{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,12,13]],"date-time":"2024-12-13T05:33:34Z","timestamp":1734068014202,"version":"3.30.2"},"reference-count":18,"publisher":"Texas Heart Institute Journal","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:sec>\n<jats:title>Background:<\/jats:title>\n<jats:p>Atrial fibrillation (AF) is a recognized risk factor for mortality after transcatheter aortic valve replacement for severe aortic stenosis, but the impact of different types of AF on clinical outcomes remains unclear.<\/jats:p>\n<\/jats:sec>\n<jats:sec sec-type=\"methods\">\n<jats:title>Methods:<\/jats:title>\n<jats:p>This retrospective study included 982 patients divided into 3 groups: no AF, paroxysmal AF, and nonparoxysmal AF (persistent or permanent). Clinical outcomes were analyzed using inverse probability weighting and multivariate models.<\/jats:p>\n<\/jats:sec>\n<jats:sec sec-type=\"results\">\n<jats:title>Results:<\/jats:title>\n<jats:p>There were 610, 211, and 161 patients in the no-AF, paroxysmal AF, and nonparoxysmal AF groups, respectively. For the entire cohort, the mean (SD) age was 82 (7.7) years, and the periprocedural, 1-year, and 5-year mortality rates were 2.0%, 12%, and 50%, respectively. After inverse probability weighting, the periprocedural mortality rate was higher in the nonparoxysmal AF group than in the no-AF group (odds ratio, 4.71 [95% CI, 1.24-17.9]). During 5 years of follow-up (median [IQR], 22 [0-69] months), all-cause mortality was higher in the nonparoxysmal AF group than in the no-AF group (hazard ratio [HR], 1.56 [95% CI, 1.14-2.14]; <jats:italic>P<\/jats:italic> = .006). The paroxysmal AF group was not associated with worse clinical outcomes than the no-AF group (HR, 1.02 [95% CI, 0.81-1.49]) for all-cause mortality. Stroke rates were comparable among the 3 groups. Multivariate analysis also showed increased all-cause mortality in the nonparoxysmal AF group compared with the no-AF group (adjusted HR, 1.43 [95% CI, 1.06-1.93]; <jats:italic>P<\/jats:italic> = .018), while all-cause mortality was comparable between the paroxysmal AF and no-AF groups (adjusted HR, 1.00 [95% CI, 0.75-1.33]).<\/jats:p>\n<\/jats:sec>\n<jats:sec sec-type=\"conclusions\">\n<jats:title>Conclusion:<\/jats:title>\n<jats:p>In patients undergoing transcatheter aortic valve replacement for severe aortic stenosis, having nonparoxysmal AF was associated with a higher risk of periprocedural and all-cause mortality compared with having no AF. Paroxysmal AF showed no such association.<\/jats:p>\n<\/jats:sec>","DOI":"10.14503\/thij-24-8402","type":"journal-article","created":{"date-parts":[[2024,12,13]],"date-time":"2024-12-13T00:30:56Z","timestamp":1734049856000},"source":"Crossref","is-referenced-by-count":0,"title":["Impact of Atrial Fibrillation Type on Outcomes of Transcatheter Aortic Valve Replacement for Aortic Stenosis: A Single-Center Analysis"],"prefix":"10.14503","volume":"51","author":[{"given":"Yoshiyuki","family":"Yamashita","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Surgery Research, Lankenau Institute for Medical Research, Wynnewood, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serge","family":"Sicouri","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery Research, Lankenau Institute for Medical Research, Wynnewood, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Massimo","family":"Baudo","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery Research, Lankenau Institute for Medical Research, Wynnewood, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Rodriguez","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Lankenau Heart Institute, Main Line Health, Wynnewood, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric M.","family":"Gnall","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology, Lankenau Heart Institute, Main Line Health, Wynnewood, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul M.","family":"Coady","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology, Lankenau Heart Institute, Main Line Health, Wynnewood, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harish","family":"Jarrett","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Disease, Lankenau Heart Institute, Main Line Health, Wynnewood, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra V.","family":"Abramson","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Disease, Lankenau Heart Institute, Main Line Health, Wynnewood, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katie M.","family":"Hawthorne","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Disease, Lankenau Heart Institute, Main Line Health, Wynnewood, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott M.","family":"Goldman","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Lankenau Heart Institute, Main Line Health, Wynnewood, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William A.","family":"Gray","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology, Lankenau Heart Institute, Main Line Health, Wynnewood, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Basel","family":"Ramlawi","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery Research, Lankenau Institute for Medical Research, Wynnewood, Pennsylvania"},{"name":"Department of Cardiothoracic Surgery, Lankenau Heart Institute, Main Line Health, Wynnewood, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5628","reference":[{"key":"b1","series-title":"Int J Cardiol","first-page":"131445","article-title":"Aging and atrial fibrillation: a vicious circle","volume":"395","author":"Gao P","year":"2024","unstructured":"Gao P, Gao X, Xie B, Tse G, Liu T. 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