger in patients with concomitant ventricular septal defect (P<\/jats:italic> < .001) and those who were over-weight (body mass index \u226525 kg\/m2<\/jats:sup>; P<\/jats:italic> = .006).<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Neoaortic sinus dilatation after an arterial switch operation is associated with being overweight during adolescence and young adulthood. It is important to prevent obesity in patients after an arterial switch operation and educate them on a healthy lifestyle.<\/jats:p>\n <\/jats:sec>","DOI":"10.14503\/thij-20-7508","type":"journal-article","created":{"date-parts":[[2022,10,19]],"date-time":"2022-10-19T14:22:29Z","timestamp":1666189349000},"source":"Crossref","is-referenced-by-count":1,"title":["Being Overweight Is Related to Neoaortic Sinus Dilatation After Arterial Switch Operation"],"prefix":"10.14503","volume":"49","author":[{"given":"Jun","family":"Muneuchi","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Kyushu Hospital, Japan Community Healthcare Organization, Kitakyushu, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mamie","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Kyushu Hospital, Japan Community Healthcare Organization, Kitakyushu, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuichiro","family":"Sugitani","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Kyushu Hospital, Japan Community Healthcare Organization, Kitakyushu, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirohito","family":"Doi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Kyushu Hospital, Japan Community Healthcare Organization, Kitakyushu, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Furuta","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Kyushu Hospital, Japan Community Healthcare Organization, Kitakyushu, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroki","family":"Ezaki","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Kyushu Hospital, Japan Community Healthcare Organization, Kitakyushu, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaru","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Kyushu Hospital, Japan Community Healthcare Organization, Kitakyushu, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshie","family":"Ochiai","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Kyushu Hospital, Japan Community Healthcare Organization, Kitakyushu, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5628","reference":[{"issue":"1","key":"i1526-6702-49-5-e207508-b1","series-title":"J Am Coll Cardiol.","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/j.jacc.2016.10.051","article-title":"Transposition of the great arteries in the developing world: surgery and outcomes","volume":"69","year":"2017","unstructured":"Schidlow\n DN,\n \n \n Jenkins\n KJ,\n \n \n Gauvreau\n K,\n \n \n .\n\t\t\t\t\tTransposition of the great arteries in the developing world: surgery and outcomes.\n\t\t\t\t\tJ Am Coll Cardiol.2017;69(1):43\u201351.\n\t\t\t\t\tdoi:10.1016\/j.jacc.2016.10.051"},{"issue":"3\u20134","key":"i1526-6702-49-5-e207508-b2","series-title":"Prog Cardiovasc Dis.","doi-asserted-by":"publisher","first-page":"360","DOI":"10.1016\/j.pcad.2018.08.007","article-title":"Long-term outcomes of the arterial switch operation for d-transposition of the great arteries","volume":"61","year":"2018","unstructured":"Moe\n TG,\n \n \n Bardo\n DME.\n \n \n Long-term outcomes of the arterial switch operation for d-transposition of the great arteries.\n\t\t\t\t\tProg Cardiovasc Dis.2018;61(3\u20134):360\u2013364.\n\t\t\t\t\tdoi:10.1016\/j.pcad.2018.08.007"},{"issue":"22","key":"i1526-6702-49-5-e207508-b3","series-title":"Heart.","doi-asserted-by":"publisher","first-page":"1732","DOI":"10.1136\/heartjnl-2019-315157","article-title":"Progression of aortic root dilatation and aortic valve regurgitation after the arterial switch operation","volume":"105","year":"2019","unstructured":"van der Palen\n RLF,\n \n \n van der Bom\n T,\n \n \n Dekker\n A,\n \n \n .\n\t\t\t\t\tProgression of aortic root dilatation and aortic valve regurgitation after the arterial switch operation.\n\t\t\t\t\tHeart.2019;105(22):1732\u20131740.\n\t\t\t\t\tdoi:10.1136\/heartjnl-2019-315157"},{"issue":"3","key":"i1526-6702-49-5-e207508-b4","series-title":"Circulation.","doi-asserted-by":"publisher","first-page":"734","DOI":"10.1161\/01.cir.91.3.734","article-title":"Determinants of echocardiographic aortic root size. 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2013.\n\t\t\t\t\tLancet.2014;384(9945):766\u2013781.\n\t\t\t\t\tdoi:10.1016\/S0140-6736(14)60460-8"},{"issue":"9","key":"i1526-6702-49-5-e207508-b12","series-title":"J Am Soc Echocardiogr.","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1016\/j.echo.2016.04.006","article-title":"Multimodality assessment of ascending aortic diameters: comparison of different measurement methods","volume":"29","year":"2016","unstructured":"Rodr\u00edguez-Palomares\n JF,\n \n \n Teixid\u00f3-Tura\n G,\n \n \n Galuppo\n V,\n \n \n .\n\t\t\t\t\tMultimodality assessment of ascending aortic diameters: comparison of different measurement methods.\n\t\t\t\t\tJ Am Soc Echocardiogr.2016;29(9):819\u2013826.\n\t\t\t\t\tdoi:10.1016\/j.echo.2016.04.006"},{"issue":"3","key":"i1526-6702-49-5-e207508-b13","series-title":"Circulation.","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1161\/01.cir.103.3.393","article-title":"Structural abnormalities of great arterial walls in congenital heart 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Society of Thoracic Surgeons, and Society for Vascular Medicine","volume":"121","year":"2010","unstructured":"Hiratzka\n LF,\n \n \n Bakris\n GL,\n \n \n Beckman\n JA,\n \n ;\n\t\t\t\t\t\tAmerican College of Cardiology Foundation\/American Heart Association Task Force on Practice Guidelines, American Association for Thoracic Surgery, American College of Radiology,.\n\t\t\t\t\t\n 2010 ACCF\/AHA\/AATS\/ACR\/ASA\/SCA\/SCAI\/SIR\/STS\/SVM Guidelines for the diagnosis and management of patients with thoracic aortic disease: a report of the American College of Cardiology Foundation\/American Heart Association Task Force on Practice Guidelines, American Association for Thoracic Surgery, American College of Radiology, American Stroke Association, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society of Interventional Radiology, Society of Thoracic Surgeons, and Society for Vascular Medicine.\n\t\t\t\t\tJ Am Coll Cardiol.2010;121(13):e266\u2013e369.\n\t\t\t\t\tdoi:10.1161\/cir.0b013e3181d4739e"},{"issue":"14","key":"i1526-6702-49-5-e207508-b27","series-title":"Circulation.","doi-asserted-by":"publisher","first-page":"e698","DOI":"10.1161\/CIR.0000000000000603","article-title":"2018 AHA\/ACC guideline for the management of adults with congenital heart disease: a report of the American College of Cardiology\/American Heart Association Task Force on Clinical Practice Guidelines","volume":"139","year":"2019","unstructured":"Stout\n KK,\n \n \n Daniels\n CJ,\n \n \n Aboulhosn\n JA,\n \n \n .\n\t\t\t\t\t2018 AHA\/ACC guideline for the management of adults with congenital heart disease: a report of the American College of Cardiology\/American Heart Association Task Force on Clinical Practice Guidelines.\n\t\t\t\t\tCirculation.2019;139(14):e698\u2013e800.\n\t\t\t\t\tdoi:10.1161\/CIR.0000000000000603"}],"container-title":["Texas Heart Institute 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