{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T05:23:47Z","timestamp":1731043427096,"version":"3.28.0"},"reference-count":31,"publisher":"Texas Heart Institute Journal","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,9,1]]},"abstract":"<jats:sec>\n          <jats:title>Background<\/jats:title>\n          <jats:p>There are limited data on the outcomes of acute myocardial infarction\u2013cardiogenic shock (AMI-CS) in patients with concomitant cancer.<\/jats:p>\n        <\/jats:sec>\n        <jats:sec>\n          <jats:title>Methods<\/jats:title>\n          <jats:p>A retrospective cohort of adult AMI-CS admissions was identified from the National Inpatient Sample (2000\u20132017) and stratified by active cancer, historical cancer, and no cancer. Outcomes of interest included in-hospital mortality, use of coronary angiography, use of percutaneous coronary intervention, do-not-resuscitate status, palliative care use, hospitalization costs, and hospital length of stay.<\/jats:p>\n        <\/jats:sec>\n        <jats:sec>\n          <jats:title>Results<\/jats:title>\n          <jats:p>Of the 557,974 AMI-CS admissions during this 18-year period, active and historical cancers were noted in 14,826 (2.6%) and 27,073 (4.8%), respectively. From 2000 to 2017, there was a decline in active cancers (adjusted odds ratio, 0.70 [95% CI, 0.63\u20130.79]; <jats:italic>P<\/jats:italic> &lt; .001) and an increase in historical cancer (adjusted odds ratio, 2.06 [95% CI, 1.89\u20132.25]; <jats:italic>P<\/jats:italic> &lt; .001). Compared with patients with no cancer, patients with active and historical cancer received less-frequent coronary angiography (57%, 67%, and 70%, respectively) and percutaneous coronary intervention (40%, 47%, and 49%%, respectively) and had higher do-not-resuscitate status (13%, 15%, 7%%, respectively) and palliative care use (12%, 10%, 6%%, respectively) (<jats:italic>P<\/jats:italic> &lt; .001). Compared with those without cancer, higher in-hospital mortality was found in admissions with active cancer (45.9% vs 37.0%; adjusted odds ratio, 1.29 [95% CI, 1.24\u20131.34]; <jats:italic>P<\/jats:italic> &lt; .001) but not historical cancer (40.1% vs 37.0%; adjusted odds ratio, 1.01 [95% CI, 0.98\u20131.04]; <jats:italic>P<\/jats:italic> = .39). AMI-CS admissions with cancer had a shorter hospitalization duration and lower costs (all <jats:italic>P<\/jats:italic> &lt; .001).<\/jats:p>\n        <\/jats:sec>\n        <jats:sec>\n          <jats:title>Conclusion<\/jats:title>\n          <jats:p>Concomitant cancer was associated with less use of guideline-directed procedures. Active, but not historical, cancer was associated with higher mortality in patients with AMI-CS.<\/jats:p>\n        <\/jats:sec>","DOI":"10.14503\/thij-21-7598","type":"journal-article","created":{"date-parts":[[2022,10,12]],"date-time":"2022-10-12T16:15:50Z","timestamp":1665591350000},"source":"Crossref","is-referenced-by-count":0,"title":["Impact of Active and Historical Cancers on the Management and Outcomes of Acute Myocardial Infarction Complicating Cardiogenic Shock"],"prefix":"10.14503","volume":"49","author":[{"given":"Sri Harsha","family":"Patlolla","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anusha G.","family":"Bhat","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, University of Maryland, Baltimore"},{"name":"Department of Public Health Practice, School of Public Health and Health Sciences, University of Massachusetts, Amherst"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pranathi R.","family":"Sundaragiri","sequence":"additional","affiliation":[{"name":"Department of Primary Care Internal Medicine, Wake Forest Baptist Health, High Point, North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wisit","family":"Cheungpasitporn","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajkumar P.","family":"Doshi","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Nevada School of Medicine, Reno, Nevada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sudeep K.","family":"Siddappa Malleshappa","sequence":"additional","affiliation":[{"name":"Division of Hematology\/Oncology, Department of Medicine, University of Massachusetts Medical School-Baystate, Springfield, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deepak K.","family":"Pasupula","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Mercy One Medical Center, Des Moines, Iowa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wissam A.","family":"Jaber","sequence":"additional","affiliation":[{"name":"Section of Interventional Cardiology, Division of Cardiovascular Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William J.","family":"Nicholson","sequence":"additional","affiliation":[{"name":"Section of Interventional Cardiology, Division of Cardiovascular Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saraschandra","family":"Vallabhajosyula","sequence":"additional","affiliation":[{"name":"Section of Interventional Cardiology, Division of Cardiovascular Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia"},{"name":"Section of Cardiovascular Medicine, Department of Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5628","reference":[{"issue":"10","key":"i1526-6702-49-5-e217598-b1","series-title":"Eur J Heart Fail.","doi-asserted-by":"publisher","first-page":"1242","DOI":"10.1002\/ejhf.890","article-title":"Clinical phenotypes and outcome of patients hospitalized for acute heart failure: the ESC Heart Failure Long-Term Registry","volume":"19","year":"2017","unstructured":"Chioncel\n              O,\n            \n            \n              Mebazaa\n              A,\n            \n 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