{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,25]],"date-time":"2025-03-25T01:10:11Z","timestamp":1742865011703,"version":"3.40.2"},"reference-count":15,"publisher":"Texas Heart Institute Journal","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:p>The AVEIR DR (Abbott Medical) was the first dual-chamber leadless pacing system approved by the US Food and Drug Administration. Many patients with sinus node dysfunction have physiologically normal atrioventricular conduction, so an atrial-only pacing system may be appropriate for them. Three patients with symptomatic sinus node dysfunction underwent device implantation with electrophysiologic study, including incremental atrial pacing until loss of 1:1 atrioventricular conduction (atrioventricular Wenckebach cycle length) and His-ventricular interval measurement. If the atrioventricular Wenckebach cycle length was no more than 400 milliseconds and the His-ventricular interval measurement was no more than 55 milliseconds, single-chamber atrial implantation was deemed appropriate. Each patient displayed a different response to atrioventricular conduction testing, demonstrating how electrophysiologic study before device implantation may identify patients for whom atrial-only pacing is not appropriate.<\/jats:p>","DOI":"10.14503\/thij-24-8495","type":"journal-article","created":{"date-parts":[[2025,3,25]],"date-time":"2025-03-25T00:02:40Z","timestamp":1742860960000},"source":"Crossref","is-referenced-by-count":0,"title":["The Role of Electrophysiologic Study in Device Selection for Leadless Atrial Pacing"],"prefix":"10.14503","volume":"52","author":[{"given":"Joshua R.","family":"Hirsch","sequence":"first","affiliation":[{"name":"Section of Cardiology, Baylor College of Medicine, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jordan M.","family":"Gales","sequence":"additional","affiliation":[{"name":"Section of Cardiology, Baylor College of Medicine, Houston, Texas"},{"name":"Department of Cardiology, The Texas Heart Institute at Baylor St Luke's Medical Center, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irakli","family":"Giorgberidze","sequence":"additional","affiliation":[{"name":"Section of Cardiology, Baylor College of Medicine, Houston, Texas"},{"name":"Department of Cardiology, Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamid","family":"Afshar","sequence":"additional","affiliation":[{"name":"Section of Cardiology, Baylor College of Medicine, Houston, Texas"},{"name":"Department of Cardiology, Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5628","reference":[{"issue":"8","key":"b1","series-title":"Circulation","first-page":"e382","article-title":"2018 ACC\/AHA\/HRS Guideline on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction Delay: a report of the American College of Cardiology\/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society","volume":"140","author":"Kusumoto FM","year":"2019","unstructured":"Kusumoto FM, Schoenfeld MH, Barrett C, et al. 2018 ACC\/AHA\/HRS Guideline on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction Delay: a report of the American College of Cardiology\/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society. Circulation. 2019;140(8):e382-e482. doi:10.1161\/CIR.0000000000000628"},{"issue":"3","key":"b2","series-title":"Am J Physiol Heart Circ Physiol","first-page":"H259","article-title":"Sinus node dysfunction: current understanding and future directions","volume":"324","author":"Manoj P","year":"2023","unstructured":"Manoj P, Kim JA, Kim S, et al. Sinus node dysfunction: current understanding and future directions. Am J Physiol Heart Circ Physiol. 2023;324(3):H259-H278. doi:10.1152\/ajpheart.00618.2022"},{"issue":"16","key":"b3","series-title":"J Am Coll Cardiol","first-page":"1540","article-title":"Trends in permanent pacemaker implantation in the United States from 1993 to 2009: increasing complexity of patients and procedures","volume":"60","author":"Greenspon AJ","year":"2012","unstructured":"Greenspon AJ, Patel JD, Lau E, et al. Trends in permanent pacemaker implantation in the United States from 1993 to 2009: increasing complexity of patients and procedures. J Am Coll Cardiol. 2012;60(16):1540-1545. doi:10.1016\/j.jacc.2012.07.017"},{"issue":"6","key":"b4","series-title":"Eur Heart J","first-page":"686","article-title":"DANPACE Investigators. A comparison of single-lead atrial pacing with dual-chamber pacing in sick sinus syndrome","volume":"32","author":"Nielsen JC","year":"2011","unstructured":"Nielsen JC, Thomsen PEB, H\u00f8jberg S, et al; DANPACE Investigators. A comparison of single-lead atrial pacing with dual-chamber pacing in sick sinus syndrome. Eur Heart J. 2011;32(6):686-696. doi:10.1093\/eurheartj\/ehr022"},{"issue":"12","key":"b5","series-title":"Europace","first-page":"1981","article-title":"Single lead atrial vs. dual chamber pacing in sick sinus syndrome: extended register-based follow-up in the DANPACE trial","volume":"19","author":"Brandt NH","year":"2017","unstructured":"Brandt NH, Kirkfeldt RE, Nielsen JC, et al. Single lead atrial vs. dual chamber pacing in sick sinus syndrome: extended register-based follow-up in the DANPACE trial. Europace. 2017;19(12):1981-1987. doi:10.1093\/europace\/euw364"},{"issue":"25","key":"b6","series-title":"N Engl J Med","first-page":"2360","article-title":"Aveir DR i2i Study Investigators. A dual-chamber leadless pacemaker","volume":"388","author":"Knops RE","year":"2023","unstructured":"Knops RE, Reddy VY, Ip JE, et al; Aveir DR i2i Study Investigators. A dual-chamber leadless pacemaker. N Engl J Med. 2023;388(25):2360-2370. doi:10.1056\/NEJMoa2300080"},{"issue":"7","key":"b7","series-title":"Circ Arrhythm Electrophysiol","article-title":"Wireless communication between paired leadless pacemakers for dual-chamber synchrony","volume":"15","author":"Cantillon DJ","year":"2022","unstructured":"Cantillon DJ, Gambhir A, Banker R, et al. Wireless communication between paired leadless pacemakers for dual-chamber synchrony. Circ Arrhythm Electrophysiol. 2022;15(7):e010909. doi:10.1161\/CIRCEP.122.010909"},{"issue":"9","key":"b8","series-title":"Europace","article-title":"Anatomic, histologic, and mechanical features of the right atrium: implications for leadless atrial pacemaker implantation","volume":"25","author":"O\u2019Connor M","year":"2023","unstructured":"O\u2019Connor M, Barbero U, Kramer DB, et al. Anatomic, histologic, and mechanical features of the right atrium: implications for leadless atrial pacemaker implantation. Europace. 2023;25(9):euad235. doi:10.1093\/europace\/euad235"},{"issue":"9","key":"b9","series-title":"J Interv Card Electrophysiol","first-page":"1955","article-title":"The 1st implantation of an atrial only leadless pacemaker in right atrial appendage","volume":"66","author":"Sundaram S","year":"2023","unstructured":"Sundaram S, Alyesh D, Walker L, Zipse MM. The 1st implantation of an atrial only leadless pacemaker in right atrial appendage. J Interv Card Electrophysiol. 2023;66(9):1955-1958. doi:10.1007\/s10840-023-01644-3"},{"issue":"11","key":"b10","series-title":"JACC Clin Electrophysiol","first-page":"1296","article-title":"Complications and health care costs associated with transvenous cardiac pacemakers in a nationwide assessment","volume":"3","author":"Cantillon DJ","year":"2017","unstructured":"Cantillon DJ, Exner DV, Badie N, et al. Complications and health care costs associated with transvenous cardiac pacemakers in a nationwide assessment. JACC Clin Electrophysiol. 2017;3(11):1296-1305. doi:10.1016\/j.jacep.2017.05.007"},{"issue":"7","key":"b11","series-title":"Heart Rhythm","first-page":"1023","article-title":"Comparative study of acute and mid-term complications with leadless and transvenous cardiac pacemakers","volume":"15","author":"Cantillon DJ","year":"2018","unstructured":"Cantillon DJ, Dukkipati SR, Ip JH, et al. Comparative study of acute and mid-term complications with leadless and transvenous cardiac pacemakers. Heart Rhythm. 2018;15(7):1023-1030. doi:10.1016\/j.hrthm.2018.04.022"},{"issue":"10","key":"b12","series-title":"JAMA Cardiol","first-page":"1187","article-title":"Contemporaneous comparison of outcomes among patients implanted with a leadless vs transvenous single-chamber ventricular pacemaker","volume":"6","author":"Piccini JP","year":"2021","unstructured":"Piccini JP, El-Chami M, Wherry K, et al. Contemporaneous comparison of outcomes among patients implanted with a leadless vs transvenous single-chamber ventricular pacemaker. 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