{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T10:08:25Z","timestamp":1779962905382,"version":"3.53.1"},"reference-count":46,"publisher":"Charles University in Prague, Karolinum Press","issue":"3","license":[{"start":{"date-parts":[[2021,11,11]],"date-time":"2021-11-11T00:00:00Z","timestamp":1636588800000},"content-version":"vor","delay-in-days":314,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,11,11]],"date-time":"2021-11-11T00:00:00Z","timestamp":1636588800000},"content-version":"tdm","delay-in-days":314,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["actamedica.lfhk.cuni.cz"],"crossmark-restriction":true},"short-container-title":["Acta Med. (Hradec Kralove, Czech Repub.)"],"published-print":{"date-parts":[[2021]]},"abstract":"<jats:p>Spindle cell lipoma (SCL) is an uncommon histological variant of lipoma that accounts for 1.5% of all adipose tumors. It rarely occurs in the oral cavity. The most common sites of involvement are the buccal mucosa, tongue, lip, alveolar mucosa, gingiva, and palate. Submandibular space is a very rare site of occurrence for SCL. When occurs in this site, SCL mainly involves the 4th\u20137th decade with a female predominance. Due to wide communications of submandibular space, the actual extent and appearance of the lesions present here gets masked up especially those involving the deeper tissues leading to an inaccurate diagnosis. Wide overlap of clinical and histopathological features of SCL to other clinical pathologies leads to a challenging task for the clinicians to reach an accurate diagnosis. To our knowledge, only four cases of intraoral SCL involving the submandibular region directly or indirectly have been reported in the literature. Here we represent another rare case of SCL in an 18-year-old male patient along with a concise review of the literature. This case appears to be quite rare due to its location (submandibular space), age, and sex of the patient (18\/M).<\/jats:p>","DOI":"10.14712\/18059694.2021.30","type":"journal-article","created":{"date-parts":[[2021,11,15]],"date-time":"2021-11-15T05:07:26Z","timestamp":1636952846000},"page":"174-182","update-policy":"https:\/\/doi.org\/10.14712\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Spindle Cell Lipoma Occurring in the Submandibular Space: Fifth Case Reported along with a Concise Review of the Literature"],"prefix":"10.14712","volume":"64","author":[{"given":"Manveen Kaur","family":"Jawanda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harshaminder Kaur","family":"Grewal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonia","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vineet","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ravi","family":"Narula","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5727","published-online":{"date-parts":[[2021,11,11]]},"reference":[{"key":"18059694.2021.30_1","doi-asserted-by":"crossref","first-page":"1852","DOI":"10.1002\/1097-0142(197511)36:5<1852::AID-CNCR2820360542>3.0.CO;2-U","volume":"36","author":"Enzinger","year":"1975","journal-title":"Cancer"},{"key":"18059694.2021.30_2","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1111\/j.1365-2559.1987.tb01884.x","volume":"11","author":"Fletcher","year":"1987","journal-title":"Histopathology"},{"key":"18059694.2021.30_3","doi-asserted-by":"crossref","first-page":"379","DOI":"10.4103\/0377-4929.55000","volume":"52","author":"Pusiol","year":"2009","journal-title":"Indian J Pathol Microbiol"},{"key":"18059694.2021.30_4","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1017\/S0022215105004597","volume":"120","author":"El-Monem","year":"2006","journal-title":"J Laryngol Otol"},{"key":"18059694.2021.30_5","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.omsc.2015.04.002","author":"Miloro","year":"2015","journal-title":"Oral Maxillofac Surg Cases"},{"key":"18059694.2021.30_6","unstructured":"Shafer WG, Hine MK, Levy BM. Shafer\u2019s textbook of oral pathology.6th ed. Elsevier publications: Noida, India 2009, p. 138."},{"key":"18059694.2021.30_7","first-page":"805730","author":"Milhan","year":"2015","journal-title":"Case Reports Pathol"},{"key":"18059694.2021.30_8","unstructured":"Kempson RL, Fletcher CDM, Evans HL, Hendrickson MR, Sibley RK. Tumors of the soft tissues Atlas of tumor pathology. Bethesda: Third Series Armed Forces Institute of Pathology, 2001, p. 203\u20138."},{"key":"18059694.2021.30_9","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.anl.2005.01.013","volume":"32","author":"Piatteli","year":"2005","journal-title":"Auris Nasus Larynx"},{"key":"18059694.2021.30_10","doi-asserted-by":"crossref","first-page":"7","DOI":"10.7243\/2055-091X-2-7","volume":"2","author":"Amore","year":"2015","journal-title":"J Histol Histopathol"},{"key":"18059694.2021.30_11","doi-asserted-by":"crossref","first-page":"820","DOI":"10.5858\/2001-125-0820-SCLOTP","volume":"125","author":"Fasig","year":"2001","journal-title":"Arch Pathol Lab Med"},{"key":"18059694.2021.30_12","doi-asserted-by":"crossref","first-page":"875","DOI":"10.5858\/2006-130-875-LFM","volume":"130","author":"Rosenthal","year":"2006","journal-title":"Arch Pathol Lab Med"},{"key":"18059694.2021.30_13","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/0030-4220(84)90260-3","volume":"57","author":"McDaniel","year":"1984","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"18059694.2021.30_14","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1177\/019459988910100519","volume":"101","author":"Levy","year":"1989","journal-title":"Otolaryngol Head Neck Surg"},{"key":"18059694.2021.30_15","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1177\/014556130108000414","volume":"80","author":"Baumann","year":"2001","journal-title":"Ear, Nose, & Throat Journal"},{"key":"18059694.2021.30_16","first-page":"401","volume":"11","author":"Coimbra","year":"2006","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"18059694.2021.30_17","first-page":"291","volume":"2","author":"Yalc\u0327in","year":"2015","journal-title":"J Dent App"},{"key":"18059694.2021.30_18","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1097\/01.dad.0000189615.13641.4b","volume":"28","author":"Billings","year":"2006","journal-title":"Am J Dermatopathol"},{"key":"18059694.2021.30_19","first-page":"2138928","author":"Malthiery","year":"2019","journal-title":"Case Reports in Dentistry"},{"key":"18059694.2021.30_20","doi-asserted-by":"crossref","first-page":"72S","DOI":"10.47102\/annals-acadmedsg.V33N4p72S","volume":"33","author":"Tan","year":"2004","journal-title":"Ann Acad Med Singapore"},{"key":"18059694.2021.30_21","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.1007\/s00268-017-3901-2","volume":"41","author":"Kokong","year":"2017","journal-title":"World J Surg"},{"key":"18059694.2021.30_22","first-page":"114","volume":"2","author":"Joshi","year":"2018","journal-title":"Acta Scient Dent Sci"},{"key":"18059694.2021.30_23","first-page":"347","volume":"3","author":"Sabhalok","year":"2016","journal-title":"PlastAesthet Res"},{"key":"18059694.2021.30_24","doi-asserted-by":"crossref","first-page":"48","DOI":"10.4103\/jcis.JCIS_46_18","volume":"8","author":"Kessler","year":"2018","journal-title":"J Clin Imaging Sci"},{"key":"18059694.2021.30_25","first-page":"e597","volume":"8","author":"Egido-Moreno","year":"2016","journal-title":"J Clin Exp Dent"},{"key":"18059694.2021.30_26","doi-asserted-by":"crossref","first-page":"493","DOI":"10.3348\/kjr.2013.14.3.493","volume":"14","author":"Lee","year":"2013","journal-title":"Korean J Radiol"},{"key":"18059694.2021.30_27","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1590\/S1808-86942011000300021","volume":"77","author":"Upadhyay","year":"2011","journal-title":"Braz J Otorhinolaryngol"},{"key":"18059694.2021.30_28","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1067\/moe.2002.120520","volume":"93","author":"Darling","year":"2002","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"18059694.2021.30_29","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1053\/adpa.2001.26973","volume":"5","author":"Said-Al-Naief","year":"2001","journal-title":"Ann Diagn Pathol"},{"key":"18059694.2021.30_30","first-page":"2613","volume":"12","author":"Chen","year":"2019","journal-title":"Int J Clin Exp Pathol"},{"key":"18059694.2021.30_31","unstructured":"Miettinen MM, Mandahl N. Spindle cell lipoma\/pleomorphic lipoma. In: Fletcher CDM, Unni KK, Mertens F, editors. Pathology and genetics of tumours of soft tissue and bone. Lyon: World Health Classification of Tumours International Agency for Research of Cancer (IARC) IARC Press; 2002: 31\u20132."},{"key":"18059694.2021.30_32","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1046\/j.1440-1827.2001.01193.x","volume":"51","author":"Horiuchi","year":"2001","journal-title":"Pathology Int"},{"key":"18059694.2021.30_33","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1097\/00000478-198107000-00003","volume":"5","author":"Bole","year":"1981","journal-title":"Am J Surg Pathol"},{"key":"18059694.2021.30_34","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1002\/path.1711580308","volume":"157","author":"Behan","year":"1989","journal-title":"J Pathol"},{"key":"18059694.2021.30_35","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1111\/j.1600-0714.1994.tb01120.x","volume":"23","author":"Lombardi","year":"1994","journal-title":"J Oral Pathol Med"},{"key":"18059694.2021.30_36","first-page":"546","volume":"23","author":"Templeton","year":"1996","journal-title":"J CutanPathol"},{"key":"18059694.2021.30_37","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1097\/DAD.0b013e3181d0c587","volume":"32","author":"Wood","year":"2010","journal-title":"Am J Dermatopathol"},{"key":"18059694.2021.30_38","doi-asserted-by":"crossref","first-page":"561","DOI":"10.4103\/IJPM.IJPM_473_17","volume":"61","author":"Bajpai","year":"2018","journal-title":"Indian J Pathol Microbiol"},{"key":"18059694.2021.30_39","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/0278-2391(90)90438-8","volume":"48","author":"Dominguez","year":"1990","journal-title":"J Oral Maxillofac Surg"},{"key":"18059694.2021.30_40","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1053\/adpa.2002.32375","volume":"6","author":"Nascimento","year":"2002","journal-title":"Ann Diagn Pathol"},{"key":"18059694.2021.30_41","unstructured":"Weiss SW, Goldblum JR. Enzinger and Weiss\u2019s soft Tissue Tumors. St. Louis: Mosby; 2001."},{"key":"18059694.2021.30_42","doi-asserted-by":"crossref","first-page":"844","DOI":"10.12659\/AJCR.895474","volume":"16","author":"Jaeger","year":"2015","journal-title":"Am J Case Rep"},{"key":"18059694.2021.30_43","doi-asserted-by":"crossref","first-page":"196","DOI":"10.4236\/ss.2013.43037","volume":"4","author":"Manor","year":"2013","journal-title":"Surgical Science"},{"key":"18059694.2021.30_44","doi-asserted-by":"crossref","first-page":"e373","DOI":"10.4317\/medoral.22931","volume":"24","author":"Linares","year":"2019","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"18059694.2021.30_45","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.anndiagpath.2011.01.003","volume":"15","author":"Manor","year":"2011","journal-title":"Ann Diagn Pathol"},{"key":"18059694.2021.30_46","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1007\/s00405-009-1010-z","volume":"267","author":"Julliasse","year":"2010","journal-title":"Eur Arch Otorhinolaryngol"}],"container-title":["Acta Medica (Hradec Kralove, Czech Republic)"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/actamedica.lfhk.cuni.cz\/media\/pdf\/am_2021064030174.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/actamedica.lfhk.cuni.cz\/media\/pdf\/am_2021064030174.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T09:36:28Z","timestamp":1779960988000},"score":1,"resource":{"primary":{"URL":"https:\/\/actamedica.lfhk.cuni.cz\/64\/3\/0174\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":46,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2021]]}},"alternative-id":["am_2021064030174"],"URL":"https:\/\/doi.org\/10.14712\/18059694.2021.30","relation":{},"ISSN":["1211-4286","1805-9694"],"issn-type":[{"value":"1211-4286","type":"print"},{"value":"1805-9694","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021]]}}}