{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T10:06:03Z","timestamp":1779962763318,"version":"3.53.1"},"reference-count":19,"publisher":"Charles University in Prague, Karolinum Press","issue":"1","license":[{"start":{"date-parts":[[2022,7,6]],"date-time":"2022-07-06T00:00:00Z","timestamp":1657065600000},"content-version":"vor","delay-in-days":186,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2022,7,6]],"date-time":"2022-07-06T00:00:00Z","timestamp":1657065600000},"content-version":"tdm","delay-in-days":186,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["actamedica.lfhk.cuni.cz"],"crossmark-restriction":true},"short-container-title":["Acta Med. (Hradec Kralove, Czech Repub.)"],"published-print":{"date-parts":[[2022]]},"abstract":"<jats:p>Background: Acute nonspecific mesenteric lymphadenitis (ANML) is a common cause of acute abdominal pain in children with no specific treatment. Methods: A total of 13 patients (6 boys, 7 girls) aged 7.3 (5\u201313.5) years with severe acute abdominal pain were evaluated using ultrasonography and laboratory tests to establish the diagnosis of ANML. They were treated with prednisone 1 mg\/kg (max 40 mg daily) for a maximum of 5 days. The intensity of abdominal pain was evaluated before and after treatment using a numeric rating scale. Results: All patients had pain scores above 6\/10 before, and below 4\/10 after treatment with prednisone. Intensity of abdominal pain after treatment for 1\u20135 days decreased significantly (p &lt; 0.001), with no recurrence at follow-up within 3 months. All other pre-existing signs and symptoms, such as nausea, vomiting, anorexia, fever, diarrhea, and constipation were found to disappear with no adverse effects of corticosteroid therapy. Conclusion: These results suggest that the treatment with prednisone in selective patients with ANML can reduce the duration of abdominal pain.<\/jats:p>","DOI":"10.14712\/18059694.2022.12","type":"journal-article","created":{"date-parts":[[2022,7,6]],"date-time":"2022-07-06T15:56:10Z","timestamp":1657122970000},"page":"25-28","update-policy":"https:\/\/doi.org\/10.14712\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Efficacy of Prednisone in Children with Acute Nonspecific Mesenteric Lymphadenitis: A Pilot Study"],"prefix":"10.14712","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7818-3140","authenticated-orcid":false,"given":"Momcilo","family":"Pavlovic","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeljko","family":"Rokvic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karolina","family":"Berenji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5727","published-online":{"date-parts":[[2022,7,6]]},"reference":[{"key":"18059694.2022.12_1","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1007\/s00247-005-1462-2","volume":"35","author":"Karmazyn","year":"2005","journal-title":"Pediatr Radiol"},{"key":"18059694.2022.12_2","doi-asserted-by":"crossref","unstructured":"Maconi G. Mesenteric lymphadenopathy. In: Maconi G, Bianchi Porro G, eds. Ultrasound of the gastrointestinal tract. 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