{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T10:46:54Z","timestamp":1788778014200,"version":"build-2803163510"},"reference-count":21,"publisher":"Charles University in Prague, Karolinum Press","issue":"1","license":[{"start":{"date-parts":[[2014,11,12]],"date-time":"2014-11-12T00:00:00Z","timestamp":1415750400000},"content-version":"vor","delay-in-days":315,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2014,11,12]],"date-time":"2014-11-12T00:00:00Z","timestamp":1415750400000},"content-version":"tdm","delay-in-days":315,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Med. (Hradec Kralove, Czech Repub.)"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>\n                    Introduction: A previous study has employed shear-wave ultrasound elastographic imaging to assess corneal rigidity in an ex-vivo porcine eye model. This study employs the same modality\n                    <jats:italic>in vivo<\/jats:italic>\n                    in a rabbit eye model in order to assess lens, ciliary body and total ocular rigidity changes following the instillation of atropine and pilocarpine. Methods: Ten non-pigmented female rabbits were examined. Measurements of the lens, ciliary body and total ocular rigidity as well as lens thickness and anterior chamber depth were taken with the Aixplorer system (SuperSonic Imagine, Aix-en-Provence, France) with the SuperLinear\u2122 SL 15-4 transducer in both eyes at baseline as well as after pilocarpine and atropine instillation. The IOP was also measured with the TonoPen tonometer. Results: Changes in rigidity in the examined areas following atropine instillation were statistically not significant. Ciliary body rigidity was significantly increased whereas lens and total ocular rigidity were significantly reduced following pilocarpine instillation. The decrease in lens rigidity following pilocarpine was significantly associated with the respective increase in ciliary body rigidity. Conclusions: Shear-wave ultrasound elastography can detect in vivo rigidity changes in the anterior segment of the rabbit eye model and may potentially be applied in human eyes, providing useful clinical information on conditions in which rigidity changes play an important role, such as glaucoma, pseudoexfoliation syndrome or presbyopia.\n                  <\/jats:p>","DOI":"10.14712\/18059694.2014.2","type":"journal-article","created":{"date-parts":[[2014,11,15]],"date-time":"2014-11-15T17:19:20Z","timestamp":1416071960000},"page":"9-14","source":"Crossref","is-referenced-by-count":15,"title":["EVALUATION OF IRIDOCILIARY AND LENTICULAR ELASTICITY USING SHEAR-WAVE ELASTOGRAPHY IN RABBIT EYES"],"prefix":"10.14712","volume":"57","author":[{"given":"Efstathios T.","family":"Detorakis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleni E.","family":"Drakonaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harilaos","family":"Ginis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikolaos","family":"Karyotakis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ioannis G.","family":"Pallikaris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5727","published-online":{"date-parts":[[2014,11,12]]},"reference":[{"key":"18059694.2014.2_1","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1016\/S0301-5629(01)00433-1","volume":"27","author":"Konofagou","year":"2001","journal-title":"Ultrasound in Med. & Biol."},{"key":"18059694.2014.2_2","doi-asserted-by":"crossref","first-page":"1380","DOI":"10.1016\/j.jbiomech.2010.12.031","volume":"44","author":"Riek","year":"2011","journal-title":"J Biomech."},{"key":"18059694.2014.2_3","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1097\/RUQ.0b013e31822a2138","volume":"27","author":"Garra","year":"2011","journal-title":"Ultrasound Q."},{"key":"18059694.2014.2_4","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.1098\/rsif.2011.0054","volume":"8","author":"Wells","year":"2011","journal-title":"J R Soc Interface."},{"key":"18059694.2014.2_5","doi-asserted-by":"crossref","first-page":"135","DOI":"10.3928\/15428877-20091230-24","volume":"41","author":"Detorakis","year":"2010","journal-title":"Ophthalmic Surgery, Lasers, Imaging."},{"key":"18059694.2014.2_6","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1088\/0031-9155\/57\/1\/21","volume":"57","author":"Hoyt","year":"2012","journal-title":"Phys Med Biol."},{"key":"18059694.2014.2_7","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.1109\/TMI.2009.2021471","volume":"28","author":"Tanter","year":"2009","journal-title":"IEEE Trans Med Imaging."},{"key":"18059694.2014.2_8","first-page":"488","volume":"52","author":"Holve","year":"2013","journal-title":"J Am Assoc Lab Anim Sci."},{"key":"18059694.2014.2_9","first-page":"1117","volume":"2009","author":"Namani","year":"2009","journal-title":"Conf Proc IEEE Eng Med Biol Soc."},{"key":"18059694.2014.2_10","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.ultrasmedbio.2010.11.013","volume":"37","author":"Kapoor","year":"2011","journal-title":"Ultrasound Med Biol."},{"key":"18059694.2014.2_11","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1177\/016173461003200401","volume":"32","author":"Zhai","year":"2010","journal-title":"Ultrason Imaging."},{"key":"18059694.2014.2_12","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1097\/00006324-200004000-00013","volume":"77","author":"Pardue","year":"2000","journal-title":"Optom Vis Sci."},{"key":"18059694.2014.2_13","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1034\/j.1600-0420.1999.770414.x","volume":"77","author":"Celebi","year":"1999","journal-title":"Acta Ophthalmol Scand."},{"key":"18059694.2014.2_14","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1038\/eye.2013.127","volume":"27","author":"Chen","year":"2013","journal-title":"Eye (Lond)."},{"key":"18059694.2014.2_15","doi-asserted-by":"crossref","first-page":"2091","DOI":"10.1016\/S0161-6420(98)91132-0","volume":"105","author":"Marchini","year":"1998","journal-title":"Ophthalmology."},{"key":"18059694.2014.2_16","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1111\/j.1748-1716.1980.tb06553.x","volume":"108","author":"Bill","year":"1980","journal-title":"Acta Physiol Scand."},{"key":"18059694.2014.2_17","first-page":"85","volume":"39","author":"Agrawal","year":"1991","journal-title":"Indian J Ophthalmol."},{"key":"18059694.2014.2_18","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1258\/ar.2011.110276","volume":"52","author":"Tozaki","year":"2011","journal-title":"Acta Radiol."},{"key":"18059694.2014.2_19","first-page":"108","volume":"61","author":"Friedenwald","year":"1957","journal-title":"Trans Am Acad Ophthalmol Otolaryngol."},{"key":"18059694.2014.2_20","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1111\/j.1463-5224.2006.00495.x","volume":"9","author":"Werner","year":"2006","journal-title":"Vet Ophthalmol."},{"key":"18059694.2014.2_21","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1213\/ANE.0b013e318253622e","volume":"115","author":"Palte","year":"2012","journal-title":"Anesth Analg."}],"container-title":["Acta Medica (Hradec Kralove, Czech Republic)"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/actamedica.lfhk.cuni.cz\/media\/pdf\/am_2014057010009.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/actamedica.lfhk.cuni.cz\/media\/pdf\/am_2014057010009.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T09:31:56Z","timestamp":1779960716000},"score":1,"resource":{"primary":{"URL":"https:\/\/actamedica.lfhk.cuni.cz\/57\/1\/0009\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":21,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2014]]}},"alternative-id":["am_2014057010009"],"URL":"https:\/\/doi.org\/10.14712\/18059694.2014.2","relation":{},"ISSN":["1211-4286","1805-9694"],"issn-type":[{"value":"1211-4286","type":"print"},{"value":"1805-9694","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}