{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,11,16]],"date-time":"2024-11-16T01:10:04Z","timestamp":1731719404963,"version":"3.28.0"},"reference-count":15,"publisher":"Texas Heart Institute Journal","issue":"2","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:sec>\n<jats:title>Background:<\/jats:title>\n<jats:p>The appropriateness of aortic valve surgery for patients with moderate aortic valve regurgitation undergoing coronary artery bypass graft (CABG), mitral valve replacement (MVR), or both is uncertain. This study aimed to investigate the outcomes of moderate aortic valve regurgitation following these procedures.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Methods:<\/jats:title>\n<jats:p>This retrospective cohort study included 113 eligible participants with moderate aortic valve regurgitation who underwent CABG, MVR, or both procedures between January 2014 and January 2015 at Tehran Heart Center. Echocardiographic index data were extracted from the Tehran Heart Center data center after a 2-year follow-up to examine changes in the patients\u2019 conditions.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Results:<\/jats:title>\n<jats:p>A total of 113 patients (mean [SD] age, 64.7 [9.9] years; 78 [69.0%] female patients) were included in the study and followed up for a mean (SD) of 24 (6) months. Among those patients, 38 (33.6%) experienced improvement, with their aortic valve regurgitation downgraded to mild, while the remaining 75 (66.4%) patients maintained a moderate aortic valve regurgitation level. Notably, combined CABG and MVR procedures were associated with statistically significant improvement, with all cases downgraded to mild aortic valve regurgitation. Baseline characteristics, including diabetes, hypertension, dyslipidemia, smoking, family history of aortic valve regurgitation, and a history of drug use, did not differ statistically significantly between patients with improved aortic valve regurgitation and patients with no changes. Echocardiographic indices related to the aorta, such as aortic valve pressure gradient, showed improvement (<jats:italic>P<\/jats:italic> &lt; .001), and ejection fractions before and after surgery remained comparable. Changes in aortic valve regurgitation severity were found to differ statistically significantly between the various procedures (<jats:italic>P<\/jats:italic> = .001).<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Conclusion:<\/jats:title>\n<jats:p>These findings suggest that it is not likely that moderate aortic valve regurgitation will progress after CABG or MVR. Hence, no support was found for concurrent aortic valve replacement during these procedures.<\/jats:p>\n<\/jats:sec>","DOI":"10.14503\/thij-23-8273","type":"journal-article","created":{"date-parts":[[2024,11,15]],"date-time":"2024-11-15T00:30:11Z","timestamp":1731630611000},"source":"Crossref","is-referenced-by-count":0,"title":["Follow-Up Report of Patients With Moderate Aortic Valve Regurgitation After Cardiac Surgery"],"prefix":"10.14503","volume":"51","author":[{"given":"Arezou","family":"Zoroufian","sequence":"first","affiliation":[{"name":"Echocardiography Department, Tehran Heart Center, Tehran University of Medical Science, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arya","family":"Afrooghe","sequence":"additional","affiliation":[{"name":"School of Medicine, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manouchehr","family":"Ziafat","sequence":"additional","affiliation":[{"name":"Echocardiography Department, Tehran Heart Center, Tehran University of Medical Science, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arash","family":"Jalali","sequence":"additional","affiliation":[{"name":"Cardiac Primary Prevention Research Center, Cardiovascular Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran"},{"name":"Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammadreza","family":"Babaei","sequence":"additional","affiliation":[{"name":"School of Medicine, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pooria","family":"Ahmadi","sequence":"additional","affiliation":[{"name":"Echocardiography Department, Dr Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hakimeh","family":"Sadeghian","sequence":"additional","affiliation":[{"name":"Echocardiography Department, Dr Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5628","reference":[{"key":"b1","series-title":"StatPearls","article-title":"Aortic Regurgitation","author":"Dewaswala N","year":"2023","unstructured":"Dewaswala N, Chait R. Aortic Regurgitation. In: StatPearls. StatPearls Publishing; 2023. Updated August 8, 2023. Accessed November 4, 2024. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK555944\/"},{"issue":"6","key":"b2","series-title":"Am J Cardiol","first-page":"897","article-title":"Prevalence and clinical determinants of mitral, tricuspid, and aortic regurgitation (the Framingham Heart Study)","volume":"83","author":"Singh JP","year":"1999","unstructured":"Singh JP, Evans JC, Levy D, et al. Prevalence and clinical determinants of mitral, tricuspid, and aortic regurgitation (the Framingham Heart Study). Am J Cardiol. 1999;83(6):897-902. doi:10.1016\/s0002-9149(98)01064-9"},{"issue":"2","key":"b3","series-title":"Struct Heart","first-page":"87","article-title":"Aortic valve regurgitation: pathophysiology and implications for surgical intervention in the era of TAVR","volume":"4","author":"Ravalli F","year":"2020","unstructured":"Ravalli F, Kossar AP, Takayama H, Grau JB, Ferrari G. Aortic valve regurgitation: pathophysiology and implications for surgical intervention in the era of TAVR. Struct Heart. 2020;4(2):87-98. doi:10.1080\/24748706.2020.1719446"},{"issue":"2","key":"b4","series-title":"J Heart Valve Dis","first-page":"192","article-title":"Mid-term echocardiographic progression of patients with moderate aortic regurgitation: implications for aortic valve surgery","volume":"22","author":"Weisenberg D","year":"2013","unstructured":"Weisenberg D, Omelchenko A, Shapira Y, et al. Mid-term echocardiographic progression of patients with moderate aortic regurgitation: implications for aortic valve surgery. J Heart Valve Dis. 2013;22(2):192-194."},{"issue":"4","key":"b5","series-title":"Eur J Cardiothorac Surg","first-page":"535","article-title":"Management of mild to moderate aortic valve disease during coronary artery bypass grafting","volume":"24","author":"Ahmed AAM","year":"2003","unstructured":"Ahmed AAM, Graham ANJ, Lovell D, O'Kane HO. 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