{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T03:05:37Z","timestamp":1787022337436,"version":"build-2736575974"},"reference-count":25,"publisher":"Pacini Editore","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Otorhinolaryngol Ital"],"DOI":"10.14639\/0392-100x-n0870","type":"journal-article","created":{"date-parts":[[2021,9,17]],"date-time":"2021-09-17T13:05:54Z","timestamp":1631883954000},"page":"317-326","source":"Crossref","is-referenced-by-count":6,"title":["Organ preservation and oncological outcomes in early laryngeal cancer: a propensity score-based study","Preservazione d\u2019organo ed esiti oncologici nel carcinoma laringeo in stadio iniziale: uno studio basato sul punteggio di propensione"],"prefix":"10.14639","volume":"41","author":[{"given":"Genival Barbosa","family":"de Carvalho","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugo Fontan","family":"Kohler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia Bette Homem","family":"de Mello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renan Bezerra","family":"Lira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio C\u00e1ssio de Assis","family":"Pellizzon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Guilherme","family":"Vartanian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luiz Paulo","family":"Kowalski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"20340","published-online":{"date-parts":[[2021,8]]},"reference":[{"key":"10.14639\/0392-100X-N0870_ref1","doi-asserted-by":"crossref","unstructured":"Kowalski LP, Batista MB, Santos CR, et al. Prognostic factors in glottic carcinoma clinical stage I and II treated by surgery or radiotherapy. Am J Otolaryngol 1993;14:122-127.","DOI":"10.1016\/0196-0709(93)90051-8"},{"key":"10.14639\/0392-100X-N0870_ref2","doi-asserted-by":"crossref","unstructured":"Ansarin M, Zabrodsky M, Bianchi L, et al. Endoscopic CO2 laser surgery for early glottic cancer in patients who are candidates for radiotherapy: results of a prospective nonrandomized study. Head Neck 2006;28:121-125. https:\/\/doi.org\/10.1002\/hed.20301","DOI":"10.1002\/hed.20301"},{"key":"10.14639\/0392-100X-N0870_ref3","doi-asserted-by":"crossref","unstructured":"Jones DA, Mendenhall CM, Kirwan J, et al. Radiation therapy for management of t1-t2 glottic cancer at a private practice. Am J Clin Oncol 2010;33:587-590. https:\/\/doi.org\/10.1097\/COC.0b013e3181beaab0","DOI":"10.1097\/COC.0b013e3181beaab0"},{"key":"10.14639\/0392-100X-N0870_ref4","doi-asserted-by":"crossref","unstructured":"Thomas L, Drinnan M, Natesh B, et al. Open conservation partial laryngectomy for laryngeal cancer: a systematic review of English language literature. Cancer Treat Rev 2012;38:203-211. https:\/\/doi.org\/10.1016\/j.ctrv.2011.05.010","DOI":"10.1016\/j.ctrv.2011.05.010"},{"key":"10.14639\/0392-100X-N0870_ref5","doi-asserted-by":"crossref","unstructured":"O\u2019Hara J, Markey A, Homer JJ. Transoral laser surgery versus radiotherapy for tumour stage 1a or 1b glottic squamous cell carcinoma: systematic review of local control outcomes. J Laryngol Otol 2013;127:732-738. https:\/\/doi.org\/10.1017\/S0022215113001400","DOI":"10.1017\/S0022215113001400"},{"key":"10.14639\/0392-100X-N0870_ref6","doi-asserted-by":"crossref","unstructured":"Warner L, Chudasama J, Kelly CG, et al. Radiotherapy versus open surgery versus endolaryngeal surgery (with or without laser) for early laryngeal squamous cell cancer. Cochrane Database Syst Rev 2014;12:CD002027. https:\/\/doi.org\/ 10.1002\/14651858.CD002027","DOI":"10.1002\/14651858.CD002027.pub2"},{"key":"10.14639\/0392-100X-N0870_ref7","doi-asserted-by":"crossref","unstructured":"Yoo J, Lacchetti C, Hammond JA, et al. Role of endolaryngeal surgery (with or without laser) versus radiotherapy in the management of early (T1) glottic cancer: a systematic review. Head Neck 2014;36:1807-1819. https:\/\/doi.org\/10.1002\/hed.23504","DOI":"10.1002\/hed.23504"},{"key":"10.14639\/0392-100X-N0870_ref8","doi-asserted-by":"crossref","unstructured":"Hendriksma M, Heijnen BJ, Sj\u00f6gren EV. Oncologic and functional outcomes of patients treated with transoral CO2 laser microsurgery or radiotherapy for T2 glottic carcinoma: a systematic review of the literature. Curr Opin Otolaryngol Head Neck Surg 2018;26:84-93. https:\/\/doi.org\/10.1097\/MOO.0000000000000438.","DOI":"10.1097\/MOO.0000000000000438"},{"key":"10.14639\/0392-100X-N0870_ref9","doi-asserted-by":"crossref","unstructured":"Guimar\u00e3es AV, Dedivitis RA, Matos LL, et al. Comparison between transoral laser surgery and radiotherapy in the treatment of early glottic cancer: a systematic review and meta-analysis. Sci Rep 2018;8:11900. https:\/\/doi.org\/10.1038\/s41598-018-30218-x","DOI":"10.1038\/s41598-018-30218-x"},{"key":"10.14639\/0392-100X-N0870_ref10","unstructured":"Amin MB, Edge SB, Greene FL, et al. AJCC Cancer Staging Manual. Eighth edition. New York: Springer; 2017. Larynx; pp. 46-64."},{"key":"10.14639\/0392-100X-N0870_ref11","doi-asserted-by":"crossref","unstructured":"Loux TM. Randomization, matching, and propensity scores in the design and analysis of experimental studies with measured baseline covariates. Stat Med 2015;34:558-570. https:\/\/doi.org\/10.1002\/sim.6361","DOI":"10.1002\/sim.6361"},{"key":"10.14639\/0392-100X-N0870_ref12","doi-asserted-by":"crossref","unstructured":"Abdurehim Y, Hua Z, Yasin Y, et al. Transoral laser surgery versus radiotherapy: systematic review and meta-analysis for treatment options of T1a glottic cancer. Head Neck 2012;34:23-33. https:\/\/doi.org\/10.1002\/hed.21686","DOI":"10.1002\/hed.21686"},{"key":"10.14639\/0392-100X-N0870_ref13","doi-asserted-by":"crossref","unstructured":"Succo G, Crosetti E, Bertolin A, et al. Benefits and drawbacks of open partial horizontal laryngectomies. Part A: early-to intermediate-stage glottic carcinoma. Head Neck 2016;38:333-340. https:\/\/doi.org\/10.1002\/hed.23997","DOI":"10.1002\/hed.23997"},{"key":"10.14639\/0392-100X-N0870_ref14","doi-asserted-by":"crossref","unstructured":"Ansarin M, Cattaneo A, De Benedetto L, et al. Retrospective analysis of factors influencing oncologic outcome in 590 patients with early-intermediate glottic cancer treated by transoral laser microsurgery. Head Neck 2017;39:71-81. https:\/\/doi.org\/10.1002\/hed.24534","DOI":"10.1002\/hed.24534"},{"key":"10.14639\/0392-100X-N0870_ref15","doi-asserted-by":"crossref","unstructured":"Vaculik MF, MacKay CA, Taylor SM, et al. Systematic review and meta-analysis of T1 glottic cancer outcomes comparing CO(2) transoral laser microsurgery and radiotherapy. J Otolaryngol Head Neck Surg 2019;48:44. https:\/\/doi.org\/10.1186\/s40463-019-0367-2","DOI":"10.1186\/s40463-019-0367-2"},{"key":"10.14639\/0392-100X-N0870_ref16","doi-asserted-by":"crossref","unstructured":"Rosier JF, Gr\u00e9goire V, Counoy H, et al. Comparison of external radiotherapy, laser microsurgery and partial laryngectomy for the treatment of T1N0M0 glottic carcinomas: a retrospective evaluation. Radiother Oncol 1998;48:175-183. https:\/\/doi.org\/10.1016\/s0167-8140(98)00058-9","DOI":"10.1016\/S0167-8140(98)00058-9"},{"key":"10.14639\/0392-100X-N0870_ref17","doi-asserted-by":"crossref","unstructured":"Aaltonen LM, Rautiainen N, Sellman J, et al. Voice quality after treatment of early vocal cord cancer: a randomized trial comparing laser surgery with radiation therapy. Int J Radiat Oncol Biol Phys 2014;90:255-260. https:\/\/doi.org\/10.1016\/j.ijrobp.2014.06.032","DOI":"10.1016\/j.ijrobp.2014.06.032"},{"key":"10.14639\/0392-100X-N0870_ref18","doi-asserted-by":"crossref","unstructured":"Locatello LG, Cannavicci A, Gallo O. Prognostic impact of initial treatment in surgically salvaged recurrences of early glottic cancer. Laryngoscope 2019;129:2328-2333. https:\/\/doi.org\/10.1002\/lary.27702","DOI":"10.1002\/lary.27702"},{"key":"10.14639\/0392-100X-N0870_ref19","doi-asserted-by":"crossref","unstructured":"Bertolin A, Lionello M, Ghizzo M, et al. Salvage open partial horizontal laryngectomy after failed radiotherapy: a multicentric study. Laryngoscope 2020;130:431-436. https:\/\/doi.org\/10.1002\/lary.27959","DOI":"10.1002\/lary.27959"},{"key":"10.14639\/0392-100X-N0870_ref20","doi-asserted-by":"crossref","unstructured":"Pontes P, Brasil Ode O, Amorim Filho Fde S, et al. Radiotherapy for early glottic cancer and salvage surgery after recurrence. Braz J Otorhinolaryngol 2011;77:299-302. https:\/\/doi.org\/10.1590\/s1808-86942011000300005","DOI":"10.1590\/S1808-86942011000300005"},{"key":"10.14639\/0392-100X-N0870_ref21","doi-asserted-by":"crossref","unstructured":"Agra IM, Ferlito A, Takes RP, et al. Diagnosis and treatment of recurrent laryngeal cancer following initial nonsurgical therapy. Head Neck 2012;34:727-735. https:\/\/doi.org\/10.1002\/hed.21739","DOI":"10.1002\/hed.21739"},{"key":"10.14639\/0392-100X-N0870_ref22","doi-asserted-by":"crossref","unstructured":"Mendenhall WM, Parsons JT, Stringer SP, et al. Management of Tis, T1, and T2 squamous cell carcinoma of the glottic larynx. Am J Otolaryngol 1994;15:250-257. https:\/\/doi.org\/10.1016\/0196-0709(94)90091-4","DOI":"10.1016\/0196-0709(94)90091-4"},{"key":"10.14639\/0392-100X-N0870_ref23","doi-asserted-by":"crossref","unstructured":"Franchin G, Minatel E, Gobitti C, et al. Radiation treatment of glottic squamous cell carcinoma, stage I and II: analysis of factors affecting prognosis. Int J Radiat Oncol Biol Phys 1998;40:541-548. https:\/\/doi.org\/10.1016\/s0360-3016(97)00768-2","DOI":"10.1016\/S0360-3016(97)00768-2"},{"key":"10.14639\/0392-100X-N0870_ref24","unstructured":"Enarson DA, Kennedy SM, Miller DL. Choosing a research study design and selecting a population to study. Int J Tuberc Lung Dis 2004;8:1151-1156."},{"key":"10.14639\/0392-100X-N0870_ref25","doi-asserted-by":"crossref","unstructured":"Anglemyer A, Horvath HT, Bero L. Healthcare outcomes assessed with observational study designs compared with those assessed in randomized trials. Cochrane Database Syst Rev 2014;9:MR000034. https:\/\/doi.org\/10.1002\/14651858.MR000034","DOI":"10.1002\/14651858.MR000034.pub2"}],"container-title":["Acta Otorhinolaryngologica Italica"],"original-title":[],"link":[{"URL":"https:\/\/www.actaitalica.it\/article\/view\/870","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,23]],"date-time":"2024-10-23T03:17:25Z","timestamp":1729653445000},"score":1,"resource":{"primary":{"URL":"https:\/\/old.actaitalica.it\/article\/view\/870"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8]]},"references-count":25,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2021,8]]}},"URL":"https:\/\/doi.org\/10.14639\/0392-100x-n0870","relation":{},"ISSN":["1827-675X"],"issn-type":[{"value":"1827-675X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,8]]},"article-number":"4"}}