{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T19:34:16Z","timestamp":1754163256503,"version":"3.41.2"},"reference-count":14,"publisher":"Texas Heart Institute Journal","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:p>This case study explores the journey of an 80-year-old male patient with a history of hypertension, diabetes, coronary artery disease after coronary artery bypass grafting, atrial fibrillation, and heart failure. Nine months before he presented to the emergency department, he had undergone mitral valve clipping for severe mitral valve regurgitation. Despite initial improvement, the patient experienced return of symptoms, including dyspnea at rest and lower limb edema. The results of this case\u2014discovery of the need for mitral valve replacement\u2014provides insights into the management of complications from mitral valve clipping and emphasizes that management requires a nuanced, meticulous approach.<\/jats:p>","DOI":"10.14503\/thij-25-8559","type":"journal-article","created":{"date-parts":[[2025,7,31]],"date-time":"2025-07-31T00:31:12Z","timestamp":1753921872000},"source":"Crossref","is-referenced-by-count":0,"title":["Navigating the Complexities of Mitral Valve Clipping: Early Severe Mitral Valve Stenosis After Mitral Valve Clipping"],"prefix":"10.14503","volume":"52","author":[{"given":"Wassim","family":"Abouzeid","sequence":"first","affiliation":[{"name":"Departments of Cardiology and Internal Medicine, Saint Michael's Medical Center, Newark, New Jersey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmad","family":"Haddad","sequence":"additional","affiliation":[{"name":"Departments of Cardiology and Internal Medicine, Saint Michael's Medical Center, Newark, New Jersey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chrystina","family":"Kiwan","sequence":"additional","affiliation":[{"name":"Departments of Cardiology and Internal Medicine, Saint Michael's Medical Center, Newark, New Jersey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahsan","family":"Khan","sequence":"additional","affiliation":[{"name":"Departments of Cardiology and Internal Medicine, Saint Michael's Medical Center, Newark, New Jersey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Addi","family":"Suleiman","sequence":"additional","affiliation":[{"name":"Departments of Cardiology and Internal Medicine, Saint Michael's Medical Center, Newark, New Jersey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5628","reference":[{"issue":"4","key":"b1","series-title":"J Am Coll Cardiol","first-page":"e25","article-title":"2020 ACC\/AHA guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines","volume":"77","author":"Writing Committee Members","year":"2021","unstructured":"Writing Committee Members; Otto CM, Nishimura RA, Bonow RO, et al. 2020 ACC\/AHA guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines. J Am Coll Cardiol. 2021;77(4):e25-e197. doi:10.1016\/j.jacc.2020.11.018"},{"issue":"4","key":"b2","series-title":"J Am Heart Assoc","article-title":"Percutaneous MitraClip device or surgical mitral valve repair in patients with primary mitral regurgitation who are candidates for surgery: design and rationale of the REPAIR MR trial","volume":"12","author":"McCarthy PM","year":"2023","unstructured":"McCarthy PM, Whisenant B, Asgar AW, et al. Percutaneous MitraClip device or surgical mitral valve repair in patients with primary mitral regurgitation who are candidates for surgery: design and rationale of the REPAIR MR trial. J Am Heart Assoc. 2023;12(4):e027504. doi:10.1161\/JAHA.122.027504"},{"issue":"11","key":"b3","series-title":"J Am Coll Cardiol","first-page":"2134","article-title":"Percutaneous mitral valve repair using the edge-to-edge technique: six-month results of the EVEREST phase I clinical trial","volume":"46","author":"Feldman T","year":"2005","unstructured":"Feldman T, Wasserman HS, Herrmann HC, et al. Percutaneous mitral valve repair using the edge-to-edge technique: six-month results of the EVEREST phase I clinical trial. J Am Coll Cardiol. 2005;46(11):2134-2140. doi:10.1016\/j.jacc.2005.07.065"},{"issue":"2","key":"b4","series-title":"ESC Heart Fail","first-page":"1122","article-title":"EXPAND investigators. Safety and efficacy of MitraClip in acutely ill (NYHA class IV) patients with mitral regurgitation: results from the global EXPAND study","volume":"10","author":"Shuvy M","year":"2023","unstructured":"Shuvy M, von Bardeleben RS, Grasso C, et al; EXPAND investigators. Safety and efficacy of MitraClip in acutely ill (NYHA class IV) patients with mitral regurgitation: results from the global EXPAND study. ESC Heart Fail. 2023;10(2):1122-1132. doi:10.1002\/ehf2.14273"},{"issue":"8","key":"b5","series-title":"J Am Coll Cardiol","first-page":"1029","article-title":"COAPT investigators. 3-year outcomes of transcatheter mitral valve repair in patients with heart failure","volume":"77","author":"Mack MJ","year":"2021","unstructured":"Mack MJ, Lindenfeld J, Abraham WT, et al; COAPT investigators. 3-year outcomes of transcatheter mitral valve repair in patients with heart failure. J Am Coll Cardiol. 2021;77(8):1029-1040. doi:10.1016\/j.jacc.2020.12.047"},{"key":"b6","series-title":"J Am Coll Cardiol","first-page":"E1959","article-title":"The EVEREST II REALISM Continued Access study: effectiveness of transcatheter reduction of significant mitral regurgitation in surgical candidates","volume":"61","author":"Kar S","year":"2013","unstructured":"Kar S, Lim D, Smalling R, et al. The EVEREST II REALISM Continued Access study: effectiveness of transcatheter reduction of significant mitral regurgitation in surgical candidates. J Am Coll Cardiol. 2013;61(10_suppl):E1959."},{"issue":"20","key":"b7","series-title":"JACC Cardiovasc Interv","first-page":"2402","article-title":"Transcatheter edge-to-edge mitral valve repair with the MitraClip G4 System","volume":"13","author":"Chakravarty T","year":"2020","unstructured":"Chakravarty T, Makar M, Patel D, et al. Transcatheter edge-to-edge mitral valve repair with the MitraClip G4 System. JACC Cardiovasc Interv. 2020;13(20):2402-2414. doi:10.1016\/j.jcin.2020.06.053"},{"key":"b8","article-title":"Contemporary clinical outcomes with MitraClip\u2122 G4 System: core\u2010lab echo results from the first 100 patients in the EXPAND G4 study","author":"Chehab B","year":"2020","unstructured":"Chehab B, Price M, Morse AM, et al. Contemporary clinical outcomes with MitraClip\u2122 G4 System: core\u2010lab echo results from the first 100 patients in the EXPAND G4 study. Poster presented at: PCR Valves e\u2010Course; 2020; virtual meeting."},{"issue":"15","key":"b9","series-title":"N Engl J Med","first-page":"1395","article-title":"EVEREST II investigators. Percutaneous repair or surgery for mitral regurgitation","volume":"364","author":"Feldman T","year":"2011","unstructured":"Feldman T, Foster E, Glower DD, et al; EVEREST II investigators. Percutaneous repair or surgery for mitral regurgitation. N Engl J Med. 2011;364(15):1395-1406. doi:10.1056\/NEJMoa1009355"},{"issue":"2","key":"b10","series-title":"Catheter Cardiovasc Interv","first-page":"297","article-title":"Development of mitral stenosis after single MitraClip insertion for severe mitral regurgitation","volume":"83","author":"Cockburn J","year":"2014","unstructured":"Cockburn J, Fragkou P, Hildick-Smith D. Development of mitral stenosis after single MitraClip insertion for severe mitral regurgitation. Catheter Cardiovasc Interv. 2014;83(2):297-302. doi:10.1002\/ccd.25011"},{"issue":"22","key":"b11","series-title":"N Eng J Med","first-page":"2037","article-title":"COAPT investigators. Five-year follow-up after transcatheter repair of secondary mitral regurgitation","volume":"388","author":"Stone GW","year":"2023","unstructured":"Stone GW, Abraham WT, Lindenfeld J, et al; COAPT investigators. Five-year follow-up after transcatheter repair of secondary mitral regurgitation. N Eng J Med. 2023;388(22):2037-2048. doi:10.1056\/NEJMoa2300213"},{"issue":"8","key":"b12","series-title":"JACC Cardiovasc Interv","first-page":"879","article-title":"Effect of mitral valve gradient after MitraClip on outcomes in secondary mitral regurgitation: results from the COAPT trial","volume":"14","author":"Halaby R","year":"2021","unstructured":"Halaby R, Herrmann HC, Gertz ZM, et al. Effect of mitral valve gradient after MitraClip on outcomes in secondary mitral regurgitation: results from the COAPT trial. JACC Cardiovasc Interv. 2021;14(8):879-889. doi:10.1016\/j.jcin.2021.01.049"},{"issue":"18","key":"b13","series-title":"JACC Cardiovasc Interv","first-page":"2010","article-title":"CUTTING-EDGE Investigators. Mitral valve surgery after transcatheter edge-to-edge repair: mid-term outcomes from the CUTTING-EDGE international registry","volume":"14","author":"Kaneko T","year":"2021","unstructured":"Kaneko T, Hirji S, Zaid S, et al; CUTTING-EDGE Investigators. Mitral valve surgery after transcatheter edge-to-edge repair: mid-term outcomes from the CUTTING-EDGE international registry. JACC Cardiovasc Interv. 2021;14(18):2010-2021. doi:10.1016\/j.jcin.2021.07.029"},{"issue":"1","key":"b14","series-title":"N Engl J Med","first-page":"23","article-title":"CTSN. Mitral-valve repair versus replacement for severe ischemic mitral regurgitation","volume":"370","author":"Acker MA","year":"2014","unstructured":"Acker MA, Parides MK, Perrault LP, et al; CTSN. Mitral-valve repair versus replacement for severe ischemic mitral regurgitation. N Engl J Med. 2014;370(1):23-32. doi:10.1056\/NEJMoa1312808"}],"container-title":["Texas Heart Institute Journal"],"original-title":[],"link":[{"URL":"https:\/\/thij.kglmeridian.com\/view\/journals\/thij\/52\/2\/article-e258559.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thij.kglmeridian.com\/downloadpdf\/journals\/thij\/52\/2\/article-e258559.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thij.kglmeridian.com\/downloadpdf\/journals\/thij\/52\/2\/article-e258559.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,31]],"date-time":"2025-07-31T00:31:13Z","timestamp":1753921873000},"score":1,"resource":{"primary":{"URL":"https:\/\/thij.kglmeridian.com\/view\/journals\/thij\/52\/2\/article-e258559.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":14,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.14503\/thij-25-8559","relation":{},"ISSN":["1526-6702","0730-2347"],"issn-type":[{"type":"electronic","value":"1526-6702"},{"type":"print","value":"0730-2347"}],"subject":[],"published":{"date-parts":[[2025]]}}}