{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T04:25:25Z","timestamp":1780460725928,"version":"3.54.1"},"reference-count":11,"publisher":"Charles University in Prague, Karolinum Press","issue":"3","license":[{"start":{"date-parts":[[2015,10,20]],"date-time":"2015-10-20T00:00:00Z","timestamp":1445299200000},"content-version":"vor","delay-in-days":1388,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2015,10,20]],"date-time":"2015-10-20T00:00:00Z","timestamp":1445299200000},"content-version":"tdm","delay-in-days":1388,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Med. (Hradec Kralove, Czech Repub.)"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>Introduction: Obstruction of the appendiceal lumen is the primary cause of appendicitis. The most common causes of luminal obstruction are fecaliths and lymphoid follicle hyperplasia. Additionally, bacterial infections or enteric and systemic viral diseases can cause a reaction of the lymphoid follicle. Case presentation: An 11-year-old boy with active phase of chickenpox presented on our Pediatric surgery emergency department under the impression of acute appendicitis. An appendectomy was performed on the same day. An in\ufb02amed and edematous retrocecal appendix was removed during surgery. Histological investigation of the appendix revealed transmural acute inflammation, with diffuse proliferation of inflammatory cells, with characteristic intranuclear inclusion surrounded by a clear halo. The PCR analysis of peripheral blood and appendix tissue specimen revealed positive VZV DNA. Conclusion: We have shown that varicella-zoster virus infection of the appendix is associated with acute appendicitis and possibly also with severity of the disease.<\/jats:p>","DOI":"10.14712\/18059694.2015.55","type":"journal-article","created":{"date-parts":[[2015,10,20]],"date-time":"2015-10-20T16:25:18Z","timestamp":1445358318000},"page":"150-152","source":"Crossref","is-referenced-by-count":7,"title":["Acute Appendicitis as a Complication of Varicella"],"prefix":"10.14712","volume":"55","author":[{"given":"Zenon","family":"Pogoreli\u0107","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mihovil","family":"Bio\u010di\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivo","family":"Juri\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaudio Pjer","family":"Milunovi\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivana","family":"Mrkli\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5727","published-online":{"date-parts":[[2015,10,20]]},"reference":[{"key":"18059694.2015.55_1","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1001\/jama.298.4.438","volume":"298","author":"Bundy","year":"2007","journal-title":"JAMA"},{"key":"18059694.2015.55_2","doi-asserted-by":"crossref","first-page":"439","DOI":"10.5694\/j.1326-5377.1950.tb80396.x","volume":"1","author":"Camens","year":"1950","journal-title":"Med J Aust"},{"key":"18059694.2015.55_3","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1177\/003693308703200310","volume":"32","author":"Dykes","year":"1987","journal-title":"Scott Med J"},{"key":"18059694.2015.55_4","doi-asserted-by":"crossref","first-page":"138","DOI":"10.2350\/07-06-0299.1","volume":"11","author":"Grynspan","year":"2008","journal-title":"Pediatr Dev Pathol"},{"key":"18059694.2015.55_5","first-page":"538","volume":"69","author":"Harvanek","year":"1990","journal-title":"Rozhl Chir"},{"key":"18059694.2015.55_6","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1080\/00365540410020271","volume":"36","author":"Kanafani","year":"2004","journal-title":"Scand J Infect Dis"},{"key":"18059694.2015.55_7","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.jcv.2009.01.013","volume":"44","author":"Katzoli","year":"2009","journal-title":"J Clin Virol"},{"key":"18059694.2015.55_8","first-page":"23","volume":"46","author":"Ko\u0161\u0107ak","year":"2002","journal-title":"Paediatr Croat"},{"key":"18059694.2015.55_9","doi-asserted-by":"crossref","first-page":"82","DOI":"10.5858\/2002-126-0082-MRA","volume":"126","author":"Paik","year":"2002","journal-title":"Arch Pathol Lab Med"},{"key":"18059694.2015.55_10","first-page":"307","volume":"32","author":"Perko","year":"2008","journal-title":"Coll Anthropol"},{"key":"18059694.2015.55_11","first-page":"567","volume":"105","author":"Wutzler","year":"2008","journal-title":"Dtsch Arztebl Int"}],"container-title":["Acta Medica (Hradec Kralove, Czech Republic)"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/actamedica.lfhk.cuni.cz\/media\/pdf\/am_2012055030150.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/actamedica.lfhk.cuni.cz\/media\/pdf\/am_2012055030150.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T09:40:18Z","timestamp":1779961218000},"score":1,"resource":{"primary":{"URL":"https:\/\/actamedica.lfhk.cuni.cz\/55\/3\/0150\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":11,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2012]]}},"alternative-id":["am_2012055030150"],"URL":"https:\/\/doi.org\/10.14712\/18059694.2015.55","relation":{},"ISSN":["1211-4286","1805-9694"],"issn-type":[{"value":"1211-4286","type":"print"},{"value":"1805-9694","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012]]}}}