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(Hradec Kralove, Czech Repub.)"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>Introduction: Hirschsprung\u2019s disease is a congenital colonic aganglionosis, usually presented as inability or difficulty in passing of meconium, chronic and persistent obstipation, maleficent feeding, vomiting, distension and lethargy. Case presentation: We presented a case of an in-vitro conceived quadruplet premature neonate who presented with pneumoperitoneum caused by transverse colon spontaneous perforation and microcolon appearance of distal bowel, treated by resection and temporary colostomy turns to be a rare manifestation of Hirschsprung\u2019s disease. Conclusion: Assisted reproductive technologies increases chances for multiple pregnancies and may increase chance for major congenital anomalies. Rare manifestation of Hirschsprung\u2019s disease is spontaneous pneumoperitoneum which remains a surgical emergency. Delay in recognizing and treatment can significantly worsen prognosis. In neonate with intestinal perforation one should consider Hirschsprung\u2019s disease.<\/jats:p>","DOI":"10.14712\/18059694.2016.7","type":"journal-article","created":{"date-parts":[[2016,3,10]],"date-time":"2016-03-10T03:52:36Z","timestamp":1457581956000},"page":"144-146","source":"Crossref","is-referenced-by-count":2,"title":["Pneumoperitoneum in in-vitro Conceived Quadruplet Neonate: Rare Manifestation of Hirschsprung\u02bcs Disease \u2013 Report of a Case"],"prefix":"10.14712","volume":"58","author":[{"given":"Jakov","family":"Mihanovi\u0107","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivo","family":"Juri\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zenon","family":"Pogoreli\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivana","family":"Mrkli\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miro","family":"Juki\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dubravko","family":"Furlan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5727","published-online":{"date-parts":[[2016,3,9]]},"reference":[{"key":"18059694.2016.7_1","first-page":"501","volume":"9","author":"Surana","year":"1994","journal-title":"Pediatr Surg Int"},{"key":"18059694.2016.7_2","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.2214\/ajr.148.6.1195","volume":"148","author":"Newman","year":"1987","journal-title":"Am J Roentgenol"},{"key":"18059694.2016.7_3","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1093\/oxfordjournals.humrep.a138250","volume":"8","author":"Balen","year":"1993","journal-title":"Hum Reprod"},{"key":"18059694.2016.7_4","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1093\/humrep\/deg217","volume":"18","author":"Kurinczuk","year":"2003","journal-title":"Hum Reprod"},{"key":"18059694.2016.7_5","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1093\/humrep\/del384","volume":"22","author":"Hansen","year":"2007","journal-title":"Hum Reprod"},{"key":"18059694.2016.7_6","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1093\/humrep\/den387","volume":"24","author":"Reefhuis","year":"2009","journal-title":"Hum Reprod"},{"key":"18059694.2016.7_7","first-page":"490","volume":"3","author":"Andersen","year":"2004","journal-title":"Hum Reprod"},{"key":"18059694.2016.7_8","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1093\/humrep\/17.5.1391","volume":"17","author":"Koivurova","year":"2002","journal-title":"Hum Reprod"},{"key":"18059694.2016.7_9","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1056\/NEJMoa010035","volume":"346","author":"Hansen","year":"2002","journal-title":"N Eng J Med"},{"key":"18059694.2016.7_10","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1007\/BF00166865","volume":"1","author":"Polley","year":"1986","journal-title":"Pediatr Surg Int"},{"key":"18059694.2016.7_11","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/0022-3468(73)90395-3","volume":"8","author":"Swenson","year":"1973","journal-title":"J Pediatr Surg"},{"key":"18059694.2016.7_12","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1007\/s00383-009-2488-6","volume":"25","author":"Khan","year":"2009","journal-title":"Pediatr Surg Int"}],"container-title":["Acta Medica (Hradec Kralove, Czech Republic)"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/actamedica.lfhk.cuni.cz\/media\/pdf\/am_2015058040144.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/actamedica.lfhk.cuni.cz\/media\/pdf\/am_2015058040144.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T09:33:23Z","timestamp":1779960803000},"score":1,"resource":{"primary":{"URL":"https:\/\/actamedica.lfhk.cuni.cz\/58\/4\/0144\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":12,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2015]]}},"alternative-id":["am_2015058040144"],"URL":"https:\/\/doi.org\/10.14712\/18059694.2016.7","relation":{},"ISSN":["1211-4286","1805-9694"],"issn-type":[{"value":"1211-4286","type":"print"},{"value":"1805-9694","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]}}}